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See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules

선웅|김현정|이은수
대한배뇨장애요실금학회 (Korean Continence Society)|2016.11|International Neurourology Journal|제20권 제1호|pp. 15-22

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참고문헌

키워드

ImagingThree-DimensionalNeuroscienceOptical Tissue ClearingImmunolabelingMolecular Diagnosis

초록

Tissue clearing technology is currently one of the fastest growing fields in biomedical sciences. Tissue clearing techniques have become a powerful approach to understand further the structural information of intact biological tissues. Moreover, technological improvements in tissue clearing and optics allowed the visualization of neural network in the whole brain tissue with subcellular resolution. Here, we described an overview of various tissue-clearing techniques, with focus on the tissue-hydrogel mediated clearing methods, and discussed the main advantages and limitations of transparent tissue for clinical diagnosis.

Abstract

Tissue clearing technology is currently one of the fastest growing fields in biomedical sciences. Tissue clearing techniques have become a powerful approach to understand further the structural information of intact biological tissues. Moreover, technological improvements in tissue clearing and optics allowed the visualization of neural network in the whole brain tissue with subcellular resolution. Here, we described an overview of various tissue-clearing techniques, with focus on the tissue-hydrogel mediated clearing methods, and discussed the main advantages and limitations of transparent tissue for clinical diagnosis.

참고문헌 (30)

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