Do Failure of Posterior Tibial Nerve Stimulation Precludes to Use Sacral Neuromodulation in Patient With Overactive Bladder?
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Purpose: To evaluate the outcomes of sacral neuromodulation (SNM) after failure of transcutaneous posterior tibial nerve stimulation (TPTNS) in patients with overactive bladder (OAB). Methods: A retrospective study was conducted in 3 university hospitals and included all patients with OAB and treated with SNM after TPTNS had been tried between October 2008 and May 2018. The primary endpoint was the proportion of definitive SNM device implantation in patients with 50% objective and/or subjective improvement after a test period (stage 1). The secondary outcomes of interest were changes of the number of diurnal voids and nocturia episodes per 24 hours between the end of TPTNS and the end of stage 1. Results: Overall, 28 of the 43 patients included achieved at least 50% objective and/or subjective improvement during stage 1 and underwent an Interstim II implantation (65.1%). The mean daytime frequency decreased significantly from 10.3/day at the end of TPTNS to 7.8 diurnal voids/day at the end of SNM stage 1 (P=0.01). The mean number of nocturia episodes decreased from 2.5/night at the end of TPTNS to 2.1/night at the end of stage 1, but this did not reach statistical significance (P=0.18). There was no other parameter significantly associated with response to SNM Conclusions: SNM might improve OAB symptoms in most patients who experienced no or poor efficacy with TPTNS. History of failed TPTNS should not preclude the use of SNM in OAB patients.
Abstract
Purpose: To evaluate the outcomes of sacral neuromodulation (SNM) after failure of transcutaneous posterior tibial nerve stimulation (TPTNS) in patients with overactive bladder (OAB). Methods: A retrospective study was conducted in 3 university hospitals and included all patients with OAB and treated with SNM after TPTNS had been tried between October 2008 and May 2018. The primary endpoint was the proportion of definitive SNM device implantation in patients with 50% objective and/or subjective improvement after a test period (stage 1). The secondary outcomes of interest were changes of the number of diurnal voids and nocturia episodes per 24 hours between the end of TPTNS and the end of stage 1. Results: Overall, 28 of the 43 patients included achieved at least 50% objective and/or subjective improvement during stage 1 and underwent an Interstim II implantation (65.1%). The mean daytime frequency decreased significantly from 10.3/day at the end of TPTNS to 7.8 diurnal voids/day at the end of SNM stage 1 (P=0.01). The mean number of nocturia episodes decreased from 2.5/night at the end of TPTNS to 2.1/night at the end of stage 1, but this did not reach statistical significance (P=0.18). There was no other parameter significantly associated with response to SNM Conclusions: SNM might improve OAB symptoms in most patients who experienced no or poor efficacy with TPTNS. History of failed TPTNS should not preclude the use of SNM in OAB patients.
참고문헌 (23)
- Cornu JN, "Prevalence and initial management of overactive bladder in France : a cross-sectional study", Prog Urol, 26, pp.415~424 (2016)
- Irwin DE, "Worldwide prevalence estimates of lower urinary tract symptoms, overactive bladder, urinary incontinence and bladder outlet obstruction", BJU Int, 108, pp.1132~1138 (2011)
- Irwin DE, "The economic impact of overactive bladder syndrome in six Western countries", BJU Int, 103, pp.202~209 (2009)
- Gormley EA, "Diagnosis and treatment of overactive bladder(nonneurogenic)in adults : AUA", SUFU guideline amendment, 2015, pp.193, 1572~1580
- Corcos J, "CUA guideline on adult overactive bladder", Can Urol Assoc J, 11, pp.E142~73 (2017)
- Nambiar AK, "EAU guidelines on assessment and nonsurgical management of urinary incontinence", Eur Urol, 73, pp.596~609 (2018)
- Booth J, "The effectiveness of transcutaneous tibial nerve stimulation(TTNS)for adults with overactive bladder syndrome : a systematic review", Neurourol Urodyn, 37, pp.528~541 (2018)
- Ramírez-García I, "Efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome : randomized control trial", Neurourol Urodyn, 38, pp.261~268 (2019)
- Ammi M, "Transcutaneous posterior tibial nerve stimulation : evaluation of a therapeutic option in the management of anticholinergic refractory overactive bladder", Int Urogynecol J, 25, pp.1065~1069 (2014)
- de Sèze M, "Transcutaneous posterior tibial nerve stimulation for treatment of the overactive bladder syndrome in multiple sclerosis : results of a multicenter prospective study", Neurourol Urodyn, 30, pp.306~311 (2011)
- Leroux PA, "Transcutaneous tibial nerve stimulation : 2 years follow-up outcomes in the management of anticholinergic refractory overactive bladder", World J Urol, 36, pp.1455~1460 (2018)
- Amundsen CL, "Two-year outcomes of sacral neuromodulation versus onabotulinumtoxinA for refractory urgency urinary incontinence : a randomized trial", Eur Urol, 74, pp.66~73 (2018)
- Choudhary M, "Effect of tibial nerve stimulation on bladder afferent nerve activity in a rat detrusor overactivity model", Int J Urol, 23, pp.253~258 (2016)
- Goldman HB, "International Continence Society best practice statement for use of sacral neuromodulation", Neurourol Urodyn, 37, pp.1823~1848 (2018)
- Liberman D, "Sacral neuromodulation in urological practice", Urology, 99, pp.14~22 (2017)
- Apostolidis A, "Can we create a valid treatment algorithm for patients with drug resistant overactive bladder(OAB)syndrome or detrusor overactivity(DO)? Results from a think tank(ICI-RS 2015)", Neurourol Urodyn, 36, pp.882~893 (2017)
- Schreiner L, "Randomized trial of transcutaneous tibial nerve stimulation to treat urge urinary incontinence in older women", Int Urogynecol J, 21, pp.1065~1070 (2010)
- Siegel S, "Results of a prospective, randomized, multicenter study evaluating sacral neuromodulation with InterStim therapy compared to standard medical therapy at 6-months in subjects with mild symptoms of overactive bladder", Neurourol Urodyn, 34, pp.224~230 (2015)
- Gajewski JB, "Does our limited knowledge of the mechanisms of neural stimulation limit its benefits for patients with overactive bladder? ICI-RS 2013", Neurourol Urodyn, 33, pp.618~621 (2014)
- Leng WW, "How sacral nerve stimulation neuromodulation works", Urol Clin North Am, 32, pp.11~18 (2005)
- Weissbart SJ, "Specific changes in brain activity during urgency in women with overactive bladder after successful sacral neuromodulation : a functional magnetic resonance imaging study", J Urol, 200, pp.382~388 (2018)
- Finazzi-Agrò E, "Percutaneous tibial nerve stimulation produces effects on brain activity : study on the modifications of the long latency somatosensory evoked potentials", Neurourol Urodyn, 28, pp.320~324 (2009)
- Haab F, "Comprehensive evaluation of bladder and urethral dysfunction symptoms : development and psychometric validation of the Urinary Symptom Profile(USP)questionnaire", Urology, 71, pp.646~656 (2008)