Role of Transcutaneous Electrical Nerve Stimulation in Treating Children With Overactive Bladder From Pooled Analysis of 8 Randomized Controlled Trials
1
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Purpose: Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-analysis guideline was followed in this study. The MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases, as well as the reference lists of the retrieved studies, were used to find trials relevant for assessing the use of TENS to treat OAB. Results: Of the 246 records identified, 8 publications were analyzed in our study. Our analysis found that TENS resulted in a greater decrease of wet days/wk, daily voiding frequency, daily incontinence episodes, and daily number of voids than was observed in the control group. Furthermore, TENS-treated patients showed similar visual analogue scale (VAS) scores to patients in the control group, demonstrating that the application of TENS did not increase patients’ discomfort and pain. TENS had a relative advantage in the number of partial responses, but no clear differences were found in frequency of no response or a full response compared to the control group. In urodynamic testing, TENS led to obvious improvements in average voided volume and maximum voided volume in children with OAB. Conclusions: TENS had a remarkable effect on the improvement of urodynamic indexes and objective OAB symptoms without a significant increase in VAS scores for children with OAB.
Abstract
Purpose: Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-analysis guideline was followed in this study. The MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases, as well as the reference lists of the retrieved studies, were used to find trials relevant for assessing the use of TENS to treat OAB. Results: Of the 246 records identified, 8 publications were analyzed in our study. Our analysis found that TENS resulted in a greater decrease of wet days/wk, daily voiding frequency, daily incontinence episodes, and daily number of voids than was observed in the control group. Furthermore, TENS-treated patients showed similar visual analogue scale (VAS) scores to patients in the control group, demonstrating that the application of TENS did not increase patients’ discomfort and pain. TENS had a relative advantage in the number of partial responses, but no clear differences were found in frequency of no response or a full response compared to the control group. In urodynamic testing, TENS led to obvious improvements in average voided volume and maximum voided volume in children with OAB. Conclusions: TENS had a remarkable effect on the improvement of urodynamic indexes and objective OAB symptoms without a significant increase in VAS scores for children with OAB.
참고문헌 (33)
- Nevéus T, "The standardization of terminology of lower urinary tract function in children and adolescents : report from the Standardisation Committee of the International Children’s Continence Society", J Urol, 176, pp.314~324 (2006)
- Rawashdeh YF, "International Children’s Continence Society’s recommendations for therapeutic intervention in congenital neuropathic bladder and bowel dysfunction in children", Neurourol Urodyn, 31, pp.615~620 (2012)
- Austin PF, "The standardization of terminology of lower urinary tract function in children and adolescents : update report from the standardization committee of the International Children’s Continence Society", Neurourol Urodyn, 35, pp.471~481 (2016)
- Kajiwara M, "Nocturnal enuresis and overactive bladder in children : an epidemiological study", Int J Urol, 13, pp.36~41 (2006)
- Chung JM, "Prevalence and associated factors of overactive bladder in Korean children 5-13 years old : a nationwide multicenter study", Urology, 73, pp.63~67 (2009)
- Mulders MM, "Urotherapy in children : quantitative measurements of daytime urinary incontinence before and after treatment according to the new definitions of the International Children’s Continence Society", J Pediatr Urol, 7, pp.213~218 (2011)
- Hagstroem S, "Timer watch assisted urotherapy in children : a randomized controlled trial", J Urol, 184, pp.1482~1488 (2010)
- Barroso U Jr, "Electrical stimulation for lower urinary tract dysfunction in children : a systematic review of the literature", Neurourol Urodyn, 30, pp.1429~1436 (2011)
- De Gennaro M, "Current state of nerve stimulation technique for lower urinary tract dysfunction in children", J Urol, 185, pp.1571~1577 (2011)
- Moher D, "Preferred reporting items for systematic reviews and meta-analyses:the PRISMA statement", J Clin Epidemiol, 62, pp.1006~1012 (2009)
- Alejandro J, "Randomised controlled trials" (1998), BMJ Publishing Group
- DerSimonian R, "Meta-analysis in clinical trials", Control Clin Trials, 7, pp.177~188 (1986)
- Borch L, "Transcutaneous electrical nerve stimulation combined with oxybutynin is superior to monotherapy in children with urge incontinence: a randomized, placebo controlled study", J Urol, 198, pp.430~435 (2017)
- Borch L, "No immediate effect on urodynamic parameters during transcutaneous electrical nerve stimulation (TENS) in children with overactive bladder and daytime incontinence-A randomized, doubleblind, placebo-controlled study", Neurourol Urodyn, 36, pp.1788~1795 (2017)
- De Paula LIDS, "Parasacral transcutaneous electrical neural stimulation (PTENS) once a week for the treatment of overactive bladder in children: a randomized controlled trial", J Pediatr Urol, 13, pp.263.e1~263.e6 (2017)
- Boudaoud N, "Management of refractory overactive bladder in children by transcutaneous posterior tibial nerve stimulation : A controlled study", J Pediatr Urol, 11, pp.138.e1~138.e10 (2015)
- Patidar N, "Transcutaneous posterior tibial nerve stimulation in pediatric overactive bladder : a preliminary report", J Pediatr Urol, 11, pp.351.e1~351.e6 (2015)
- Sillén U, "Effects of transcutaneous neuromodulation(TENS)on overactive bladder symptoms in children : a randomized controlled trial", J Pediatr Urol, 10, pp.1100~1105 (2014)
- Lordêlo P, "Transcutaneous electrical nerve stimulation in children with overactive bladder : a randomized clinical trial", J Urol, 184, pp.683~689 (2010)
- Hagstroem S, "Transcutaneous electrical nerve stimulation for refractory daytime urinary urge incontinence", J Urol, 182(4 Suppl), pp.2072~2078 (2009)
- Quintiliano F, "Transcutaneous parasacral electrical stimulation vs oxybutynin for the treatment of overactive bladder in children : a randomized clinical trial", J Urol, 193(5 Suppl), pp.1749~1753 (2015)
- Humphreys MR, "Preliminary results of sacral neuromodulation in 23children", J Urol, 176, pp.2227~2231 (2006)
- Bower WF, "A pilot study of the home application of transcutaneous neuromodulation in children with urgency or urge incontinence", J Urol, 166, pp.2420~2422 (2001)
- Clarke MC, "Improvement of quality of life in children with slow transit constipation after treatment with transcutaneous electrical stimulation", J Pediatr Surg, 44, pp.1268~1272 (2009)
- De Bock F, "Can the use of different parameters and waveforms improve the results of intravesical electrical stimulation : a pilot study in the rat", Neurourol Urodyn, 28, pp.246~250 (2009)
- De Bock F, "Influence of nerve transsections and combined bladder filling on intravesical electrostimulation-induced bladder contraction in the rat", Eur Urol, 56, pp.527~532 (2009)
- Fall M, "Electrical stimulation. A physiologic approach to the treatment of urinary incontinence", Urol Clin North Am, 18, pp.393~407 (1991)
- Evans SN, "Neurological disorders in the ageing population and their urological implications", Br J Urol, 82(Suppl 1), pp.71~78 (1998)
- Sundin T, "Detrusor inhibition induced from mechanical stimulation of the anal region and from electrical stimulation of pudendal nerve afferents. An experimental study in cats", Invest Urol, 11, pp.374~378 (1974)
- Bower WF, "A review of non-invasive electro neuromodulation as an intervention for non-neurogenic bladder dysfunction in children", Neurourol Urodyn, 23, pp.63~67 (2004)
- Fitzgerald MP, "Childhood urinary symptoms predict adult overactive bladder symptoms", J Urol, 175(3 Pt 1), pp.989~993 (2006)
- Kuh D, "Urinary incontinence in middle aged women : childhood enuresis and other lifetime risk factors in a British prospective cohort", J Epidemiol Community Health, 53, pp.453~458 (1999)