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Noninvasive Urodynamic Evaluation

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The longevity of the world’s population is increasing, and among male patients, complaints of lower urinary tract symptoms (LUTS) are growing. Testing to diagnose LUTS and to differentiate between the various causes should be quick, easy, cheap, specific, not too bothersome for the patient, and noninvasive or minimally so. Urodynamic evaluation is the gold standard for diagnosing bladder outlet obstruction (BOO) but presents some inconveniences such as embarrassment, pain, and dysuria; furthermore,19% of cases experience urinary retention, macroscopic hematuria, or urinary tract infection. A greater number of resources in the diagnostic armamentarium could increase the opportunity for selecting less invasive tests. A number of groups have risen to this challenge and have formulated and developed ideas and technologies to improve noninvasive methods to diagnosis BOO. These techniques start with flowmetry, an increase in the interest of ultrasound, and finally the performance of urodynamic evaluation without a urethral catheter. Flowmetry is not sufficient for confirming a diagnosis of BOO. Ultrasound of the prostate and the bladder can help to assess BOO noninvasively in all men and can be useful for evaluating the value of BOO at assessment and during treatment of benign prostatic hyperplasia patients in the future. The great advantages of noninvasive urodynamics are as follows: minimal discomfort, minimal risk of urinary tract infection, and low cost. This method can be repeated many times, permitting the evaluation of obstruction during clinical treatment. A urethral connector should be used to diagnose BOO, in evaluation for surgery, and in screening for treatment. In the future, noninvasive urodynamics can be used to identify patients with BOO to initiate early medical treatment and evaluate the results. This approach permits the possibility of performing surgery before detrusor damage occurs.

Abstract

The longevity of the world’s population is increasing, and among male patients, complaints of lower urinary tract symptoms (LUTS) are growing. Testing to diagnose LUTS and to differentiate between the various causes should be quick, easy, cheap, specific, not too bothersome for the patient, and noninvasive or minimally so. Urodynamic evaluation is the gold standard for diagnosing bladder outlet obstruction (BOO) but presents some inconveniences such as embarrassment, pain, and dysuria; furthermore,19% of cases experience urinary retention, macroscopic hematuria, or urinary tract infection. A greater number of resources in the diagnostic armamentarium could increase the opportunity for selecting less invasive tests. A number of groups have risen to this challenge and have formulated and developed ideas and technologies to improve noninvasive methods to diagnosis BOO. These techniques start with flowmetry, an increase in the interest of ultrasound, and finally the performance of urodynamic evaluation without a urethral catheter. Flowmetry is not sufficient for confirming a diagnosis of BOO. Ultrasound of the prostate and the bladder can help to assess BOO noninvasively in all men and can be useful for evaluating the value of BOO at assessment and during treatment of benign prostatic hyperplasia patients in the future. The great advantages of noninvasive urodynamics are as follows: minimal discomfort, minimal risk of urinary tract infection, and low cost. This method can be repeated many times, permitting the evaluation of obstruction during clinical treatment. A urethral connector should be used to diagnose BOO, in evaluation for surgery, and in screening for treatment. In the future, noninvasive urodynamics can be used to identify patients with BOO to initiate early medical treatment and evaluate the results. This approach permits the possibility of performing surgery before detrusor damage occurs.

참고문헌 (12)

  1. "Guidelines on management of male lower urinary tract symptoms (LUTS), incl. Benign prostatic obstruction (BPO)" (2012)[URL]
  2. Gomes CM, "Voiding dysfunction and urodynamic abnormalities in elderly patients", Rev Hosp Clin Fac Med Sao Paulo, 59, pp.206~215 (2004)
  3. Klingler HC, "Morbidity of the evaluation of the lower urinary tract with transurethral multichannel pressure-flow studies", J Urol, 159, pp.191~194 (1998)
  4. Kojima M, "Ultrasonic estimation of bladder weight as a measure of bladder hypertrophy in men with infravesical obstruction: a preliminary report", Urology, 47, pp.942~947 (1996)
  5. Oelke M, "Diagnostic accuracy of noninvasive tests to evaluate bladder outlet obstruction in men: detrusor wall thickness, uroflowmetry, postvoid residual urine, and prostate volume", Eur Urol, 52, pp.827~834 (2007)
  6. Reis LO, "Intravesical protrusion of the prostate as a predictive method of bladder outlet obstruction", Int Braz J Urol, 34, pp.627~633 (2008)
  7. Huang T, "Predictive value of resistive index, detrusor wall thickness and ultrasound estimated bladder weight regarding the outcome after transurethral prostatectomy for patients with lower urinary tract symptoms suggestive of benign prostatic obstruction", Int J Urol, 19, pp.343~350 (2012)
  8. Schafer W, "Non-invasive pressure", flow measurement for precise grading of bladder outflow obstruction, 1994, pp.151(Suppl), 323A~
  9. McRae LP, "Noninvasive quantitative method for measuring isovolumetric bladder pressure and urethral resistance in the male: I. Experimental validation of the theory", Neurourol Urodyn, 14, pp.101~114 (1995)
  10. Gommer ED, "Validity of a non-invasive determination of the isovolumetric bladder pressure during voiding in men with LUTS", Neurourol Urodyn, 18, pp.477~486 (1999)
  11. D’Ancona CA, "New method for minimally invasive urodynamic assessment in men with lower urinary tract symptoms", Urology, 71, pp.75~78 (2008)
  12. McIntosh SL, "Noninvasive measurement of bladder pressure. Does mechanical interruption of the urinary stream inhibit detrusor contraction?", J Urol, 169, pp.1003~1006 (2003)

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