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Analysis of Trend of Studies on Microneedle Treatment System (MTS)

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Objectives: The purpose of this study was to analyze the microneedle therapy system (MTS) and its research methods for the past 10 years in Korea. Methods: Data on microneedle therapy system were collected using NDSL, KISS, RISS, and OASIS electronic databases from January 2010 to August 2021. “microneedle,” “derma stamp,” “microneedle therapy system” were used as the keywords. The present study, however, excluded data that were 1) unrelated to the microneedle therapy system, 2) from review/meta/protocol studies, and 3) from overseas studies. Data selected through the primary screening process, animal studies, case reports, and clinical data were included in the analysis. However, information data not related to the microneedle therapy system were excluded from the study. Results: Among the MTS-related papers published from January 2010 to August 2021, 7 animal research, 2 clinical trials, and 10 case studies were published. Based on the research topics, there were 8 papers on skin improvement and skin diseases, 7 papers on hair growth and hair loss, 3 papers on stability, and 1 paper on peripheral facial paralysis. Conclusion: Most of the studies related to MTS focused on skin, hair, and stability. The effect of MTS on hair growth and skin improvement has been confirmed, and it has been proven to have significant effects on the treatment of acne, acne scars, and hair loss in clinical practice. No serious side effects were observed during the MTS treatment, and the safety assessment confirmed that it was safe for use.

Abstract

Objectives: The purpose of this study was to analyze the microneedle therapy system (MTS) and its research methods for the past 10 years in Korea. Methods: Data on microneedle therapy system were collected using NDSL, KISS, RISS, and OASIS electronic databases from January 2010 to August 2021. “microneedle,” “derma stamp,” “microneedle therapy system” were used as the keywords. The present study, however, excluded data that were 1) unrelated to the microneedle therapy system, 2) from review/meta/protocol studies, and 3) from overseas studies. Data selected through the primary screening process, animal studies, case reports, and clinical data were included in the analysis. However, information data not related to the microneedle therapy system were excluded from the study. Results: Among the MTS-related papers published from January 2010 to August 2021, 7 animal research, 2 clinical trials, and 10 case studies were published. Based on the research topics, there were 8 papers on skin improvement and skin diseases, 7 papers on hair growth and hair loss, 3 papers on stability, and 1 paper on peripheral facial paralysis. Conclusion: Most of the studies related to MTS focused on skin, hair, and stability. The effect of MTS on hair growth and skin improvement has been confirmed, and it has been proven to have significant effects on the treatment of acne, acne scars, and hair loss in clinical practice. No serious side effects were observed during the MTS treatment, and the safety assessment confirmed that it was safe for use.

참고문헌 (25)

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  8. 이창현, "미세침요법의 모발성장효과", 동의생리병리학회지, 28(1), pp.16~21 (2014), 한의병리학회
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  15. 이기수, "흉터재생침과 미세피부침을 이용한 여드름 흉터의 치험례", Journal of Acupuncture Research, 29(4), pp.81~91 (2012), 대한침구의학회[DOI]
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  18. 허정은, "흉터복원술과 자동 미세침(Auto Microneedle Therapy System, AMTS)을 이용한 여드름 흉터의 치험례", 한방안이비인후피부과학회지, 26(4), pp.127~134 (2013), 대한한방안이비인후피부과학회
  19. 김혜윤, "미세피부침, 절개침법과 봉독 약침 복합 요법의 여드름 흉터 치료 27례 임상 보고", 한방안이비인후피부과학회지, 28(3), pp.101~113 (2015), 대한한방안이비인후피부과학회[DOI]
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  23. Kim BJ, "A study on drug delivery using MTS(Microneedling Therapy System)", Korean Dermatol Assoc Autumn Meet, 58(2), pp.116~ (2006)
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