The Impact of Lower Urinary Tract Symptoms on Quality of Life, Work Productivity, Depressive Symptoms, and Sexuality in Korean Men Aged 40 Years and Older: A Population-Based Survey
2
조회
0
다운로드
7
인용
0
참고문헌
키워드
초록
Purpose: To examine the impact of lower urinary tract symptoms (LUTS) on health-related quality of life (HRQoL) in Korean men aged ≥40 years. Methods: A population-based, cross-sectional door-to-door survey was conducted among men aged ≥40 years. Individuals with LUTS were defined as men reporting at least one LUTS using 2002 International Continence Society definitions. Structured questionnaires were used to assess several dimensions of HRQoL, including generic health status (EuroQoL-five-dimensions questionnaire), work productivity (work productivity and activity impairment questionnaire), depressive symptoms (center for epidemiologic studies depression scale), and sexual health (sexual satisfaction and erectile dysfunction). The impact of LUTS was assessed by comparing several dimensions of HRQoL among men with and without LUTS. Results: Of the 1,842 participants, 1,536 (83.4%) reported having at least one LUTS. The prevalence of LUTS increased with age (78.3% among those aged 40–49 years to 89.6% among those aged 60 years or older). Those with LUTS reported a significantly lower level of generic health status and worse work productivity compared with those without LUTS. Significantly more individuals with LUTS reported having a higher level of major depressive symptoms compared with those without LUTS. Those with LUTS reported worse sexual activity and enjoyment, and were significantly more likely to have erectile dysfunction than those without LUTS. Conclusions: LUTS seem to have a substantial impact on several dimensions of HRQoL in Korean men aged ≥40 years.
Abstract
Purpose: To examine the impact of lower urinary tract symptoms (LUTS) on health-related quality of life (HRQoL) in Korean men aged ≥40 years. Methods: A population-based, cross-sectional door-to-door survey was conducted among men aged ≥40 years. Individuals with LUTS were defined as men reporting at least one LUTS using 2002 International Continence Society definitions. Structured questionnaires were used to assess several dimensions of HRQoL, including generic health status (EuroQoL-five-dimensions questionnaire), work productivity (work productivity and activity impairment questionnaire), depressive symptoms (center for epidemiologic studies depression scale), and sexual health (sexual satisfaction and erectile dysfunction). The impact of LUTS was assessed by comparing several dimensions of HRQoL among men with and without LUTS. Results: Of the 1,842 participants, 1,536 (83.4%) reported having at least one LUTS. The prevalence of LUTS increased with age (78.3% among those aged 40–49 years to 89.6% among those aged 60 years or older). Those with LUTS reported a significantly lower level of generic health status and worse work productivity compared with those without LUTS. Significantly more individuals with LUTS reported having a higher level of major depressive symptoms compared with those without LUTS. Those with LUTS reported worse sexual activity and enjoyment, and were significantly more likely to have erectile dysfunction than those without LUTS. Conclusions: LUTS seem to have a substantial impact on several dimensions of HRQoL in Korean men aged ≥40 years.
참고문헌 (30)
- Abrams P, "The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society", Neurourol Urodyn, 21, pp.167~178 (2002)
- Kupelian V, "Prevalence of lower urinary tract symptoms and effect on quality of life in a racially and ethnically diverse random sample: the Boston Area Community Health (BACH) Survey", Arch Intern Med, 166, pp.2381~2387 (2006)
- Coyne KS, "The impact of overactive bladder, incontinence and other lower urinary tract symptoms on quality of life, work productivity, sexuality and emotional well-being in men and women: results from the EPIC study", BJU Int, 101, pp.1388~1395 (2008)
- Fitzgerald MP, "Beyond the lower urinary tract: the association of urologic and sexual symptoms with common illnesses", Eur Urol, 52, pp.407~415 (2007)
- Fitzgerald MP, "Nocturic frequency is related to severity of obstructive sleep apnea, improves with continuous positive airways treatment", Am J Obstet Gynecol, 194, pp.1399~1403 (2006)
- Welch G, "Quality-of-life impact of lower urinary tract symptom severity: results from the Health Professionals Follow-up Study", Urology, 59, pp.245~250 (2002)
- Chapple CR, "Lower urinary tract symptoms revisited: a broader clinical perspective", Eur Urol, 54, pp.563~569 (2008)
- 김태헌, "The Prevalence of Lower Urinary Tract Symptoms in Korean Men Aged 40 Years or Older: A Population-Based Survey", International Neurourology Journal, 18(3), pp.126~132 (2014), 대한배뇨장애요실금학회
- Irwin DE, "Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study", Eur Urol, 50, pp.1306~1314 (2006)
- 이학민, "Epidemiology of Lower Urinary Tract Symptoms: Emphasis on the Status in Korea", Investigative and Clinical Urology, 55(5), pp.300~308 (2014), 대한비뇨기과학회
- Irwin DE, "Prevalence, severity, and symptom bother of lower urinary tract symptoms among men in the EPIC study: impact of overactive bladder", Eur Urol, 56, pp.14~20 (2009)
- Coyne KS, "The prevalence of lower urinary tract symptoms (LUTS) in the USA, the UK and Sweden: results from the Epidemiology of LUTS (EpiLUTS) study", BJU Int, 104, pp.352~360 (2009)
- Robertson C, "The impact of lower urinary tract symptoms and comorbidities on quality of life: the BACH and UREPIK studies", BJU Int, 99, pp.347~354 (2007)
- Lee YS, "Prevalence of overactive bladder, urinary incontinence, and lower urinary tract symptoms: results of Korean EPIC study", World J Urol, 29, pp.185~190 (2011)
- EuroQol Group, "EuroQol: a new facility for the measurement of health-related quality of life", Health Policy, 16, pp.199~208 (1990)
- 강은정, "EQ-5D를 이용한 건강수준의 가치 평가", 보건경제와 정책연구, 12(2), pp.19~43 (2006), 한국보건경제정책학회
- Reilly MC, "The validity and reproducibility of a work productivity and activity impairment instrument", Pharmacoeconomics, 4, pp.353~365 (1993)
- Radloff LS, "The CES-D scale: a self-report depression scale for research in the general population", Appl Psychol Meas, 1, pp.385~401 (1977)
- Cho MJ, "Diagnostic validity of the CES-D (Korean version) in the assessment of DSM-III-R major depression", J Korean Neuropsychiatr Assoc, 32, pp.381~399 (1993)
- O’Donnell AB, "The validity of a single-question self-report of erectile dysfunction. Results from the Massachusetts Male Aging Study", J Gen Intern Med, 20, pp.515~519 (2005)
- Irwin DE, "Worldwide prevalence estimates of lower urinary tract symptoms, overactive bladder, urinary incontinence and bladder outlet obstruction", BJU Int, 108, pp.1132~1118 (2011)
- Rosen R, "Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7)", Eur Urol, 44, pp.637~649 (2003)
- Rosen RC, "Sexual dysfunction and lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)", Eur Urol, 47, pp.824~837 (2005)
- Wein AJ, "The impact of lower urinary tract symptoms on male sexual health: EpiLUTS", BJU Int, 103(Suppl 3), pp.33~41 (2009)
- Coyne KS, "The burden of lower urinary tract symptoms: evaluating the effect of LUTS on health-related quality of life, anxiety and depression: EpiLUTS", BJU Int, 103(Suppl 3), pp.4~11 (2009)
- Coyne KS, "The impact of overactive bladder on mental health, work productivity and health-related quality of life in the UK and Sweden: results from EpiLUTS", BJU Int, 108, pp.1459~1471 (2011)
- Milsom I, "Effect of bothersome overactive bladder symptoms on health-related quality of life, anxiety, depression, and treatment seeking in the United States: results from EpiLUTS", Urology, 80, pp.90~96 (2012)
- Irwin DE, "Impact of overactive bladder symptoms on employment, social interactions and emotional well-being in six European countries", BJU Int, 97, pp.96~100 (2006)
- Li MK, "Lower urinary tract symptoms and male sexual dysfunction in Asia: a survey of ageing men from five Asian countries", BJU Int, 96, pp.1339~1354 (2005)
- Irwin DE, "Overactive bladder is associated with erectile dysfunction and reduced sexual quality of life in men", J Sex Med, 5, pp.2904~2910 (2008)
