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Effects of Periodontal Treatment on Glycated Hemoglobin A Levels in Patients with Type 2 Diabetes: A Meta-Analysis of Randomized Clinical Trials

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This systematic review aimed to investigate the effects of periodontal treatment on glycated hemoglobin A (HbA1c) levels in patients with type 2 diabetes who develop periodontal disease. The search of the MEDLINE, Embase, CINAHL, and Cochrane Library databases was completed on April 8, 2018. The study design was based on randomized clinical trials. Scaling and root planing was performed for the test group, whereas no periodontal treatment or simple oral training was performed for the control group. The main outcome variable was the change in HbA1c levels. We used the Review Manager statistical analysis software for the quantitative analysis of selected documents. Meta-analysis was performed using the inverse variance estimation method of the fixed-effect model to estimate the effects of periodontal treatment on HbA1c levels in patients with type 2 diabetes. A total of 1,011 documents were searched using search strategies, and 10 documents were included in the meta-analysis. The meta-analysis of the selected literature showed that periodontal treatment significantly reduced the HbA1c levels in patients with type 2 diabetes who develop periodontal disease (mean difference, −0.34; 95% confidence interval, −0.43 to –0.26; p<0.001). This study aimed to investigate the effects of periodontal treatment on HbA1c levels, which can be used as a basis for the increasing management of diabetic complications. To improve the quality of life and reduce the burden of medical expenses for patients with diabetes, periodontal disease management through nonsurgical periodontal treatment, such as scaling and root planing, is necessary.

Abstract

This systematic review aimed to investigate the effects of periodontal treatment on glycated hemoglobin A (HbA1c) levels in patients with type 2 diabetes who develop periodontal disease. The search of the MEDLINE, Embase, CINAHL, and Cochrane Library databases was completed on April 8, 2018. The study design was based on randomized clinical trials. Scaling and root planing was performed for the test group, whereas no periodontal treatment or simple oral training was performed for the control group. The main outcome variable was the change in HbA1c levels. We used the Review Manager statistical analysis software for the quantitative analysis of selected documents. Meta-analysis was performed using the inverse variance estimation method of the fixed-effect model to estimate the effects of periodontal treatment on HbA1c levels in patients with type 2 diabetes. A total of 1,011 documents were searched using search strategies, and 10 documents were included in the meta-analysis. The meta-analysis of the selected literature showed that periodontal treatment significantly reduced the HbA1c levels in patients with type 2 diabetes who develop periodontal disease (mean difference, −0.34; 95% confidence interval, −0.43 to –0.26; p<0.001). This study aimed to investigate the effects of periodontal treatment on HbA1c levels, which can be used as a basis for the increasing management of diabetic complications. To improve the quality of life and reduce the burden of medical expenses for patients with diabetes, periodontal disease management through nonsurgical periodontal treatment, such as scaling and root planing, is necessary.

참고문헌 (44)

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관련 논문AI추천

HbA1c changes in patients with diabetes following periodontal therapy김수환, 김영성, 김원경, 이영규, 이지혜대한치주과학회 · Journal of Periodontal & Implant Science2021 · 제51권 제2호Efficacy of nonsurgical periodontal therapy on glycaemic control in type II diabetic patients: a randomized controlled clinical trialAmit Tirth, Pradeep Shankar Tangade, Ravishankar Lingesha Telgi, Sumit Kumar, Vaibhav Tandon, Vipul Yadav대한치주과학회 · Journal of Periodontal & Implant Science2013 · 제43권 제4호The effect of periodontal and prosthodontic therapy on glycemic control in patients with diabetes김용건, 김학기, 이상규, 이재목, 조진현대한치과보철학회 · The Journal of Advanced of Prosthodontics2019 · 제11권 제5호Effect of scaling and root planing combined with systemic doxycycline therapy on glycemic control in diabetes mellitus subjects with chronic generalized periodontitis: a clinical studyAbhijeet R. Shete, Abhijit N. Gurav, Hitesh M. Desarda, Subodh P. Gaikwad대한치주과학회 · Journal of Periodontal & Implant Science2013 · 제43권 제2호Efficacy of non-surgical treatment accompanied by professional toothbrushing in the treatment of chronic periodontitis in patients with type 2 diabetes mellitus: a randomized controlled clinical trial이재영, 진보형, 최영님, 최윤영대한치주과학회 · Journal of Periodontal & Implant Science2020 · 제50권 제2호한국인 제2형 당뇨병환자에서 치주치료가 당질 및 지질 대사에 미치는 영향김성흡, 김종관, 김창성, 조규성, 채중규, 최성호, 홍지연대한치과의사협회 · 대한치과의사협회지2009 · 제47권 제2호

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