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근위축성 측삭경화증에 대한 한방 치료의 임상선행연구

A pilot clinical study on the Traditional Korean Medicine treatment of Amyotrophic lateral sclerosis

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Objectives: This study was to investigate the effect of Oriental medical treatment on ALS. Methods: We investigated 12 ALS patients which were admitted to Gwang-Ju O.M. hospital from Oct. 14, 2008 to Nov. 14, 2008. All patients were treated by SAAM-acupuncture, herb medication, Bee venom Pharmacopuncture therapy, Needle-embedding therapy, etc. We evaluated patients using the Amyotrophic lateral sclerosis Functional Rating Scale-Revised(ALSFRS-R), Medical Research Council (MRC) Scale. Results: After 30 days, mean ALSFRS-R score of patients was improved from 28.42±7.83 to 29.08±7.99, and mean MRC Scale of patients was improved from 24.79±8.37 to 25.34±8.45. But in both cases, the variation was not statistically significant. After 30 days, mean ALSFRS-R score and mean MRC Scale of patients was more improved in subjects with bulbar-onset, onset age: 51-60yrs., disease duration: 24-48mo. And the results showed partially significant difference. Conclusion: We think that the results of this case be a pilot study that proves the effect of Oriental Medical treatment on ALS.

Abstract

Objectives: This study was to investigate the effect of Oriental medical treatment on ALS. Methods: We investigated 12 ALS patients which were admitted to Gwang-Ju O.M. hospital from Oct. 14, 2008 to Nov. 14, 2008. All patients were treated by SAAM-acupuncture, herb medication, Bee venom Pharmacopuncture therapy, Needle-embedding therapy, etc. We evaluated patients using the Amyotrophic lateral sclerosis Functional Rating Scale-Revised(ALSFRS-R), Medical Research Council (MRC) Scale. Results: After 30 days, mean ALSFRS-R score of patients was improved from 28.42±7.83 to 29.08±7.99, and mean MRC Scale of patients was improved from 24.79±8.37 to 25.34±8.45. But in both cases, the variation was not statistically significant. After 30 days, mean ALSFRS-R score and mean MRC Scale of patients was more improved in subjects with bulbar-onset, onset age: 51-60yrs., disease duration: 24-48mo. And the results showed partially significant difference. Conclusion: We think that the results of this case be a pilot study that proves the effect of Oriental Medical treatment on ALS.

참고문헌 (40)

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