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Sweet Bee Venom 시술후 발생되는 소양감에 대한 임상보고

A Clinical Report of Localized Itching After Treatment with Sweet Bee Venom

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Objectives : This study is to report the percentage of localized itching which occurred, when we injected to patients with Sweet Bee Venom(Sweet BV). Methods : We investigated 374 patients who had injected with Sweet BV in our clinic from February 15. 2009 to April 30, 2010. We checked the number and percentage of patients who occured localized itching on injection area. Then we analyzed those according to times in treatment, the body parts of injection and treatment dosage. Results and Conclusion : Localized itching was lower by 1.60% in the first treatment with Sweet BV. However localized itching was 12.83% in the whole course of treatment, which showed a similar incidence of 13% in Bee Venom. Therefore it can be interpreted that Sweet BV may help suppress the immune responses such as itching in the initial treatment, but the occurrence of local immune responses of Sweet BV may be similar to that of Bee Venom in continued treatment. We suppose that we should be careful of the occurrence of local immune responses as Bee Venom at least until the fourth treatment in clinical application with Sweet BV, although localized itching did not occur in the first treatment. Also we should be careful of treatment with Sweet BV in body parts,such as wrist, hand, chest and abdominal, because the percentage of localized itching was relatively high in those parts.

Abstract

Objectives : This study is to report the percentage of localized itching which occurred, when we injected to patients with Sweet Bee Venom(Sweet BV). Methods : We investigated 374 patients who had injected with Sweet BV in our clinic from February 15. 2009 to April 30, 2010. We checked the number and percentage of patients who occured localized itching on injection area. Then we analyzed those according to times in treatment, the body parts of injection and treatment dosage. Results and Conclusion : Localized itching was lower by 1.60% in the first treatment with Sweet BV. However localized itching was 12.83% in the whole course of treatment, which showed a similar incidence of 13% in Bee Venom. Therefore it can be interpreted that Sweet BV may help suppress the immune responses such as itching in the initial treatment, but the occurrence of local immune responses of Sweet BV may be similar to that of Bee Venom in continued treatment. We suppose that we should be careful of the occurrence of local immune responses as Bee Venom at least until the fourth treatment in clinical application with Sweet BV, although localized itching did not occur in the first treatment. Also we should be careful of treatment with Sweet BV in body parts,such as wrist, hand, chest and abdominal, because the percentage of localized itching was relatively high in those parts.

참고문헌 (13)

  1. Science Commitee of Korean Pharmacoputure Institute, "Pharmacopuncturology", Elsvier Korea, 167~199 (2008)
  2. 최영권, "Gel filtration chromatography와 propionic acid", urea polyacrylamide gel electrophoresis를 이용한 봉독 성분의 분리, 2006, pp.9(2), 105~111[DOI]
  3. 안중철, "봉독과 Sweet Bee Venom의 항균 및 항산화능 비교연구", 대한약침학회지, 9(3), pp.97~104 (2006), 대한약침학회
  4. 임청산, "Sweet BV의 침감비교 연구", 대한약침학회지, 11(2), pp.55~62 (2008), 대한약침학회
  5. Kwon KR, "The study of the introduction of Bee venom Acupuncture , Biochemistry and Pharmachology have been obtained the following results", The Journal of Korea Acupucture & Moxibustion Society, 11(1), pp.159~171 (1994)
  6. 나원민, "Sweet Bee Venom과 봉약침의 퇴행성 슬관절염에 대한 통증감소효과와 Allergy 반응 비교연구", 대한약침학회지, 10(2), pp.47~55 (2007), 대한약침학회
  7. Hwang YJ, "Clinical Study of Anaphylaxis on Bee-Venom Acupuncture", The Journal of Korea Acupucture & Moxibustion Society, 17(4), pp.149~159 (2000)
  8. 윤현민, "봉약침요법으로 발생한 Anaphylaxis에 대한 임상보고", 대한침구학회지, 22(4), pp.179~188 (2005), 대한침구학회
  9. Kwon KR, "The Clinical Observation of Immune Response by Korean Bee Benom Therapy", The Journal of Korean Acupucture & Moxibustion Society, 17(1), pp.169~174 (2000)
  10. Barbara & Rudolf, "Chemistry and Pharmacology of Honey Bee Venom", pp.329~402 (1986), Academic Press
  11. Schmidt J.O, "Allergy to hymenoptera venoms: in Piek T. Ed, Venoms of the hymenoptera", pp.510~518 (1986), Academic Press
  12. 이진선, "봉약침(Bee Venom)과 Sweet Bee Venom의 Allergy 반응에 대한 비교연구", 대한약침학회지, 9(3), pp.61~77 (2006), 대한약침학회
  13. 권기록, "Sweet BV의 성분분석과 항체역가 및 allergy 반응에 대한 임상적 연구", 대한약침학회지, 9(2), pp.79~86 (2006), 대한약침학회

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