자일리톨의 Streptococcus mutans 억제 효과
Effect of Xylitol on Streptococcus mutans
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To examine whether the effects of chewing gum containing xylitol are purely based on xylitol itself rather than the preventive effects on dental caries based on other constituents or factors, gargling was done using xylitol solution which was diluted in a distilled water. Then, attempts were made to perform an experiment for the bacterial activity of S. mutans depending on the amount of xylitol. Gargling was done using solutions containing xylitol at an amount of 30, 50,60, 70, 80 and 90% with the same methods after 48 hours. When gargling was done using a solution containing xylitol at a volume of 60% in those who experienced dental caries, the bacterial activity of S. mutans was decreased by 35% as compared with the control group. When gargling was done using a solution containing xylitol at a volume of 70%, the bacterial activity of S. mutans was decreased by 80% as compared with the control group. These results indicate that there was a significant difference between the two groups (p<0.05). Besides, similar result appeared in those who did not experience dental caries(p<0.05). Based on the above results, under the hypothesis that the effects of xylitol contained in a chewing gum were not associated with other constituents, it is presumed that the amount of xylitol at a ratio of > 70%is effective in reducing the bacterial activity of S. mutans with no respect to experiences of dental caries. But we need an another experiment to confirm whether this result is due to xylitol's effect or not.
Abstract
To examine whether the effects of chewing gum containing xylitol are purely based on xylitol itself rather than the preventive effects on dental caries based on other constituents or factors, gargling was done using xylitol solution which was diluted in a distilled water. Then, attempts were made to perform an experiment for the bacterial activity of S. mutans depending on the amount of xylitol. Gargling was done using solutions containing xylitol at an amount of 30, 50,60, 70, 80 and 90% with the same methods after 48 hours. When gargling was done using a solution containing xylitol at a volume of 60% in those who experienced dental caries, the bacterial activity of S. mutans was decreased by 35% as compared with the control group. When gargling was done using a solution containing xylitol at a volume of 70%, the bacterial activity of S. mutans was decreased by 80% as compared with the control group. These results indicate that there was a significant difference between the two groups (p<0.05). Besides, similar result appeared in those who did not experience dental caries(p<0.05). Based on the above results, under the hypothesis that the effects of xylitol contained in a chewing gum were not associated with other constituents, it is presumed that the amount of xylitol at a ratio of > 70%is effective in reducing the bacterial activity of S. mutans with no respect to experiences of dental caries. But we need an another experiment to confirm whether this result is due to xylitol's effect or not.
참고문헌 (25)
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