A case of hepatocellular carcinoma in the caudate lobe successfully treated by transcatheter arterial chemoembolization using drug-eluting beads
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Hepatocellular carcinoma (HCC) in the caudate lobe remains one of the most intricate locations where various treatments tend to pose problems with regard to the optimal approach. Surgical resection has been regarded as the most effective treatment; however, isolated resection of the caudate lobe is strenuous and associated with a high rate of early recurrence. Percutaneous ablation might be technically difficult or impossible to perform due to the deep location of tumors and adjacent large vessels. Treatment with drug-eluting beads (DEB) can potentially enhance the therapeutic efficacy for patients with unresectable HCC by drawing on the slower, more consistent drug delivery process. We described a case of a 62-year-old man with HCC in the caudate lobe who was successfully treated by DEB.
Abstract
Hepatocellular carcinoma (HCC) in the caudate lobe remains one of the most intricate locations where various treatments tend to pose problems with regard to the optimal approach. Surgical resection has been regarded as the most effective treatment; however, isolated resection of the caudate lobe is strenuous and associated with a high rate of early recurrence. Percutaneous ablation might be technically difficult or impossible to perform due to the deep location of tumors and adjacent large vessels. Treatment with drug-eluting beads (DEB) can potentially enhance the therapeutic efficacy for patients with unresectable HCC by drawing on the slower, more consistent drug delivery process. We described a case of a 62-year-old man with HCC in the caudate lobe who was successfully treated by DEB.
참고문헌 (20)
- El-Serag HB, "Diagnosis and treatment of hepatocellular carcinoma", Gastroenterology, 134, pp.1752~1763 (2008)
- Llovet JM, "Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival", Hepatology, 37, pp.429~442 (2003)
- Hong K, "New intra-arterial drug delivery system for the treatment of liver cancer: preclinical assessment in a rabbit model of liver cancer", Clin Cancer Res, 12, pp.2563~2567 (2006)
- Abdalla EK, "The caudate lobe of the liver: implications of embryology and anatomy for surgery", Surg Oncol Clin N Am, 11, pp.835~848 (2002)
- Takayasu K, "Clinical and radiologic features of hepatocellular carcinoma originating in the caudate lobe", Cancer, 58, pp.1557~1562 (1986)
- Liu P, "Prognostic factors in the surgical treatment of caudate lobe hepatocellular carcinoma", World J Gastroenterol, 16, pp.1123~1128 (2010)
- Shimada M, "Characteristics of hepatocellular carcinoma originating in the caudate lobe", Hepatology, 19, pp.911~915 (1994)
- Hawkins WG, "Caudate hepatectomy for cancer: a single institution experience with 150 patients", J Am Coll Surg, 200, pp.345~352 (2005)
- Tanaka S, "Surgical outcome of patients with hepatocellular carcinoma originating in the caudate lobe", Am J Surg, 190, pp.451~455 (2005)
- Utsunomiya T, "High dorsal resection for recurrent hepatocellular carcinoma originating in the caudate lobe", Surg Today, 39, pp.829~832 (2009)
- Peng ZW, "Percutaneous radiofrequency ablation for the treatment of hepatocellular carcinoma in the caudate lobe", Eur J Surg Oncol, 34, pp.166~172 (2008)
- Ishiko T, "Radiofrequency ablation with hand-assisted laparoscopic surgery for the treatment of hepatocellular carcinoma in the caudate lobe", Surg Laparosc Endosc Percutan Tech, 18, pp.272~276 (2008)
- Kim HO, "Intraoperative radiofrequency ablation with or without tumorectomy for hepatocellular carcinoma in locations difficult for a percutaneous approach", Hepatobiliary Pancreat Dis Int, 8, pp.591~596 (2009)
- Lewis AL, "DC bead: in vitro characterization of a drug-delivery device for transarterial chemoembolization", J Vasc Interv Radiol, 17, pp.335~342 (2006)
- Varela M, "Chemoembolization of hepatocellular carcinoma with drug eluting beads: efficacy and doxorubicin pharmacokinetics", J Hepatol, 46, pp.474~481 (2007)
- Poon RT, "A phase I", II trial of chemoembolization for hepatocellular carcinoma using a novel intra-arterial drug-eluting bead, 2007, pp.5, 1100~1108
- Malagari K, "Transarterial chemoembolization of unresectable hepatocellular carcinoma with drug eluting beads: results of an open-label study of 62 patients", Cardiovasc Intervent Radiol, 31, pp.269~280 (2008)
- Lammer J, "Prospective randomized study of doxorubicin-eluting-bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V study", Cardiovasc Intervent Radiol, 33, pp.41~52 (2010)
- Terayama N, "Subsegmental transcatheter arterial embolization for hepatocellular carcinoma in the caudate lobe", J Vasc Interv Radiol, 9, pp.501~508 (1998)
- Decaens T, "Impact of pretransplantation transarterial chemoembolization on survival and recurrence after liver transplantation for hepatocellular carcinoma", Liver Transpl, 11, pp.767~775 (2005)
