간염 양상으로 나타난 원발성 간림프종 1예
A Case of Primary Hepatic Lymphoma Mimicking Hepatitis
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Abstract
We report here on a case of non-Hodgkin’s lymphoma in which liver involvement was the predominant clinical manifestation. A healthy 44-year-old man presented with upper abdominal pain, hepatosplenomegaly, thrombocytopenia, elevated AST, ALT and bilirubin, and marked elevation of lactate dehydrogenase and alkaline phosphatase. The abdominal CT scan showed only diffuse hepatosplenomegaly and uneven contrast enhancement of the spleen without any definite mass of the liver and spleen. US-guided aspiration biopsy of liver and the histologic examination confirmed a diagnosis of non-Hodgkin’s lymphoma, the diffuse large B cell type. Bone marrow biopsy showed the infiltration of malignant lymphoma cells. PET-CT showed an increased FDG uptake of the liver, spleen and long bones. The patient was treated with combination regimen of cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy. Even in the absence of a mass lesion or lymphadenopathy, primary hepatic or hepatosplenic lymphoma should be considered in differential diagnosis of hepatitis or liver cirrhosis, especially for patients with diffuse hepatosplenomegaly and markedly elevated LDH.
참고문헌 (16)
- "Primary hepatic lymphoma:Favorable outcome after combination chemotherapy", 92, pp.2023~2029 (2001)
- "Primary Malignant Lymphoma of the Liver-Report of a case", 21, pp.285~290 (1987)
- "A case of primary lymphoma of the liver", 22, pp.460~466 (1990)
- "Primary MALT(mucosa associated lymphoid tissue)type lymphoma of the liver", 31, pp.1317~1319 (1997)
- "A case of primary low- grade hepatic B-cell lymphoma of mucosa-associated lymphoid tissue(MALT)-Type", 31, pp.547~552 (1998)
- "A case of primary T cell lymphoma of the liver presented as FUO", 60, pp.260~265 (2001)
- "A case of primary hepatic lymphoma developed in a patient with chronic hepatitis B", 38, pp.440~443 (2001)
- "Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome:a case report", 14, pp.671~674 (1999)
- "Malignant lymphoma imitating hepatitis", 71, pp.2639~2646 (1993)
- "Malignant lymphoma can present as hepatobiliary disease", 78, pp.2011~2019 (1996)
- "Acute hepatic failure due to hepatosplenic B-cell non-Hodgkin's lymphoma in a patient infected with hepatitis C virus", 33, pp.880~885 (1998)
- "Fulminant hepatosplenic B cell lymphoma in a young patient with HCV-chronic hepatitis", 12, pp.1005~1006 (1998)
- "Primary hepatic non-Hodgkin's lymphomas:Case report and review of the literature", 98, pp.2789~2793 (2003)
- "Primary lymphoma of the liver in the acquired immunodeficiency syndrome", 110, pp.553~555 (1986)
- "Primary non-Hodgkin's lymphoma of the liver", 29, pp.293~299 (1998)
- "Primary non-Hodgkin's lymphoma of the liver", 29, pp.293~299 (1998)