피부 결절로 나타난 재발 간세포암종의 피부전이 1예
A Case of Metastatic Cutaneous Nodules of Recurrent Hepatocellular Carcinoma
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초록
간세포암종의 일반적인 전이 부위는 폐, 복강, 부신 및 뼈이며 피부전이는 매우 드물다. 간세포암종이 우리나라에서 세 번째로 흔한 암종이지만 보고된 간세포암종의 피부전이는 매우 드물다. 내부 장기의 암종으로부터 피부전이는 다양한 병기에서 나타날 수 있으며 피부병변의 성장 양상은 비특이적이고 다양하기 때문에 다른 피부병변과 감별진단하기 위해서 조직검사를 고려해야 한다. 저자들은 재발 간세포암종의 피부전이를 면역조직화학염색을 이용한 조직검사를 통해 확진한 사례를 보고한다.
Abstract
Common metastaic sites of hepatocellular carcinoma include lung, peritoneum, adrenal gland and bone, but rarely, skin can be metastatic sites. Although hepatocellular carcinoma is the third commonest malignancy in Korea, cutaneous metastasis from hepatocellular carcinoma was rarely reported. Cutaneous metastasis from malignant neoplasm of the internal organ occur at the variable stage and the growth pattern of cutaneous lesions is nonspecific and various, so the differential diagnosis of skin lesions must be considered to other malignant condition. We report a case of cutaneous metastasis from recurrent hepatocellular carcinoma that was confirmed by skin biopsy with immunohistochemical stain. (Korean J Hepatol 2007;13:234-238)
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