Pure red-cell aplasia and autoimmune hemolytic anemia in a patient with acute hepatitis A
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Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepaticmanifestation of acute hepatitis A (AHA). We report herein a case of AHA complicated by both PRCA and AIHA. A 49-yearoldfemale with a diagnosis of AHA presented with severe anemia (hemoglobin level, 6.9 g/dL) during her clinicalcourse. A diagnostic workup revealed AIHA and PRCA as the cause of the anemia. The patient was treated with an initialtransfusion and corticosteroid therapy. Her anemia and liver function test were completely recovered by 9 monthsafter the initial presentation. We review the clinical features and therapeutic strategies for this rare case of extrahepaticmanifestation of AHA.
Abstract
Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepaticmanifestation of acute hepatitis A (AHA). We report herein a case of AHA complicated by both PRCA and AIHA. A 49-yearoldfemale with a diagnosis of AHA presented with severe anemia (hemoglobin level, 6.9 g/dL) during her clinicalcourse. A diagnostic workup revealed AIHA and PRCA as the cause of the anemia. The patient was treated with an initialtransfusion and corticosteroid therapy. Her anemia and liver function test were completely recovered by 9 monthsafter the initial presentation. We review the clinical features and therapeutic strategies for this rare case of extrahepaticmanifestation of AHA.
참고문헌 (16)
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