Current status and perspective on molecular targets and therapeutic intervention strategy in hepatic ischemia- reperfusion injury

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참고문헌 (155)

1. Ye L, "Effect of hepatic macrophage polarization and apoptosis on liver ischemia and reperfusion injury during liver transplantation", Front Immunol, 11, pp.1193~ (2020)
2. Devarbhavi H, "Global burden of liver disease : 2023 update", J Hepatol, 79, pp.516~537 (2023)
3. Zhou J, "Nacetylgalactosaminyltransferase-4 protects against hepatic ischemia", reperfusion injury by blocking apoptosis signalregulating kinase 1 N-terminal dimerization, 2022, pp.75, 1446~1460
4. Yuan D, "Blue light reduces organ injury from ischemia and reperfusion", Proc Natl Acad Sci U S A, 113, pp.5239~5244 (2016)
5. Peralta C, "Hepatic ischemia and reperfusion injury : effects on the liver sinusoidal milieu", J Hepatol, 59, pp.1094~1106 (2013)
6. Bavarsad K, "Protective effects of curcumin against ischemiareperfusion injury in the liver", Pharmacol Res, 141, pp.53~62 (2019)
7. Pantazi E, "Advances in treatment strategies for ischemia reperfusion injury", Expert Opin Pharmacother, 17, pp.169~179 (2016)
8. Jaeschke H, "Apoptosis versus oncotic necrosis in hepatic ischemia", reperfusion injury, 2003, pp.125, 1246~1257
9. Peralta C, "Hepatic ischemia and reperfusion injury : effects on the liver sinusoidal milieu", J Hepatol, 59, pp.1094~1106 (2013)
10. Xie Y, "Ferroptosis : process and function", Cell Death Differ, 23, pp.369~379 (2016)
11. Tang SP, "Reactive oxygen species induce fatty liver and ischemia-reperfusion injury by promoting inflammation and cell death", Front Immunol, 13, pp.870239~ (2022)
12. Liu H, "New insights in mechanisms and therapeutics for short-and long-term impacts of hepatic ischemia reperfusion injury post liver transplantation", Int J Mol Sci, 22, pp.8210~ (2021)
13. Vartak R, "Respiratory supercomplexes : structure, function and assembly", Protein Cell, 4, pp.582~590 (2013)
14. Schusdziarra C, "Methylationcontrolled J-protein MCJ acts in the import of proteins into human mitochondria", Hum Mol Genet, 22, pp.1348~1357 (2013)
15. Goikoetxea-Usandizaga N, "Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals", Hepatology, 75, pp.550~566 (2022)
16. Teixeira da Silva R, "PEG35 as a preconditioning agent against hypoxia", reoxygenation injury, 2022, pp.23, 1156~
17. Shang L, "SS-31Protects liver from ischemia-reperfusion injury via modulating macrophage polarization", Oxid Med Cell Longev, 2021, pp.6662156~ (2021)
18. Zeng H, "Copper deficiency decreases complex IV but not complex I, II, III, or V in the mitochondrial respiratory chain in rat heart", J Nutr, 137, pp.14~18 (2007)
19. Zhuang R, "Virus-mimicking liposomal system based on dendritic lipopeptides for efficient prevention ischemia", reperfusion injury in the mouse liver, 2021, pp.10, 215~222
20. Frye RA, "Characterization of five human cDNAs with homology to the yeast SIR2 gene : Sir2-like proteins(sirtuins)metabolize NAD and may have protein ADP-ribosyltransferase activity", Biochem Biophys Res Commun, 260, pp.273~279 (1999)
21. He S, "NAD+ameliorates endotoxin-induced acute kidney injury in a sirtuin1-dependent manner via GSK-3β", Nrf2 signalling pathway, 2022, pp.26, 1979~1993
22. Teodoro JS, "Indirubin and NAD+ prevent mitochondrial ischaemia", reperfusion damage in fatty livers, 2018, pp.48, e12932~
23. Schlegel A, "Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation", EBioMedicine, 60, pp.103014~ (2020)
24. Lin J, "Mitochondrial dynamics and mitophagy in cardiometabolic disease", Front Cardiovasc Med, 9, pp.917135~ (2022)
25. Du YD, "N6-methyladenosine demethylase FTO impairs hepatic ischemia-reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation", Cell Death Dis, 12, pp.442~ (2021)
26. Huang J, "Inhibition of Drp1 SUMOylation by ALR protects the liver from ischemia-reperfusion injury", Cell Death Differ, 28, pp.1174~1192 (2021)
27. Sun X, "A negative feedback regulation of MTORC1 activity by the lysosomal Ca2+ channel MCOLN1(mucolipin 1)using a CALM(calmodulin)-dependent mechanism", Autophagy, 14, pp.38~52 (2018)
28. Hanna RA, "Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin", Nature, 456, pp.409~412 (2008)
29. Flores-Toro J, "Critical roles of calpastatin in ischemia", reperfusion injury in aged livers, 2021, pp.10, 1863~
30. Kong WN, "Augmenter of liver regeneration-mediated mitophagy protects against hepatic ischemia", reperfusion injury, 2022, pp.22, 130~143
31. Xu M, "DJ-1 deficiency in hepatocytes improves liver ischemia-reperfusion injury by enhancing mitophagy", Cell Mol Gastroenterol Hepatol, 12, pp.567~584 (2021)
32. An W, "Effect of metformin on myocardial injury induced by hepatic ischemia-reperfusion in rats", Front Pharmacol, 13, pp.822743~ (2022)
33. Zhang X, "Antioxidant and C5a-blocking strategy for hepatic ischemiareperfusion injury repair", J Nanobiotechnology, 19, pp.107~ (2021)
34. Zhang YP, "New progress in understanding roles of nitric oxide during hepatic ischemia-reperfusion injury", World J Hepatol, 14, pp.504~515 (2022)
35. Ferreira-Silva M, "Quercetin liposomal nanoformulation for ischemia and reperfusion injury treatment", Pharmaceutics, 14, pp.104~ (2022)
36. Hide D, "Ischemia", reperfusion injury in the aged liver : The importance of the sinusoidal endothelium in developing therapeutic strategies for the elderly, 2020, pp.75, 268~277
37. Wu J, "Ferulic acid ameliorates hepatic inflammation and fibrotic liver injury by inhibiting PTP1B activity and subsequent promoting AMPK phosphorylation", Front Pharmacol, 12, pp.754976~ (2021)
38. Anavi S, "iNOS as a metabolic enzyme under stress conditions", Free Radic Biol Med, 146, pp.16~35 (2020)
39. Mu J, "Protective effect of platinum nano-antioxidant and nitric oxide against hepatic ischemia-reperfusion injury", Nat Commun, 13, pp.2513~ (2022)
40. Shen Y, "Myricitrin pretreatment ameliorates mouse liver ischemia reperfusion injury", Int Immunopharmacol, 89, pp.107005~ (2020)
41. Ma Q, "Role of nrf2 in oxidative stress and toxicity", Annu Rev Pharmacol Toxicol, 53, pp.401~426 (2013)
42. Li Z, "Protective effects of fisetin on hepatic ischemia-reperfusion injury through alleviation of apoptosis and oxidative stress", Arch Med Res, 52, pp.163~173 (2021)
43. Yi Z, "Immune-responsive gene 1", itaconate activates nuclear factor erythroid 2-related factor 2 in hepatocytes to protect against liver ischemia-reperfusion injury, 2020, pp.72, 1394~1411
44. Yu Q, "Veratric acid alleviates liver ischemia", reperfusion injury by activating the Nrf2 signaling pathway, 2021, pp.101, 108294~
45. Trocha M, "Sitagliptin modulates oxidative, nitrative and halogenative stress and inflammatory response in rat model of hepatic ischemia-reperfusion", Antioxidants(Basel), 10, pp.1168~ (2021)
46. Mao Y, "p21-activated kinase 4 inhibition protects against liver ischemia", reperfusion injury : Role of nuclear factor erythroid 2-related factor 2 phosphorylation, 2022, pp.76, 345~356
47. Yuan B, "Gastrodin pretreatment protects liver against ischemia-reperfusion injury via activation of the Nrf2", HO-1 pathway, 2020, pp.48, 1159~1178
48. Chen Y, "Kaempferol from penthorum chinense pursh attenuates hepatic ischemia", reperfusion injury by suppressing oxidative stress and inflammation through activation of the Nrf2, Front Pharmacol, pp.2022, 13[DOI]
49. Tong G, "FGF18alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1", Nrf2 signaling pathway in male mice, 2023, pp.14, 6107~
50. Feng R, "Nrf2 activation drive macrophages polarization and cancer cell epithelial-mesenchymal transition during interaction", Cell Commun Signal, 16, pp.54~ (2018)
51. Kim TH, "NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1α", Cancer Res, 71, pp.2260~2275 (2011)
52. Zhang X, "Hypoxiainducible factor-1alpha protects the liver against ischemiareperfusion injury by regulating the A2B adenosine receptor", Bioengineered, 12, pp.3737~3752 (2021)
53. Dery KJ, "Alternative splicing of CEACAM1 by hypoxia-inducible factor-1α enhances tolerance to hepatic ischemia in mice and humans", Sci Transl Med, 15, pp.eadf2059~ (2023)
54. Wang Q, "Role of XBP1 in regulating the progression of non-alcoholic steatohepatitis", J Hepatol, 77, pp.312~325 (2022)
55. Li K, "Chlorogenic acid alleviates hepatic ischemia-reperfusion injury by inhibiting oxidative stress, inflammation, and mitochondria-mediated apoptosis in vivo and in vitro", Inflammation, 46, pp.1061~1076 (2023)
56. Saleh H, "Chitosan protects liver against ischemia-reperfusion injury via regulating Bcl-2", Bax, TNF-αand TGF-β expression, 2020, pp.164, 1565~1574
57. Wang YL, "Hepatoprotective effects of sevoflurane against hepatic ischemia-reperfusion injury by regulating microRNA-124-3p-mediated TRAF3", CREB axis, 2022, pp.8, 105~
58. Hu HH, "New insights into TGF-β", Smad signaling in tissue fibrosis, 2018, pp.292, 76~83
59. Yang Y, "Ghrelin ameliorates transformation of hepatic ischemia-reperfusion injury to liver fibrosis by blocking Smad and ERK signalling pathways, and promoting anti-inflammation and anti-oxidation effects", Transpl Immunol, 73, pp.101597~ (2022)
60. Pan WM, "miR-210 Participates in hepatic ischemia reperfusion injury by forming a negative feedback loop with SMAD4", Hepatology, 72, pp.2134~2148 (2020)
61. Zheng X, "hsa-miR-34a-5p Ameliorates hepatic ischemia", reperfusion injury via targeting HNF4α, 2022, pp.33, 596~605
62. Zhu S, "Hippo(YAP)-autophagy axis protects against hepatic ischemiareperfusion injury through JNK signaling", Chin Med J(Engl), 137, pp.657~668 (2024)
63. Guo WZ, "Sixtransmembrane epithelial antigen of the prostate 3 deficiency in hepatocytes protects the liver against ischemia-reperfusion injury by suppressing transforming growth factor-β-activated kinase 1", Hepatology, 71, pp.1037~1054 (2020)
64. Chen SY, "Tripartite motif-containing 27 attenuates liver ischemia", reperfusion injury by suppressing transforming growth factor β-activated kinase 1(TAK1)by TAK1 binding protein 2, Hepatology, pp.2021, 73[DOI]
65. Zhang JK, "Regulator of G-protein signaling 14 protects the liver from ischemia-reperfusion injury by suppressing TGF-β-activated kinase 1 activation", Hepatology, 75, pp.338~352 (2022)
66. Ding MJ, "E3 ubiquitin ligase ring finger protein 5 protects against hepatic ischemia reperfusion injury by mediating phosphoglycerate mutase family member 5 ubiquitination", Hepatology, 76, pp.94~111 (2022)
67. Zhou J, "Nacetylgalactosaminyltransferase-4 protects against hepatic ischemia", reperfusion injury by blocking apoptosis signalregulating kinase 1 N-terminal dimerization, 2022, pp.75, 1446~1460
68. Chen X, "β-Arrestin-2 attenuates hepatic ischemia-reperfusion injury by activating PI3K", Akt signaling, 2020, pp.13, 2251~2263
69. Tang D, "Maresin 1 protects the liver against ischemia", reperfusion injury via the ALXR, Mol Med, pp.2021, 27[DOI]
70. Li Y, "MicroRNA-142-3p attenuates hepatic ischemia", reperfusion injury via targeting of myristoylated alanine-rich C-kinase substrate, 2020, pp.156, 104783~
71. Wang M, "Methyl eugenol attenuates liver ischemia reperfusion injury via activating PI3K", Akt signaling, 2021, pp.99, 108023~
72. Ding J, "Cordycepin Protects against Hepatic Ischemia", Reperfusion Injury via Inhibiting MAPK, Mediators Inflamm, pp.2022, 2022[DOI]
73. Kim HJ, "Carbon monoxide protects against hepatic ischemia", reperfusion injury by modulating the miR-34a, Biochim Biophys Acta, pp.2015, 1852[DOI]
74. Samuvel DJ, "LP342, a novel histone deacetylase inhibitor, decreases nitro-oxidative stress, mitochondrial dysfunction and hepatic ischaemia", reperfusion injury in mice, 2023, pp.2, rqad013~
75. Luo J, "PIAS1 Alleviates hepatic ischemia-reperfusion injury in mice through a mechanism involving NFATc1 SUMOylation", Dis Markers, 2022, pp.4988539~ (2022)
76. Burdette BE, "Gasdermin D in pyroptosis", Acta Pharm Sin B, 11, pp.2768~2782 (2021)
77. Kadono K, "Myeloid Ikaros-SIRT1 signaling axis regulates hepatic inflammation and pyroptosis in ischemia-stressed mouse and human liver", J Hepatol, 76, pp.896~909 (2022)
78. Szabo G, "Inflammasome activation and function in liver disease", Nat Rev Gastroenterol Hepatol, 12, pp.387~400 (2015)
79. Wu Y, "Dexmedetomidine alleviates hepatic ischaemia-reperfusion injury via the PI3K", AKT, J Cell Mol Med, pp.2021, 25[DOI]
80. Kolachala VL, "Ischemia reperfusion injury induces pyroptosis and mediates injury in steatotic liver thorough Caspase 1 activation", Apoptosis, 26, pp.361~370 (2021)
81. Yamada N, "Iron overload as a risk factor for hepatic ischemiareperfusion injury in liver transplantation : Potential role of ferroptosis", Am J Transplant, 20, pp.1606~1618 (2020)
82. Li C, "Gp78 deficiency in hepatocytes alleviates hepatic ischemia-reperfusion injury via suppressing ACSL4-mediated ferroptosis", Cell Death Dis, 14, pp.810~ (2023)
83. Zhang Y, "Radix Rehmanniae Praeparata aqueous extract improves hepatic ischemia", reperfusion injury by restoring intracellular iron homeostasis, 2023, pp.21, 1~17
84. Roh JS, "Damage-associated molecular patterns in inflammatory diseases", Immune Netw, 18, pp.e27~ (2018)
85. Du Y, "The dietary supplement γ-oryzanol attenuates hepatic ischemia reperfusion injury via inhibiting endoplasmic reticulum stress and HMGB1", NLRP3 inflammasome, 2021, pp.2021, 4628050~
86. Ma T, "Protective effect of pinocembrin from Penthorum chinense Pursh on hepatic ischemia reperfusion injury via regulating HMGB1", TLR4 signal pathway, 2023, pp.37, 181~194
87. Le Bastard Q, "The effects of inulin on gut microbial composition : a systematic review of evidence from human studies", Eur J Clin Microbiol Infect Dis, 39, pp.403~413 (2020)
88. Kawasoe J, "Propionic acid, induced in gut by an inulin diet, suppresses inflammation and ameliorates liver ischemia and reperfusion injury in mice", Front Immunol, 13, pp.862503~ (2022)
89. Kawasoe J, "The lectin-like domain of thrombomodulin is a drug candidate for both prophylaxis and treatment of liver ischemia and reperfusion injury in mice", Am J Transplant, 21, pp.540~551 (2021)
90. Coughlin SR, "Thrombin signalling and protease-activated receptors", Nature, 407, pp.258~264 (2000)
91. Noguchi D, "The impact of dabigatran treatment on sinusoidal protection against hepatic ischemia", reperfusion injury in mice, 2021, pp.27, 363~384
92. Sosa RA, "Disulfide high-mobility group box 1 drives ischemiareperfusion injury in human liver transplantation", Hepatology, 73, pp.1158~1175 (2021)
93. Rao J, "Nogo-B is a key mediator of hepatic ischemia and reperfusion injury", Redox Biol, 37, pp.101745~ (2020)
94. Bai C, "Ac2‑26 alleviates hepatic ischemia‑reperfusion injury based on inhibiting the positive feedback loop of HMGB1", TLR4, neutrophils, pp.Exp Ther Med, 2022[DOI]
95. Gendy AM, "Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia", reperfusion-induced lesion through modulation of HMGB1, NF-κB signaling and autophagy, pp.Biomed Pharmacother, 2022[DOI]
96. Liang C, "Silencing lncRNA KCNQ1OT1 reduced hepatic ischemia reperfusion injury-induced pyroptosis by regulating miR-142a-3p", HMGB1axis, 2023, pp.478, 1293~1305
97. Jia K, "Acteoside ameliorates hepatic ischemia-reperfusion injury via reversing the senescent fate of liver sinusoidal endothelial cells and restoring compromised sinusoidal networks", Int J Biol Sci, 19, pp.4967~4988 (2023)
98. Terry AQ, "Disulfide-HMGB1 signals through TLR4 and TLR9 to induce inflammatory macrophages capable of innate-adaptive crosstalk in human liver transplantation", Am J Transplant, 23, pp.1858~1871 (2023)
99. Barbier L, "Endogenous interleukin-33 acts as an alarmin in liver ischemia-reperfusion and is associated with injury after human liver transplantation", Front Immunol, 12, pp.744927~ (2021)
100. Zhang HM, "ILC2s expanded by exogenous IL-33 regulate CD45+CD11b+F4", 80high macrophage polarization to alleviate hepatic ischemia-reperfusion injury, 2022, pp.13, 869365~
101. Li S, "Modulation of type I interferon signaling by natural products in the treatment of immunerelated diseases", Chin J Nat Med, 21, pp.3~18 (2023)
102. Li Y, "Chuanxiong Rhizoma extracts prevent cholestatic liver injury by targeting H3K9ac-mediated and cholangiocyte-derived secretory protein PAI-1 and FN", Chin J Nat Med, 21, pp.694~709 (2023)
103. Wang Z, "Activated AXL protects against hepatic ischemia-reperfusion injury by upregulating SOCS-1 expression", Transplantation, 106, pp.1351~1364 (2022)
104. Morsy MA, "Protective mechanisms of telmisartan against hepatic ischemia", reperfusion injury in rats may involve PPARγ-induced TLR4, Biomed Pharmacother, pp.2022, 145[DOI]
105. Zhou W, "Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemiareperfusion injury", Cell Death Dis, 12, pp.211~ (2021)
106. Gendy A, "Morin alleviates hepatic ischemia", reperfusion-induced mischief : In vivo and in silico contribution of Nrf2, TLR4, and NLRP3, 2021, pp.138, 111539~
107. Liu Y, "Salidroside alleviates hepatic ischemia-reperfusion injury during liver transplant in rat through regulating TLR-4", NF-κB, Sci Rep, pp.2022, 12[DOI]
108. Yang X, "The protective effects of dietary Clostridium butyricum supplementation on hepatic ischemia reperfusion injury in rats", Acta Cir Bras, 37, pp.e370904~ (2022)
109. Liu H, "Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation", Cell Death Dis, 13, pp.484~ (2022)
110. Schmitz SM, "Inhaled argon impedes hepatic regeneration after ischemia", reperfusion injury in rats, 2020, pp.21, 5457~
111. Xue Z, "PACAP neuropeptide promotes hepatocellular protection via CREB-KLF4 dependent autophagy in mouse liver ischemia reperfusion injury", Theranostics, 10, pp.4453~4465 (2020)
112. Shi G, "Hepatic interferon regulatory factor 8 expression mediates liver ischemia", reperfusion injury in mice, 2021, pp.192, 114728~
113. Krzystek-Korpacka M, "Modulation of prostanoids profile and counter-regulation of SDF-1α", CXCR4and VIP, Int J Mol Sci, pp.2021, 22[DOI]
114. Chen H, "The role of MLKL in hepatic ischemia-reperfusion injury of alcoholic steatotic livers", Int J Biol Sci, 18, pp.1096~1106 (2022)
115. Qiang X, "Human dermcidin protects mice against hepatic ischemia-reperfusion-induced local and remote inflammatory injury", Front Immunol, 12, pp.821154~ (2022)
116. Yin E, "Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury", Sci Rep, 11, pp.6312~ (2021)
117. Ni X, "Carabin deficiency aggravates hepatic ischemia-reperfusion injury through promoting neutrophil trafficking via ras and calcineurin signaling", Front Immunol, 13, pp.773291~ (2022)
118. Stephan A, "The NET, the trap and the pathogen : neutrophil extracellular traps in cutaneous immunity", Exp Dermatol, 24, pp.161~166 (2015)
119. Guo J, "Histidine-rich glycoprotein alleviates liver ischemia", reperfusion injury in mice with nonalcoholic steatohepatitis, 2021, pp.27, 840~853
120. Wang Y, "Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway", Biomed Pharmacother, 160, pp.114358~ (2023)
121. Yazdani HO, "Exercise training decreases hepatic injury and metastases through changes in immune response to liver ischemia", reperfusion in mice, 2021, pp.73, 2494~2509
122. Wang H, "Macrophage polarization and liver ischemia-reperfusion injury", Int J Med Sci, 18, pp.1104~1113 (2021)
123. Long Y, "Prevention of hepatic ischemia-reperfusion injury by carbohydratederived nanoantioxidants", Nano Lett, 20, pp.6510~6519 (2020)
124. Rao J, "Macrophage nuclear factor erythroid 2-related factor 2 deficiency promotes innate immune activation by tissue inhibitor of metalloproteinase 3-mediated RhoA", ROCK pathway in the ischemic liver, 2022, pp.75, 1429~1445
125. Liang W, "Sulforaphane exerts beneficial immunomodulatory effects on liver tissue via a Nrf2 pathway-related mechanism in a murine model of hemorrhagic shock and resuscitation", Front Immunol, 13, pp.822895~ (2022)
126. Wang YY, "Maslinic acid protects against lipopolysaccharide", d-galactosamine-induced acute liver injury in mice, 2018, pp.119, 49~53
127. Ishikawa H, "STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling", Nature, 455, pp.674~678 (2008)
128. Zhong W, "Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated NLRP3 activation in macrophages", Aging Cell, 19, pp.e13186~ (2020)
129. Wu XY, "STING Induces liver ischemia-reperfusion injury by promoting calciumdependent caspase 1-GSDMD processing in macrophages", Oxid Med Cell Longev, 2022, pp.8123157~ (2022)
130. Nakamoto S, "Lymphangiogenesis and accumulation of reparative macrophages contribute to liver repair after hepatic ischemiareperfusion injury", Angiogenesis, 23, pp.395~410 (2020)
131. Wang L, "Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution", Cell Death Dis, 12, pp.589~ (2021)
132. Yang X, "Single-cell profiling reveals distinct immune phenotypes that contribute to ischaemia-reperfusion injury after steatotic liver transplantation", Cell Prolif, 54, pp.e13116~ (2021)
133. Sheng M, "CD47-mediated Hedgehog", SMO, Hepatology, pp.2021, 74[DOI]
134. Yu J, "Hepatocyte TLR4 triggers inter-hepatocyte Jagged1", Notch signaling to determine NASH-induced fibrosis, 2021, pp.13, eabe1692~
135. Jin Y, "Jagged1-mediated myeloid Notch1 signaling activates HSF1", Snail and controls NLRP3 inflammasome activation in liver inflammatory injury, 2020, pp.17, 1245~1256
136. Li SL, "Liraglutide attenuates hepatic ischemia-reperfusion injury by modulating macrophage polarization", Front Immunol, 13, pp.869050~ (2022)
137. Huang Z, "Inhibition of miR-450b-5p ameliorates hepatic ischemia", reperfusion injury via targeting CRYAB, 2020, pp.11, 455~
138. Zhou H, "TGR5", Cathepsin E signaling regulates macrophage innate immune activation in liver ischemia and reperfusion injury, 2021, pp.21, 1453~1464
139. Zito G, "Human amnion-derived mesenchymal stromal", stem cells preconditioning inhibits inflammation and apoptosis of immune and parenchymal cells in an in vitro model of liver ischemia, Cells, pp.2022, 11[DOI]
140. Dery KJ, "Alternative splicing of CEACAM1 by hypoxia-inducible factor-1α enhances tolerance to hepatic ischemia in mice and humans", Sci Transl Med, 15, pp.eadf2059~ (2023)
141. Kojima H, "T Cell CEACAM1-TIM-3 crosstalk alleviates liver transplant injury in mice and humans", Gastroenterology, 165, pp.1233~1248 (2023)
142. Terry AQ, "Disulfide-HMGB1 signals through TLR4 and TLR9 to induce inflammatory macrophages capable of innate-adaptive crosstalk in human liver transplantation", Am J Transplant, 23, pp.1858~1871 (2023)
143. Zhang L, "Effect of intraoperative dexmedetomidine on hepatic ischemia-reperfusion injury in pediatric living-related liver transplantation : A propensity score matching analysis", Front Surg, 9, pp.939223~ (2022)
144. Zhang L, "Intraoperative lowdose dexmedetomidine administration associated with reduced hepatic ischemia-reperfusion injury in pediatric deceased liver transplantation : A retrospective cohort study", Ann Transplant, 26, pp.e933354~ (2021)
145. Feng J, "Downregulation of Bmal1 expression in celiac ganglia protects against hepatic ischemia-reperfusion injury", Biomolecules, 13, pp.713~ (2023)
146. Liu L, "Melatonin ameliorates cerebral ischemia-reperfusion injury in diabetic mice by enhancing autophagy via the SIRT1-BMAL1 pathway", FASEB J, 35, pp.e22040~ (2021)
147. Yu S, "m6A-mediated gluconeogenic enzyme PCK1 upregulation protects against hepatic ischemia-reperfusion injury", Hepatology (2023)[DOI]
148. Dong J, "SRY is a key mediator of sexual dimorphism in hepatic ischemia", reperfusion injury, 2022, pp.276, 345~356
149. Czigany Z, "Ischemia-reperfusion injury in marginal liver grafts and the role of hypothermic machine perfusion : molecular mechanisms and clinical implications", J Clin Med, 9, pp.846~ (2020)
150. Palladini G, "Obeticholic acid reduces kidney matrix metalloproteinase activation following partial hepatic ischemia", reperfusion injury in rats, 2022, pp.15, 524~
151. Li S, "Dietary inorganic nitrate protects hepatic ischemia-reperfusion injury through NRF2-mediated antioxidative stress", Front Pharmacol, 12, pp.634115~ (2021)
152. Hou W, "The protective effect of panax notoginseng mixture on hepatic ischemia", reperfusion injury in mice via regulating NR3C2, SRC, and GAPDH, 2021, pp.12, 756259~
153. Wang X, "Susceptibility of rat steatotic liver to ischemiareperfusion is treatable with liver-selective matrix metalloproteinase inhibition", Hepatology, 72, pp.1771~1785 (2020)
154. Zhang P, "Endothelial Notch activation promotes neutrophil transmigration via downregulating endomucin to aggravate hepatic ischemia", reperfusion injury, 2020, pp.63, 375~387
155. Hirao H, "Neutrophil CEACAM1 determines susceptibility to NETosis by regulating the S1PR2", S1PR3 axis in liver transplantation, 2023, pp.133, e162940~

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