본문 바로가기
KERD
논문KCI 등재

Global incidence and prevalence of nonalcoholic fatty liver disease

3

조회

0

다운로드

7

인용

0

참고문헌

키워드

초록

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease worldwide. The estimated global incidence of NAFLD is 47 cases per 1,000 population and is higher among males than females. The estimated global prevalence of NAFLD among adults is 32% and is higher among males (40%) compared to females (26%). The global prevalence of NAFLD has increased over time, from 26% in studies from 2005 or earlier to 38% in studies from 2016 or beyond. The prevalence of NAFLD varies substantially by world region, contributed by differing rates of obesity, and genetic and socioeconomic factors. The prevalence of NAFLD exceeds 40% in the Americas and South-East Asia. The prevalence of NAFLD is projected to increase significantly in multiple world regions by 2030 if current trends are left unchecked. In this review, we discuss trends in the global incidence and prevalence of NAFLD and discuss future projections.

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease worldwide. The estimated global incidence of NAFLD is 47 cases per 1,000 population and is higher among males than females. The estimated global prevalence of NAFLD among adults is 32% and is higher among males (40%) compared to females (26%). The global prevalence of NAFLD has increased over time, from 26% in studies from 2005 or earlier to 38% in studies from 2016 or beyond. The prevalence of NAFLD varies substantially by world region, contributed by differing rates of obesity, and genetic and socioeconomic factors. The prevalence of NAFLD exceeds 40% in the Americas and South-East Asia. The prevalence of NAFLD is projected to increase significantly in multiple world regions by 2030 if current trends are left unchecked. In this review, we discuss trends in the global incidence and prevalence of NAFLD and discuss future projections.

참고문헌 (65)

  1. Cheemerla S, "Global epidemiology of chronic liver disease", Clin Liver Dis(Hoboken), 17, pp.365~370 (2021)
  2. Chalasani N, "The diagnosis and management of nonalcoholic fatty liver disease : practice guidance from the American Association for the Study of Liver Diseases", Hepatology, 67, pp.328~357 (2018)
  3. Riazi K, "The prevalence and incidence of NAFLD worldwide : a systematic review and meta-analysis", Lancet Gastroenterol Hepatol, 7, pp.851~861 (2022)
  4. GBD 2015 Obesity Collaborators, "Health effects of overweight and obesity in 195 countries over 25 years", N Engl J Med, 377, pp.13~27 (2017)
  5. Stefan N, "A global view of the interplay between nonalcoholic fatty liver disease and diabetes", Lancet Diabetes Endocrinol, 10, pp.284~296 (2022)
  6. Tan DJH, "Global burden of liver cancer in males and females : changing etiological basis and the growing contribution of NASH", Hepatology (2022)[DOI]
  7. Huang DQ, "Changing global epidemiology of liver cancer from 2010 to 2019 : NASH is the fastest growing cause of liver cancer", Cell Metab, 34, pp.969~977 (2022)
  8. Younossi ZM, "Nonalcoholic steatohepatitis is the most rapidly increasing indication for liver transplantation in the United States", Clin Gastroenterol Hepatol, 19, pp.580~589 (2021)
  9. Younossi ZM, "Global epidemiology of nonalcoholic fatty liver disease-metaanalytic assessment of prevalence, incidence, and outcomes", Hepatology, 64, pp.73~84 (2016)
  10. Li J, "Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999-2019 : a systematic review and meta-analysis", Lancet Gastroenterol Hepatol, 4, pp.389~398 (2019)
  11. 강성희, "KASL clinical practice guidelines: Management of nonalcoholic fatty liver disease", Clinical and Molecular Hepatology, 27(3), pp.363~401 (2021), 대한간학회
  12. Le MH, "2019 Global NAFLD prevalence : a systematic review and meta-analysis", Clin Gastroenterol Hepatol, 20, pp.2809~2817 (2022)
  13. Wu Y, "The epidemiology of NAFLD in Mainland China with analysis by adjusted gross regional domestic product : a meta-analysis", Hepatol Int, 14, pp.259~269 (2020)
  14. Zhou F, "Unexpected rapid increase in the burden of NAFLD in China from 2008 to 2018 : a systematic review and meta-analysis", Hepatology, 70, pp.1119~1133 (2019)
  15. Im HJ, "Systematic review on the prevalence of nonalcoholic fatty liver disease in South Korea", Clin Res Hepatol Gastroenterol, 45, pp.101526~ (2021)
  16. Jaejun Lee, "Prevalence trends of non-alcoholic fatty liver disease among young men in Korea: A Korean military population- based cross-sectional study", Clinical and Molecular Hepatology, 28(2), pp.196~206 (2022), 대한간학회[DOI]
  17. Seung Ha Park, "Trends in the prevalence of chronic liver disease in the Korean adult population, 1998–2017", Clinical and Molecular Hepatology, 26(2), pp.209~215 (2020), 대한간학회[DOI]
  18. Ito T, "The epidemiology of NAFLD and lean NAFLD in Japan : a metaanalysis with individual and forecasting analysis, 1995-2040", Hepatol Int, 15, pp.366~379 (2021)
  19. "Obesity update 2017"[URL]
  20. "IDF Diabetes Atlas Ninth edition 2019"[URL]
  21. Ikeda N, "What has made the population of Japan healthy?", Lancet, 378, pp.1094~1105 (2011)
  22. "Global Burden of Disease Study 2019 (GBD 2019) results"[URL]
  23. Jeong-Ju Yoo, "Recent research trends and updates on nonalcoholic fatty liver disease", Clinical and Molecular Hepatology, 25(1), pp.1~11 (2019), 대한간학회
  24. Fan JG, "New trends on obesity and NAFLD in Asia", J Hepatol, 67, pp.862~873 (2017)
  25. Nazare JA, "Ethnic influences on the relations between abdominal subcutaneous and visceral adiposity, liver fat, and cardiometabolic risk profile : the International Study of Prediction of Intra-Abdominal Adiposity and Its Relationship With Cardiometabolic Risk", IntraAbdominal Adiposity, 2012, pp.96, 714~726
  26. Hanlon CL, "Nonalcoholic fatty liver disease: the role of visceral adipose tissue", Clin Liver Dis(Hoboken), 19, pp.106~110 (2022)
  27. Yoon KH, "Epidemic obesity and type 2 diabetes in Asia", Lancet, 368, pp.1681~1688 (2006)
  28. Huxley R, "Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertension", Obes Rev, 9(Suppl 1), pp.53~61 (2008)
  29. Chan JC, "Diabetes in Asia : epidemiology, risk factors, and pathophysiology", JAMA, 301, pp.2129~2140 (2009)
  30. Hagström H, "Risk for development of severe liver disease in lean patients with nonalcoholic fatty liver disease : a long-term followup study", Hepatol Commun, 2, pp.48~57 (2018)
  31. Cholongitas E, "Epidemiology of nonalcoholic fatty liver disease in Europe : a systematic review and meta-analysis", Ann Gastroenterol, 34, pp.404~414 (2021)
  32. Nabi O, "Prevalence and risk factors of nonalcoholic fatty liver disease and advanced fibrosis in general population : the French Nationwide NASH-CO Study", Gastroenterology, 159, pp.791~793 (2020)
  33. Bikbov MM, "Prevalence of non-alcoholic fatty liver disease in the Russian Ural Eye and Medical Study and the Ural Very Old Study", Sci Rep, 12, pp.7842~ (2022)
  34. Browning JD, "Prevalence of hepatic steatosis in an urban population in the United States : impact of ethnicity", Hepatology, 40, pp.1387~1395 (2004)
  35. Lazo M, "Prevalence of nonalcoholic fatty liver disease in the United States : the Third National Health and Nutrition Examination Survey, 1988-1994", Am J Epidemiol, 178, pp.38~45 (2013)
  36. Kim D, "Race", ethnicity-based temporal changes in prevalence of NAFLD-related advanced fibrosis in the United States, 2005-2016, 2019, pp.13, 205~213
  37. Zhang X, "Prevalence and factors associated with NAFLD detected by vibration controlled transient elastography among US adults : results from NHANES 2017-2018", PLoS One, 16, pp.e0252164~ (2021)
  38. Sherif ZA, "Global epidemiology of nonalcoholic fatty liver disease and perspectives on US minority populations", Dig Dis Sci, 61, pp.1214~1225 (2016)
  39. Arshad T, "Epidemiology of nonalcoholic fatty liver disease in North America", Curr Pharm Des, 26, pp.993~997 (2020)
  40. Romeo S, "Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease", Nat Genet, 40, pp.1461~1465 (2008)
  41. Wagenknecht LE, "Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort : the Insulin Resistance Atherosclerosis Family Study", Liver Int, 31, pp.412~416 (2011)
  42. Guerrero R, "Ethnic differences in hepatic steatosis : an insulin resistance paradox?", Hepatology, 49, pp.791~801 (2009)
  43. Rojas YAO, "Nonalcoholic fatty liver disease prevalence in Latin America : a systematic review and meta-analysis", Ann Hepatol, 27, pp.100706~ (2022)
  44. Pinto Marques Souza de Oliveira C, "Nonalcoholic fatty liver disease risk factors in Latin American populations: current scenario and perspectives", Clin Liver Dis(Hoboken), 13, pp.39~42 (2019)
  45. Arrese M, "High prevalence of PNPLA3 rs738409(I148M)polymorphism in Chilean latino population and its association to nonalcoholic fatty liver disease risk and histological disease severity", Hepatology, 62(Suppl 1), pp.1285A~ (2015)
  46. Pontoriero AC, "Influence of ethnicity on the distribution of genetic polymorphisms associated with risk of chronic liver disease in South American populations", BMC Genet, 16, pp.93~ (2015)
  47. Chinchilla-López P, "More evidence for the genetic susceptibility of Mexican population to nonalcoholic fatty liver disease through PNPLA3", Ann Hepatol, 17, pp.250~255 (2018)
  48. Patel SA, "Obesity and its relation with diabetes and hypertension : a cross-sectional study across 4 geographical regions", Glob Heart, 11, pp.71~79 (2016)
  49. Gallardo-Rincón H, "Review : type 2 diabetes in Latin America and the Caribbean : regional and country comparison on prevalence, trends, costs and expanded prevention", Prim Care Diabetes, 15, pp.352~359 (2021)
  50. Guthold R, "Worldwide trends in insufficient physical activity from 2001 to 2016: a pooled analysis of 358 population-based surveys with 1·9 million participants", Lancet Glob Health, 6, pp.e1077~e1086 (2018)
  51. Younossi Z, "Global burden of NAFLD and NASH : trends, predictions, risk factors and prevention", Nat Rev Gastroenterol Hepatol, 15, pp.11~20 (2018)
  52. Spearman CW, "Epidemiology, risk factors, social determinants of health, and current management for non-alcoholic fatty liver disease in sub-Saharan Africa", Lancet Gastroenterol Hepatol, 6, pp.1036~1046 (2021)
  53. Ge X, "Prevalence trends in nonalcoholic fatty liver disease at the global, regional and national levels, 1990-2017 : a population-based observational study", BMJ Open, 10, pp.e036663~ (2020)
  54. Roberts SK, "Prevalence of non-alcoholic fatty liver disease in regional Victoria : a prospective population-based study", Med J Aust, 215, pp.77~82 (2021)
  55. Farrell AM, "A problem of proportions : estimates of metabolic associated fatty liver disease and liver fibrosis in Australian adults in the nationwide 2012 AusDiab Study", Sci Rep, 12, pp.1956~ (2022)
  56. Mahady SE, "Burden of non-alcoholic fatty liver disease in Australia", J Gastroenterol Hepatol, 33(Suppl 1), pp.1~11 (2018)
  57. Michael H. Le, "Forecasted 2040 global prevalence of nonalcoholic fatty liver disease using hierarchical bayesian approach", Clinical and Molecular Hepatology, 28(4), pp.841~850 (2022), 대한간학회
  58. Estes C, "Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016-2030", J Hepatol, 69, pp.896~904 (2018)
  59. Estes C, "Modelling NAFLD disease burden in four Asian regions-2019-2030", Aliment Pharmacol Ther, 51, pp.801~811 (2020)
  60. Alswat K, "Nonalcoholic fatty liver disease burden-Saudi Arabia and United Arab Emirates, 2017-2030", Saudi J Gastroenterol, 24, pp.211~219 (2018)
  61. Estes C, "Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease", Hepatology, 67, pp.123~133 (2018)
  62. Swain MG, "Burden of nonalcoholic fatty liver disease in Canada, 2019-2030 : a modelling study", CMAJ Open, 8, pp.E429~E436 (2020)
  63. Adams LA, "Nonalcoholic fatty liver disease burden : Australia, 2019-2030", J Gastroenterol Hepatol, 35, pp.1628~1635 (2020)
  64. Lazarus JV, "Advancing the global public health agenda for NAFLD : a consensus statement", Nat Rev Gastroenterol Hepatol, 19, pp.60~78 (2022)
  65. Karlsen TH, "The EASL-Lancet Liver Commission : protecting the next generation of Europeans against liver disease complications and premature mortality", Lancet, 399, pp.61~116 (2022)

관련 논문AI추천

이 간행물의 다른 논문 (53건)