난소과자극증후군의 치료에 관한 한의 임상 연구 고찰
Review for Clinical Studies of Oriental Medicine on the Treatment of Ovarian Hyperstimulation Syndrome
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Objectives: This review plans to assess the efficacy and effectiveness of oriental medicine for the treatment of Ovarian Hyperstimulation Syndrome (OHSS) through literature research and overview. Methods: Database searching was conducted to identify relevant randomized controlled trials (RCTs) on oriental medicine for the treatment of Ovarian Hyperstimulation Syndrome. Studies were searched from Journal of Korean Obstetrics and Gynecology, Korean Medical Database, Korean studies Information Service System, China National Knowledge Infrastructure, Cochrane library, PubMed and EmBase up to 21st May, 2020. Results: Seventeen studies were finally selected. Fifteen studies intervened with oral Chinese herb medicine, two studies intervened with acupuncture and moxibustion. Nine studies concluded that intervention with oriental medicine significantly relieved OHSS symptoms. Three studies reporting ovary diameter, four studies reporting abdominal circumference and other four studies reporting pelvic effusion showed significant reduction compared to control groups. Six studies showed significantly shorter duration for hospitalization in intervention groups. Only one study showed significantly higher pregnancy rate. Factors related with vascular permeability and blood cell coagulation were significantly lowered in intervention groups in general. Conclusions: From seventeen studies, oriental medicine relieved OHSS symptoms and showed treatment effectiveness. Further strictly designed studies and long-term observed studies are needed to establish evidences.
Abstract
Objectives: This review plans to assess the efficacy and effectiveness of oriental medicine for the treatment of Ovarian Hyperstimulation Syndrome (OHSS) through literature research and overview. Methods: Database searching was conducted to identify relevant randomized controlled trials (RCTs) on oriental medicine for the treatment of Ovarian Hyperstimulation Syndrome. Studies were searched from Journal of Korean Obstetrics and Gynecology, Korean Medical Database, Korean studies Information Service System, China National Knowledge Infrastructure, Cochrane library, PubMed and EmBase up to 21st May, 2020. Results: Seventeen studies were finally selected. Fifteen studies intervened with oral Chinese herb medicine, two studies intervened with acupuncture and moxibustion. Nine studies concluded that intervention with oriental medicine significantly relieved OHSS symptoms. Three studies reporting ovary diameter, four studies reporting abdominal circumference and other four studies reporting pelvic effusion showed significant reduction compared to control groups. Six studies showed significantly shorter duration for hospitalization in intervention groups. Only one study showed significantly higher pregnancy rate. Factors related with vascular permeability and blood cell coagulation were significantly lowered in intervention groups in general. Conclusions: From seventeen studies, oriental medicine relieved OHSS symptoms and showed treatment effectiveness. Further strictly designed studies and long-term observed studies are needed to establish evidences.
참고문헌 (31)
- 김혜옥, "난소과자극증후군의 예측과 예방", Clinical and Experimental Reproductive Medicine, 37(4), pp.293~305 (2010), 대한생식의학회
- 김선민, "난소과자극증후군 환자에서 후천적 혈전성향증의 임상적 의의", Obstetrics & Gynecology Science, 51(7), pp.744~749 (2008), 대한산부인과학회
- Jiang YH, "Research and Progress on the Chinese and Western Medicine Treatment of Ovarian Hyperstimulation Syndrome(卵巢过度刺激综合征的中西医研究进展)", World Latest Medicine Information(Electronic Version), 16(8), pp.49~51 (2016)
- 구수정, "난소과자극증후군의 예방에 관한 한의약 임상 연구 고찰", 대한한방부인과학회지, 33(1), pp.1~18 (2020), 대한한방부인과학회[DOI]
- "Statistics by KDC"[URL]
- Wang Y, "Yishen Jianpi Zhushui Ｒecipe in Treatment of Ovarian Hyperstimulation Syndrome(益肾健脾逐 水 方 治 疗 卵 巢 过 度 刺 激 综 合 征)", ACTA Chinese Medicine, 34(257), pp.2221~2226 (2019)
- Wu L, "Clinical study on 23 cases of ovarian hyperstimulation syndrome treated by"瘀"(从"瘀"论治卵巢过度刺激综合征23例临床研究)", Jiangsu J of Traditional Chinese Medicine, 50(12), pp.39~41 (2018)
- Luo P, "Clinical analysis on the Fuling Daoshui Decoction combined with nursing in the treatment of Deficiency of Spleen and Kidney of ovarian hyperstimulation syndrome(茯苓导水汤联合护理治疗卵巢过度刺激综合征脾肾两虚证临床分析)", Chinese Medicine Distance Education of China, 16(8), pp.146~148 (2018)
- Zuo WT, "Clinical Observation on Treatment of 26Cases of Moderate or Severe Ovarian Hyperstimulation Syndrome with Combination of Traditional Chinese Medicine and Western Medicine(中西医结合治疗26例中重度卵巢过度刺激综合征的疗效观察)", Chinese J of Integrated Traditional and Western Medicine, 37(12), pp.1508~1510 (2017)
- Cai YM, "Clinical curative observation of nursing intervention combined with Fulin Daoshui Decoction for treating Spleenkidney Deficiency type ovarian hyperstimulation syndrome(护理干预配合中药茯苓导水汤加减方治疗卵巢过度刺激综合征脾肾两虚证临床效果观察)", J of Sichuan of Traditional Chinese Medicine, 35(2), pp.198~201 (2017)
- Du J, "Clinical study on treatment of ovarian hyperstimulation syndrome with Jianpi Lishui method(健脾利水法治疗卵巢过度刺激综合征临床研究)", Asia-Pacific Traditional Medicine, 12(12), pp.108~109 (2016)
- Chen Y, "Clinical Observation of Jiawei Shoutai Pill in Treating Ovarian Hyperstimulation Syndrome Caused by IVF-ET(加味寿胎丸治疗IVF-ET术后所致卵巢过度刺激综合征的临床观察)", Guiding J of Traditional Chinese Medicine and Pharmacy, 22(9), pp.78~82 (2016)
- Li XH, "Clinical Observation on Treatment of Ovarian Hyperstimulation Syndrome with Traditional Chinese Medicine(中西医结合治疗卵巢过度刺激综合征临床观察)", J of Emergency in Traditional Chinese Medicine, 24(6), pp.1088~1090 (2015)
- Yang F, "Therapeutic effect of integrated traditional Chinese and Western medicine on patients with ovarian hyperstimulation syndrome(中西医结合治疗卵巢过度刺激综合征患者的疗效观察)", Medical J of Chinese People’s Health, 27(12), pp.92~93 (2015)
- Yi WF, "Clinical Observation on 126 Cases of Ovarian Hyperstimulation Syndrome Treated by Syndrome Differentiation(中医辨证治疗卵巢过度刺激综合征126例临床观察)", Xinjiang J of Traditional Chinese Medicine, 31(2), pp.9~11 (2013)
- Zhao R, "Effect of Cuhuangti Granules on Mild and Moderate Ovarian Hyperstimulation Syndrome(促黄体颗粒治疗轻中度卵巢过度刺激综合征疗效观察)", J of Emergency in Traditional Chinese Medicine, 20(8), pp.1213~1215 (2011)
- Liu FY, "Effect of Yishen Lishui Recipes on Vascular Permeability of the Patients with Ovarian Hyper-Stimulation Syndrome(益肾利水方对卵巢过度刺激综合征患者血管通透性的影响)", J of Traditional Chinese Medicine, 48(11), pp.989~991 (2007)
- Sun YZ, "Clinical Observation on Treatment of Ovarian Hyperstimulation Syndrome with Traditional Chinese Medicine(中西医结合治疗卵巢过度刺激综合征临床观察)", J of Practical Traditional Chinese Medicine, 23(10), pp.660~661 (2007)
- Xie Z, "Large amount of pangolin for treatment of 25 cases of ovarian hyperstimulation syndrome(重用穿山甲治疗卵巢过度刺激综合征25例)", Chinese J of Traditional Medical Science and Technology, 8(5), pp.338~ (2001)
- Qi LL, "Preliminary study on treatment of ovarian hyperstimulation syndrome with traditional Chinese medicine(中药治疗卵巢过度刺激综合征的初步探讨)", Chinese J of Integrated Traditional and Western Medicine, 18(4), pp.248~249 (1998)
- Mou ZN, "Clinical Observation on Acupuncture Combined with Umbilical Cord Therapy on Moderate Ovarian Hyperstimulation Syndrome of Spleen and Kidney Yang Deficiency(针刺联合脐疗治疗中度卵巢过度刺激综合征(脾肾阳虚证)的临床研究)", J of Emergency in Traditional Chinese Medicine, 28(6), pp.958~960 (2019)
- Peng F, "Clinical analysis of traditional Chinese medicine combined with acupuncture and moxibustion for treatment of ovarian hyperstimulation syndrome(中药结合针灸治疗卵巢过度刺激综合征的临床效果分析)", J of Practical Gynecologic Endocrinology(Electronic Edition), 5(20), pp.49~50 (2018)
- Sood A, "Ovarian hyperstimulation syndrome", Obstetrics, Gynaecology and Reproductive Medicine, 5(4), pp.1~5 (2020)
- 석현하, "체외수정시술시 발생한 중증 난소과자극증후군의임상양상 및 위험요인", Obstetrics & Gynecology Science, 51(6), pp.634~641 (2008), 대한산부인과학회
- Al-Shawaf T, "Prevention and treatment of ovarian hyperstimulation syndrome", Best Practice and Research : Clinical Obstetrics and Gynaecology, 17(2), pp.249~261 (2003)
- Golan A, "Symposium :Update on prediction and management of OHSS. A modern classification of OHSS", Reproductive BioMedicine Online, 19(1), pp.28~32 (2009)
- Zivi E, "Ovarian Hyperstimulation Syndrome : Definition, Incidence, and Classification", Seminars in Reproductive Medicine, 28(6), pp.441~447 (2010)
- Banker M, "Revisiting ovarian hyper stimulation syndrome : Towards OHSS free clinic", Journal of Human Reproductive Sciences, 8(1), pp.13~17 (2015)
- Yuan Y, "Effect and mechanism of the prevention and treatment of OHSS(Kidney-Deficiency)by Bushen huoxue formula after IVF(IVF取卵后应用补肾活血方防治肾气虚型卵巢过度刺激综合征的临床结局与机制研究)", Information on Traditional Chinese Medicine, 36(2), pp.26~30 (2019)
- Zheng QH, "Thought and method of applying the acupuncture and moxibustion combined with Chinese herbal medicine in treating ovarian hyperstimulation syndrome(针药结合干预卵巢过度刺激综合征的临床诊疗经验)", China J of Traditional Chinese Med and Pharmacy, 33(11), pp.4981~4983 (2018)
- Cao HJ, "Can Chinese herbal medicine improve outcomes of in vitro fertilization? A systematic review and meta-analysis of randomized controlled trials", PLoS One, 8(12), pp.1~12 (2013)