본문 바로가기
KERD
논문KCI 등재후보

Short-term blood pressure variability as a potential therapeutic target for kidney disease

Jhee Jong Hyun|Ko Ye Eun
대한고혈압학회 (The Korean Society of Hypertension)|2023.01|Clinical Hypertension|제29권 |pp. 23-23|DOI 10.1186/s40885-023-00248-3

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

HypertensionBlood pressureAmbulatory blood pressure monitoringChronic renal insufciency

초록

Short-term blood pressure variability (BPV) measured with ambulatory blood pressure (BP) monitoring has been demonstrated to be significant in predicting various clinical outcomes. Short-term BPV is distinguished from longterm BPV based on the time interval in which BP fluctuations are measured. Increased short-term BPV has been linked to detrimental effects on the microvascular structure and contributes to subclinical organ damage in the heart, blood vessels, and kidneys, regardless of the average 24-h BP levels. Short-term BPV can be defined by various measures, including calculated metrics (standard deviation, coefficient of variation, average real variability, weighted standard deviation, variability independent of the mean) or dipping patterns. Nevertheless, the additional role of short-term BPV beyond the predictive value of average 24-h BPs or established risk factors for cardiovascular disease and kidney disease remains unclear. In particular, longitudinal studies that evaluate the association between short-term BPV and kidney function impairment are limited and no conclusive data exist regarding which short-term BPV indicators most accurately reflect the prognosis of kidney disease. The issue of how to treat BPV in clinical practice is another concern that is frequently raised. This paper presents a review of the evidence for the prognostic role of short-term BPV in kidney outcomes. Additionally, this review discusses the remaining concerns about short-term BPV that need to be further investigated as an independent risk modifier.

Abstract

Short-term blood pressure variability (BPV) measured with ambulatory blood pressure (BP) monitoring has been demonstrated to be significant in predicting various clinical outcomes. Short-term BPV is distinguished from longterm BPV based on the time interval in which BP fluctuations are measured. Increased short-term BPV has been linked to detrimental effects on the microvascular structure and contributes to subclinical organ damage in the heart, blood vessels, and kidneys, regardless of the average 24-h BP levels. Short-term BPV can be defined by various measures, including calculated metrics (standard deviation, coefficient of variation, average real variability, weighted standard deviation, variability independent of the mean) or dipping patterns. Nevertheless, the additional role of short-term BPV beyond the predictive value of average 24-h BPs or established risk factors for cardiovascular disease and kidney disease remains unclear. In particular, longitudinal studies that evaluate the association between short-term BPV and kidney function impairment are limited and no conclusive data exist regarding which short-term BPV indicators most accurately reflect the prognosis of kidney disease. The issue of how to treat BPV in clinical practice is another concern that is frequently raised. This paper presents a review of the evidence for the prognostic role of short-term BPV in kidney outcomes. Additionally, this review discusses the remaining concerns about short-term BPV that need to be further investigated as an independent risk modifier.

참고문헌 (108)

  1. Mancia G, "Short-and long-term blood pressure variability : present and future", Hypertension, 60, pp.512~517 (2012)
  2. Panza JA, "Circadian variation in vascular tone and its relation to alpha-sympathetic vasoconstrictor activity", N Engl J Med, 325, pp.986~990 (1991)
  3. Somers VK, "Sympatheticnerve activity during sleep in normal subjects", N Engl J Med, 328, pp.303~307 (1993)
  4. Stern N, "Circadian rhythm of plasma renin activity in older normal and essential hypertensive men : relation with inactive renin, aldosterone, cortisol and REM sleep", J Hypertens, 4, pp.543~550 (1986)
  5. Weitzman ED, "Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects", J Clin Endocrinol Metab, 33, pp.14~22 (1971)
  6. Brandenberger G, "Nocturnal oscillations in plasma renin activity and REM-NREM sleep cycles in humans : a common regulatory mechanism?", Sleep, 11, pp.242~250 (1988)
  7. Kala R, "Diurnal variation of plasma angiotensin II in man", Scand J Clin Lab Invest, 31, pp.363~365 (1973)
  8. Kawasaki T, "Differences and similarities among circadian characteristics of plasma renin activity in healthy young women in Japan and the United States", Am J Med, 68, pp.91~96 (1980)
  9. Chau NP, "Twenty-four-hour ambulatory blood pressure in shift workers", Circulation, 80, pp.341~347 (1989)
  10. Sternberg H, "Altered circadian rhythm of blood pressure in shift workers", J Hum Hypertens, 9, pp.349~353 (1995)
  11. Sundberg S, "Rapid reversal of circadian blood pressure rhythm in shift workers", J Hypertens, 6, pp.393~396 (1988)
  12. Hanratty R, "Relationship between blood pressure and incident chronic kidney disease in hypertensive patients", Clin J Am Soc Nephrol, 6, pp.2605~2611 (2011)
  13. Velasquez MT, "Ambulatory blood pressure in chronic kidney disease : ready for prime time?", Kidney Int Rep, 1, pp.94~104 (2016)
  14. Pogue V, "Disparate estimates of hypertension control from ambulatory and clinic blood pressure measurements in hypertensive kidney disease", Hypertension, 53, pp.20~27 (2009)
  15. Mulè G, "Relationship between short-term blood pressure variability and subclinical renal damage in essential hypertensive patients", J Clin Hypertens(Greenwich), 17, pp.473~480 (2015)
  16. Leoncini G, "Blood pressure variability and multiple organ damage in primary hypertension", J Hum Hypertens, 27, pp.663~670 (2013)
  17. Jhee JH, "Short-term blood pressure variability and incident CKD in patients with hypertension : findings from the Cardiovascular and Metabolic Disease Etiology Research Center-High Risk(CMERC-HI)Study", Am J Kidney Dis, 81, pp.384~393 (2023)
  18. McMullan CJ, "Prospective analysis of the association of ambulatory blood pressure characteristics with incident chronic kidney disease", J Hypertens, 33, pp.1939~1946 (2015)
  19. Cho SMJ, "Association between nocturnal blood pressure dipping and chronic kidney disease among patients with controlled office blood pressure", Am J Hypertens, 34, pp.821~830 (2021)
  20. Borrelli S, "Short-term blood pressure variability in nondialysis chronic kidney disease patients : correlates and prognostic role on the progression of renal disease", J Hypertens, 36, pp.2398~2405 (2018)
  21. Hara A, "Randomised double-blind comparison of placebo and active drugs for effects on risks associated with blood pressure variability in the Systolic Hypertension in Europe trial", PLoS One, 9, pp.e103169~ (2014)
  22. Verdecchia P, "Day-night dip and early-morning surge in blood pressure in hypertension : prognostic implications", Hypertension, 60, pp.34~42 (2012)
  23. Asayama K, "Prognosis in relation to blood pressure variability : con side of the argument", Hypertension, 65, pp.1170~1179 (2015)
  24. Parati G, "Blood pressure variability : assessment, predictive value, and potential as a therapeutic target", Curr Hypertens Rep, 17, pp.537~ (2015)
  25. Parati G, "Spectral analysis of blood pressure and heart rate variability in evaluating cardiovascular regulation : a critical appraisal", Hypertension, 25, pp.1276~1286 (1995)
  26. Mancia G, "Arterial baroreflexes and blood pressure and heart rate variabilities in humans", Hypertension, 8, pp.147~153 (1986)
  27. Conway J, "Neural and humoral mechanisms involved in blood pressure variability", J Hypertens, 2, pp.203~208 (1984)
  28. Parati G, "Blood pressure variability : its measurement and significance in hypertension", Curr Hypertens Rep, 8, pp.199~204 (2006)
  29. Kotsis V, "Arterial stiffness and 24 h ambulatory blood pressure monitoring in young healthy volunteers : the early vascular ageing Aristotle University Thessaloniki Study(EVA-ARIS Study)", Atherosclerosis, 219, pp.194~199 (2011)
  30. Schillaci G, "Relationship between short-term blood pressure variability and large-artery stiffness in human hypertension : findings from 2 large databases", Hypertension, 60, pp.369~377 (2012)
  31. Fukui M, "Home blood pressure variability on one occasion is a novel factor associated with arterial stiffness in patients with type 2 diabetes", Hypertens Res, 36, pp.219~225 (2013)
  32. Mancia G, "Handbook of hypertension, Pathophysiology of hypertension", pp.17~169 (1997), Elsevier Science
  33. di Rienzo M, "Continuous vs intermittent blood pressure measurements in estimating 24-hour average blood pressure", Hypertension, 5, pp.264~269 (1983)
  34. Hansen TW, "Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations", Hypertension, 55, pp.1049~1057 (2010)
  35. Mena L, "A reliable index for the prognostic significance of blood pressure variability", J Hypertens, 23, pp.505~511 (2005)
  36. Bilo G, "A new method for assessing 24-h blood pressure variability after excluding the contribution of nocturnal blood pressure fall", J Hypertens, 25, pp.2058~2066 (2007)
  37. Maria Korogiannou, "Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against chronic kidney disease patients", Kidney Research and Clinical Practice, 41(4), pp.482~491 (2022), 대한신장학회[DOI]
  38. Rothwell PM, "Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension", Lancet, 375, pp.895~905 (2010)
  39. Rothwell PM, "Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension", Lancet, 375, pp.938~948 (2010)
  40. Stolarz-Skrzypek K, "Blood pressure variability in relation to outcome in the International Database of Ambulatory blood pressure in relation to Cardiovascular Outcome", Hypertens Res, 33, pp.757~766 (2010)
  41. Millar-Craig MW, "Circadian variation of bloodpressure", Lancet, 1, pp.795~797 (1978)
  42. Boggia J, "Prognostic accuracy of day versus night ambulatory blood pressure : a cohort study", Lancet, 370, pp.1219~1229 (2007)
  43. 손형은, "Association of ambulatory blood pressure monitoring with renal outcome in patients with chronic kidney disease", Kidney Research and Clinical Practice, 39(1), pp.70~80 (2020), 대한신장학회[DOI]
  44. Kai H, "Molecular mechanism of aggravation of hypertensive organ damages by shortterm blood pressure variability", Curr Hypertens Rev, 10, pp.125~133 (2014)
  45. Aoki Y, "Large blood pressure variability aggravates arteriolosclerosis and cortical sclerotic changes in the kidney in hypertensive rats", Circ J, 78, pp.2284~2291 (2014)
  46. Freitas FF, "Increased blood pressure variability prior to chronic kidney disease exacerbates renal dysfunction in rats", Front Physiol, 7, pp.428~ (2016)
  47. Knudsen ST, "Ambulatory pulse pressure, decreased nocturnal blood pressure reduction and progression of nephropathy in type 2 diabetic patients", Diabetologia, 52, pp.698~704 (2009)
  48. Palmas W, "Nocturnal blood pressure elevation predicts progression of albuminuria in elderly people with type 2 diabetes", J Clin Hypertens(Greenwich), 10, pp.12~20 (2008)
  49. Palmas W, "Telemedicine home blood pressure measurements and progression of albuminuria in elderly people with diabetes", Hypertension, 51, pp.1282~1288 (2008)
  50. Lurbe E, "Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes", N Engl J Med, 347, pp.797~805 (2002)
  51. Cuspidi C, "Cardiovascular target organ damage in essential hypertensives with or without reproducible nocturnal fall in blood pressure", J Hypertens, 22, pp.273~280 (2004)
  52. Cuspidi C, "Reduced nocturnal fall in blood pressure, assessed by two ambulatory blood pressure monitorings and cardiac alterations in early phases of untreated essential hypertension", J Hum Hypertens, 17, pp.245~251 (2003)
  53. Agarwal R, "Correlates of systolic hypertension in patients with chronic kidney disease", Hypertension, 46, pp.514~520 (2005)
  54. Fava C, "Determinants of kidney function in Swedish families : role of heritable factors", J Hypertens, 26, pp.1773~1779 (2008)
  55. Agarwal R, "GFR, proteinuria and circadian blood pressure", Nephrol Dial Transplant, 24, pp.2400~2406 (2009)
  56. Song J, "The difference between nocturnal dipping status and morning blood pressure surge for target organ damage in patients with chronic kidney disease", J Clin Hypertens(Greenwich), 22, pp.2025~2034 (2020)
  57. Tanner RM, "Association between 24-hour blood pressure variability and chronic kidney disease : a cross-sectional analysis of African Americans participating in the Jackson heart study", BMC Nephrol, 16, pp.84~ (2015)
  58. Sarafidis PA, "Blood pressure variability increases with advancing chronic kidney disease stage : a cross-sectional analysis of 16 546 hypertensive patients", J Hypertens, 36, pp.1076~1085 (2018)
  59. 류지원, "The Clinical Association of the Blood Pressure Variability with the Target Organ Damage in Hypertensive Patients with Chronic Kidney Disease", Journal of Korean Medical Science, 29(7), pp.957~964 (2014), 대한의학회
  60. Wei FF, "Association of target organ damage with 24-hour systolic and diastolic blood pressure levels and hypertension subtypes in untreated Chinese", Hypertension, 63, pp.222~228 (2014)
  61. Madden JM, "Shortterm blood pressure variability over 24 h and target organ damage in middle-aged men and women", J Hum Hypertens, 29, pp.719~725 (2015)
  62. Farrag HM, "Relation of short-term blood pressure variability to early renal effects in hypertensive patients with controlled blood pressure", Blood Press Monit, 24, pp.221~224 (2019)
  63. 안혜림, "Non-Dipper Status and Left Ventricular Hypertrophy as Predictors of Incident Chronic Kidney Disease", Journal of Korean Medical Science, 26(9), pp.1185~1190 (2011), 대한의학회
  64. Turak O, "Morning blood pressure surge as a predictor of development of chronic kidney disease", J Clin Hypertens(Greenwich), 18, pp.444~448 (2016)
  65. Agarwal R, "Prognostic value of circadian blood pressure variation in chronic kidney disease", Am J Nephrol, 30, pp.547~553 (2009)
  66. Agarwal R, "Prognostic importance of ambulatory blood pressure recordings in patients with chronic kidney disease", Kidney Int, 69, pp.1175~1180 (2006)
  67. Redon J, "Nocturnal blood pressure and progression to end-stage renal disease or death in nondiabetic chronic kidney disease stages 3 and 4", J Hypertens, 28, pp.602~607 (2010)
  68. Ida T, "Ambulatory blood pressure monitoring-based analysis of long-term outcomes for kidney disease progression", Sci Rep, 9, pp.19296~ (2019)
  69. Wang C, "Prognostic value of reverse dipper blood pressure pattern in chronic kidney disease patients not undergoing dialysis : prospective cohort study", Sci Rep, 6, pp.34932~ (2016)
  70. Rahman M, "Prognostic significance of ambulatory BP monitoring in CKD : a report from the Chronic Renal Insufficiency Cohort(CRIC)Study", J Am Soc Nephrol, 31, pp.2609~2621 (2020)
  71. Borrelli S, "Dipping status, ambulatory blood pressure control, cardiovascular disease, and kidney disease progression : a multicenter cohort study of CKD", Am J Kidney Dis, 81, pp.15~24 (2023)
  72. Davidson MB, "Association of impaired diurnal blood pressure variation with a subsequent decline in glomerular filtration rate", Arch Intern Med, 166, pp.846~852 (2006)
  73. Jhee JH, "Ambulatory blood pressure variability and risk of cardiovascular events, all-cause mortality, and progression of kidney disease", J Hypertens, 38, pp.1712~1721 (2020)
  74. Wang Q, "C‐STRIDE (Chinese Cohort Study of Chronic Kidney Disease). Short-term systolic blood pressure variability and kidney disease progression in patients with chronic kidney disease: results from C-STRIDE", J Am Heart Assoc, 9, pp.e015359~ (2020)
  75. Liu X, "Association of morning blood pressure surge with chronic kidney disease progression in patients with chronic kidney disease and hypertension", J Clin Hypertens(Greenwich), 23, pp.1879~1886 (2021)
  76. Agarwal R, "Circadian blood pressure classification scheme and the health of patients with chronic kidney disease", Am J Nephrol, 30, pp.536~546 (2009)
  77. Fukuda M, "Nocturnal blood pressure is elevated with natriuresis and proteinuria as renal function deteriorates in nephropathy", Kidney Int, 65, pp.621~625 (2004)
  78. Augustyniak RA, "Sympathetic overactivity as a cause of hypertension in chronic renal failure", J Hypertens, 20, pp.3~9 (2002)
  79. Converse RL Jr, "Sympathetic overactivity in patients with chronic renal failure", N Engl J Med, 327, pp.1912~1918 (1992)
  80. Grassi G, "Early sympathetic activation in the initial clinical stages of chronic renal failure", Hypertension, 57, pp.846~851 (2011)
  81. Johansson M, "Reduced baroreflex effectiveness index in hypertensive patients with chronic renal failure", Am J Hypertens, 18, pp.995~1000 (2005)
  82. Klein IH, "Sympathetic nerve activity is inappropriately increased in chronic renal disease", J Am Soc Nephrol, 14, pp.3239~3244 (2003)
  83. Nielsen FS, "Increased sympathetic activity during sleep and nocturnal hypertension in Type 2 diabetic patients with diabetic nephropathy", Diabet Med, 16, pp.555~562 (1999)
  84. Salman IM, "Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease", Hypertension, 63, pp.804~810 (2014)
  85. Schlaich MP, "Sympathetic activation in chronic renal failure", J Am Soc Nephrol, 20, pp.933~939 (2009)
  86. Tomiyama O, "Baroreflex sensitivity in renal failure", Clin Sci(Lond), 58, pp.21~27 (1980)
  87. Isobe S, "Disturbed circadian rhythm of the intrarenal renin-angiotensin system : relevant to nocturnal hypertension and renal damage", Clin Exp Nephrol, 19, pp.231~239 (2015)
  88. Ozkayar N, "Relationship between blood pressure variability and renal activity of the reninangiotensin system", J Hum Hypertens, 30, pp.297~302 (2016)
  89. Jeong JH, "Nocturnal blood pressure is associated with sympathetic nerve activity in patients with chronic kidney disease", Physiol Rep, 8, pp.e14602~ (2020)
  90. Bolton CH, "Endothelial dysfunction in chronic renal failure : roles of lipoprotein oxidation and pro-inflammatory cytokines", Nephrol Dial Transplant, 16, pp.1189~1197 (2001)
  91. Félétou M, "Endothelial dysfunction : a multifaceted disorder(The Wiggers Award Lecture)", Am J Physiol Heart Circ Physiol, 291, pp.H985~H1002 (2006)
  92. Higashi Y, "Circadian variation of blood pressure and endothelial function in patients with essential hypertension : a comparison of dippers and non-dippers", J Am Coll Cardiol, 40, pp.2039~2043 (2002)
  93. Perticone F, "Endothelial dysfunction and subsequent decline in glomerular filtration rate in hypertensive patients", Circulation, 122, pp.379~384 (2010)
  94. Quinaglia T, "Non-dipping pattern relates to endothelial dysfunction in patients with uncontrolled resistant hypertension", J Hum Hypertens, 25, pp.656~664 (2011)
  95. Yamamoto K, "Renal dysfunction impairs circadian variation of endothelial function in patients with essential hypertension", J Am Soc Hypertens, 4, pp.265~271 (2010)
  96. Abramson JL, "Relation of C-reactive protein and tumor necrosis factor-alpha to ambulatory blood pressure variability in healthy adults", Am J Cardiol, 98, pp.649~652 (2006)
  97. Kim KI, "Association between blood pressure variability and inflammatory marker in hypertensive patients", Circ J, 72, pp.293~298 (2008)
  98. Veerabhadrappa P, "Enhanced blood pressure variability in a high cardiovascular risk group of African Americans : FIT4Life Study", J Am Soc Hypertens, 4, pp.187~195 (2010)
  99. Gönenç A, "Oxidative stress in patients with essential hypertension : a comparison of dippers and nondippers", Eur J Intern Med, 24, pp.139~144 (2013)
  100. Maeda K, "Oxidative stress by peripheral blood mononuclear cells is increased in hypertensives with an extreme-dipper pattern and", or morning surge in blood pressure, 2005, pp.28, 755~761
  101. Parati G, "Assessment and management of blood-pressure variability", Nat Rev Cardiol, 10, pp.143~155 (2013)
  102. Mena LJ, "24-Hour blood pressure variability assessed by average real variability : a systematic review and meta-analysis", J Am Heart Assoc, 6, pp.e006895~ (2017)
  103. 백선하, "Optimal systolic blood pressure in noncritically ill patients with acute kidney injury: A retrospective cohort study", Kidney Research and Clinical Practice, 38(3), pp.356~364 (2019), 대한신장학회[DOI]
  104. 차란희, "Physician perceptions of blood pressure control in patients with chronic kidney disease and target blood pressure achievement rate", Kidney Research and Clinical Practice, 36(4), pp.349~357 (2017), 대한신장학회
  105. 이해경, "Association between blood pressure and the risk of chronic kidney disease in treatment-naïve hypertensive patients", Kidney Research and Clinical Practice, 41(1), pp.31~42 (2022), 대한신장학회[DOI]
  106. Minutolo R, "Changing the timing of antihypertensive therapy to reduce nocturnal blood pressure in CKD : an 8-week uncontrolled trial", Am J Kidney Dis, 50, pp.908~917 (2007)
  107. Parati G, "Blood pressure variability : methodological aspects, clinical relevance and practical indications for management : a European Society of Hypertension position paper", J Hypertens, 41, pp.527~544 (2023)
  108. Schutte AE, "Blood pressure and its variability : classic and novel measurement techniques", Nat Rev Cardiol, 19, pp.643~654 (2022)

관련 논문AI추천

Blood Pressure Variability and Its Management in Hypertensive Patients최희정대한가정의학회 · Korean Journal of Family Medicine2012 · 제33권 제6호Optimal blood pressure target and measurement in patients with chronic kidney disease김수완, 김창성, 마성권, 배은희, 최홍상대한내과학회 · The Korean Journal of Internal Medicine2019 · 제34권 제6호Correlation between short-term blood pressure variability parameters with mobil-O-graph pulse wave velocityCamila Blanco Ferreira Jajah, Dalmo Correia, Geisa Ribeiro Borges, Guilherme Marchiori Moreira, Ian Dias de Souza Pierson, João Lucas Carvalho Achkar, Livia Marchiori Vieira, Lucas Alves Berzotti, Luiz Antonio Pertilli Rodrigues Resende, Marco Antonio Vieira Silva, Mateus Marchiori Vieira, Nicole Cristine Rambourg대한고혈압학회 · Clinical Hypertension2022 · 제28권 Blood Pressure Variability and Vascular Dysfunction in Essential HypertensionXian Wu Cheng대한고혈압학회 · Clinical Hypertension2012 · 제18권 제3호Blood pressure control in patients with chronic kidney diseaseJee Young Lee, Seung Hyeok Han대한내과학회 · The Korean Journal of Internal Medicine2021 · 제36권 제4호Association of the magnitude of the difference in blood pressure between office and ambulatory measurements with blood pressure variability in untreated individuals김병규, 김제상, 김지현, 도웅정, 이무용, Hae-Young Kim, Yea Je Lee대한고혈압학회 · Clinical Hypertension2022 · 제28권

이 간행물의 다른 논문 (32건)

Withdrawal of antihypertensaive medication in young to middle-aged adults: a prospective, single-group, intervention study이해영, 이경숙pp. 1-1Role of home blood pressure monitoring in resistant hypertension김혜미, 신진호pp. 2-2Ideal cardiovascular health metrics and the risk of nonalcoholic fatty liver disease in Korean adultsJung Sun Jae, Kim Seung Up, 김현창, 심선영pp. 3-3The association between carbon and nitrogen stable isotope ratios of human hair and hypertensionJong‑Ku Park, 안성복pp. 4-4Fok I and Bsm I gene polymorphism of vitamin D receptor and essential hypertension: a mechanistic linkRajesh Kumar Khare, Priyanka Thapa Manger, Richa Awasthipp. 5-5
원문 보기