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만성 골반 염증성 질환의 계지복령환 및 계지복령환 가감방 투여에 대한 중의학 연구 동향 : 무작위 대조군 임상 연구를 중심으로

Review of Randomized Controlled Trials Research of Gyejibongnyeong-hwan and Gyejibongnyeong-hwan gagam for Chronic Pelvic Inflammatory Disease

박장경|윤영진|이희윤|정연수
대한한방부인과학회 (The Society Of Oriental Obstetrics & Gynecology)|2023.08|대한한방부인과학회지 (The Journal of Oriental Obstetrics ＆ Gynecology)|제36권 제3호|pp. 78-94

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참고문헌

키워드

Korean MedicineHerbal MedicineChronic Pelvic Inflammatory Disease (CPID)Gyejibongnyeong-hwanGuizhi Fuling WanKeishibukuryo-gan
주제분류한의학

초록

Objectives: The purpose of this study is to review the trends of clinical trials of traditional herbal medicine Gyejibongnyeong-hwan for chronic pelvic inflammatory disease in CNKI. Methods: We searched relevant studies using Chinese National Knowledge Infrastructure (CNKI). Data retrieval was carried out by December 20th, 2021. We analyzed characteristics of study subjects, treatment period, composition of prescription, outcome and adverse event of selected studies and the risk of bias was assessed by using Cochrane's risk of bias tool. Results: Among the total 988 studies, 10 studies met the inclusion criteria. All of the studies were randomized controlled studies and written in Chinese. In all studies, Gyejibongnyeong-hwan was effective in improving chronic pelvic inflammatory disease. Conclusions: This study suggests that Gyejibongnyeong-hwan can be effective in treating chronic pelvic inflammatory disease compared to antibiotics treatment. Further large and well-established randomized placebo controlled trials will be needed.

Abstract

Objectives: The purpose of this study is to review the trends of clinical trials of traditional herbal medicine Gyejibongnyeong-hwan for chronic pelvic inflammatory disease in CNKI. Methods: We searched relevant studies using Chinese National Knowledge Infrastructure (CNKI). Data retrieval was carried out by December 20th, 2021. We analyzed characteristics of study subjects, treatment period, composition of prescription, outcome and adverse event of selected studies and the risk of bias was assessed by using Cochrane's risk of bias tool. Results: Among the total 988 studies, 10 studies met the inclusion criteria. All of the studies were randomized controlled studies and written in Chinese. In all studies, Gyejibongnyeong-hwan was effective in improving chronic pelvic inflammatory disease. Conclusions: This study suggests that Gyejibongnyeong-hwan can be effective in treating chronic pelvic inflammatory disease compared to antibiotics treatment. Further large and well-established randomized placebo controlled trials will be needed.

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