대상회 피질, 편도체, 해마체, 도피질의 T2 이완시간: 1.5테슬러와 3.0테슬러 자기공명영상장치의 비교
T2 Relaxation Times of the Cingulate Cortex, Amygdaloid Body, Hippocampal Body, and Insular Cortex: Comparison of 1.5 T and 3.0 T
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
목적 : 1.5T와 3.0T MRI에서 대상회 피질, 편도체, 해마체, 도피질의 T2 이완시간 (T2)을 비교하고자 하였다. 대상 및 방법 : 건강한 12명의 자원자를 대상으로 1.5T와 3.0T에서 해마에 대해 수직으로FLAIR와 CPMG 펄스열 영상을 같은 조건으로 획득하였다. 대상회 피질, 편도체, 해마체, 도피질에서 T2를 측정하였고, 해마와 나머지 부위의 T2 비를 1.5T와 3.0T 사이에서 비교하였다. 결과 : 1.5T에서 측정한 평균 T2는 대상회 피질, 편도체, 해마체, 도피질에서 각각 109.5±3.1, 117.0±7.1, 114.7±2.4, 111.3±2.4, 3.0T에서 측정한 값은 각각 99.7±3.8,100.7±4.3, 97.9±3, 4, 96.2±2.0 이었다. 1.5T와 3.0T 사이의 T2 변화 백분율은 각각-8.9%, -13.5%, -14.6%, -13.5% 이었다. 1.5T와 3.0T 사이에서 해마체에 대한 대상회 피질, 편도체, 도피질의 T2 비는 각각 0.96 과 1.02 (p=0.003), 1.02 과 1.03 (p > 0.05),0.97 과 0.98 (p > 0.05)이었다. 결론 : 3.0T에서 대상회 피질의 T2 감소는 편도체, 도피질, 해마체와 비교해서 상대적으로 적었고, 대상회 피질과 해마체의 T2 이완시간비는 1.5T와 3.0T에서 의미 있는 차이를 보였다.
Abstract
Purpose : To compare T2 relaxation times (T2) in the cingulate cortex, amygdaloid body, hippocampal body, and insular cortex between 1.5T and 3.0T MR imagers. Materials and Methods : Twelve healthy volunteers underwent FLAIR and CPMG imaging perpendicular to the hippocampal body at both 3.0T and 1.5T. T2 was measured in the cingulate cortex, amygdaloid body, hippocampal body, and insular cortex. The T2 relaxation time ratios of the cingulate cortex, insular cortex, and amygdaloid body to the hippocampal body were compared between 1.5T and 3.0T. Results : The mean T2 of the cingulate cortex, amygdaloid body, hippocampal body, and insular cortex at 1.5T were 109.5±3.1, 117.0±7.1, 114.7±2.4, and 111.3±2.4, respectively; 99.7±3.8, 100.7±4.3, 97.9±3.4, and 96.2±2.0, respectively, at 3.0T. Percentage changes of T2 in the cingulate cortex, insular cortex,amygdaloid body, and hippocampal body at 3.0T with respect to those at 1.5T were -8.9%, -13.5%,-14.6%, and -13.5%, respectively. The mean T2 ratios of the cingulate gyrus, insular cortex, and amygdaloid body to the hippocampal body at 1.5T and 3.0T were 0.96 and 1.02 (p=0.003); 1.02 and 1.03(p>0.05); 0.97 and 0.98 (p>0.05), respectively. Conclusion : T2 decrease in the cingulate cortex was less than the amygdaloid body, insular cortex, and hippocampal body at 3.0T. The mean T2 ratio of the cingulate gyrus to the hippocampal body was significantly different between 1.5T and 3.0T.
참고문헌 (14)
- Frayne R, "Magnetic resonance imaging at 3.0 Tesla: challenges and advantages in clinical neurological imaging", Investigative radiology, 38(7), pp.385~402 (2003)
- Trattnig S, "MR contrast agent at high-field MRI (3 Tesla)", Top Magn Reson Imaging, 14(5), pp.365~375 (2003)
- Lu H, "Routine clinical brain MRI sequences for use at 3.0 Tesla", J Magn Reson Imaging, 22(1), pp.13~22 (2005)
- Hirai T, "Limbic lobe of the human brain: evaluation with turbo fluid-attenuated inversion-recovery MR imaging", Radiology, 215(2), pp.470~475 (2000)
- Whittall KP, "In vivo measurement of T2 distributions and water contents in normal human brain", Magn Reson Med, 37(1), pp.34~43 (1997)
- Schwerdtfeger WK, "Structure and fiber connections of the hippocampus. A comparative study", Adv Anat Embryol Cell Biol, 83, pp.1~74 (1984)
- Duvernoy HM, "Cortical blood vessels of the human brain", Brain Res Bull, 7(5), pp.519~579 (1981)
- Vymazal J, "The relation between brain iron and NMR relaxation times: an in vitro study", Magn Reson Med, 35(1), pp.56~61 (1996)
- Michaeli S, "Proton T2 relaxation study of water, N-acetylaspartate, and creatine in human brain using Hahn and Carr-Purcell spin echoes at 4T and 7T", Magn Reson Med, 47(4), pp.629~633 (2002)
- Hirai T, "T2 shortening in the motor cortex: effect of aging and cerebrovascular diseases", Radiology, 199(3), pp.799~803 (1996)
- Georgiades CS, "MR imaging of the human brain at 1.5 T: regional variations in transverse relaxation rates in the cerebral cortex", AJNR Am J Neuroradiol, 22(9), pp.1732~1737 (2001)
- Briellmann RS, "Comparison of hippocampal volumetry at 1.5 tesla and at 3 tesla", Epilepsia, 42(8), pp.1021~1024 (2001)
- Briellmann RS, "Increased anterior temporal lobe T2 times in cases of hippocampal sclerosis: a multi-echo T2 relaxometry study at 3 T", AJNR Am J Neuroradiol, 25(3), pp.389~394 (2004)
- Pell GS, "Voxel-based relaxometry: a new approach for analysis of T2 relaxometry changes in epilepsy", Neuroimage, 21(2), pp.707~713 (2004)