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장기간 한약 복용한 뇌졸중 환자의 간 및 신장 기능 수치 변화에 대한 증례 보고

A Case Report of Liver and Renal Function Changes in Stroke Patients Taking Long-term Herbal Medicine

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초록

Objectives: This case report describes a patient who had suffered a stroke and who was treated for a long period with herbal medicine in combination with a Western medicine. Methods: Changes in liver function and renal function laboratory tests were measured while the patient took herbal medicine during the 1190 days of hospitalization. Results: During the hospitalization period, the liver function test (LFT) levels were elevated two fold, but after taking the herbal medicine, the LFT levels were stabilized and have remained stable since. Conclusions: The high risk of prescribing herbal medicine by an unlicensed person and the possibility of long-term herbal medicine usage for stabilizing liver function test were shown.

Abstract

Objectives: This case report describes a patient who had suffered a stroke and who was treated for a long period with herbal medicine in combination with a Western medicine. Methods: Changes in liver function and renal function laboratory tests were measured while the patient took herbal medicine during the 1190 days of hospitalization. Results: During the hospitalization period, the liver function test (LFT) levels were elevated two fold, but after taking the herbal medicine, the LFT levels were stabilized and have remained stable since. Conclusions: The high risk of prescribing herbal medicine by an unlicensed person and the possibility of long-term herbal medicine usage for stabilizing liver function test were shown.

참고문헌 (25)

  1. Lee WM, "Recognizing drug-induced liver injury: Current problem, possible solution", Toxicol Pathol, 33(1), pp.155~164 (2005)
  2. Cheon UJ, "A Clinical Study of Patients with Acute Liver Injury Caused by Herbal Medication in Gyeongju Area", Clinical and Molecular Hepatology, 8(2), pp.2287~2728 (2002)
  3. Baek JT, "Over the past five years, Causal Trends of adult acute hepatitis in Daejeon area", Korean J Med, 57(2), pp.352~ (1999)
  4. 박봉기, "Comfrey 등으로 발생한 독성 간손상 환자의 한방치료 1례", 대한한방내과학회지, 30(1), pp.249~255 (2009), 대한한방내과학회
  5. Seo JC, "Clinical Experience of 48 Acute Toxic Hepatitis Patients", Korean Journal of Hepatology, 12(1), pp.74~81 (2006)
  6. 장자원, "부자 및 천오를 포함한 한약이 간 손상 수치에 미치는 영향", 대한한방내과학회지, 26(4), pp.828~835 (2005), 대한한방내과학회
  7. Ha JY, "Effects of Sihosamutang on the CCl4-induced Liner Damage in Rats", Korean J Oriental Medical Pathology, 11(2), pp.27~36 (1997)
  8. Kim SK, "Effect of Artemisia Capillaris Fructus on Fas- FasL-induced Apoptosis in Hepatocyte", Journal of Korean oriental internal medicine, 22(3), pp.353~360 (2001)
  9. Lee E, "A Study on The Side Effects and Toxicity of Herbal Medicine", Korean J Orient int med, 21(5), pp.869~872 (2000)
  10. Lee WM, "Recognizing drug-induced liver injury: Current problem, possible solution", Toxicol Pathol, 33(1), pp.155~164 (2005)
  11. Benichou C, "Criteria of drug-induced liver disorders- Report of an International Consensus Meeting", J Hepatol, 11, pp.272~276 (1990)
  12. Chae HB, "Clinical Manifestations and Diagnosis of drug-induced liver injury", Korean Journal of Hepatology, 10(1), pp.7~18 (2004)
  13. Co-work professor of Korean internal medicine, "Internal Medicine-Gan's System", pp.801~807 (2001), Oriental Medicine Research Center
  14. Kim JC, "Comparison of liver function test score by herbal medication duration.", Korean J Orienh int med, (1), pp.37~45 (2005)
  15. Lee SH, "One case of the hepatic injury suggested toxic hepatitis(drug induced hepatitis) in the treatment of oriental medicine for cerebral infarction", Korean J Orient int med, 21(5), pp.869~872 (2000)
  16. 윤여광, "청심연자탕 투여후 발생한 약물 유인성 간손상 치험 1례", 대한한방내과학회지, 25(3), pp.539~544 (2004), 대한한방내과학회
  17. 최홍식, "생간건비탕을 이용한 급성 약인성 간손상 치험 1례", 대한한방내과학회지, 25(4), pp.207~211 (2004), 대한한방내과학회
  18. Hwang DY, "Bangyaghabpyeon", pp.311~ (2002), yeonglimsa
  19. Benichou C, "Criteria of Dur-induced liver disorders. Repor of an international consensus meeting", J Hepatol, 11, pp.272~276 (1990)
  20. Liu C, "Research Advances on Hepatotoxicity of Herbal Medicines in China", Biomed Research International, 2016(1), pp.1~14 (2016)
  21. Gangyenaegwahaggyosil, "Gangyenaegwaha", pp.926~ (2015), Nado
  22. Lee E, "Saenggangeonbi-tang's Effect on Alcoholic Liver Cirrhosis-1 Cas", J Korean Orienatal Med, 21(3), pp.213~219 (2003)
  23. Hwang SJ, "Effects of Saengkankeonbi-tang on prevention of hyperlipidemia and liver damage induced by alcohol", pp.2009
  24. Hartleb M, "Drug-induced liver damage-a three year study of patients from one gastroenterological department", Med Sci Monit, 8(4), pp.292~296 (2002)
  25. Jung-Hyo Cho, "A nationwide study of the incidence rate of herb-induced liver injury in Korea", Archives of Toxicology, 91(12), pp.4009~4015 (2017), Springer Nature[DOI]

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