유방암에 대한 한양방 병용 치료 증례 보고 1례
A Case Study of a Patient with Breast Cancer Treated with a Combination of Traditional Korean Medicine and Chemotherapy
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The prevalence of breast cancer is very high in Korea. Although the patients receive standard treatments, such as surgery, chemotherapy, or radiotherapy, they frequently experience recurrence or metastasis of their tumors. In addition, many patients with breast cancer also suffer from side effect symptoms induced by these standard treatments. Therefore, increasing numbers of patients now want to undergo treatment with traditional Korean medicine (TKM) in addition to conventional treatment. We present a case of 46-year-old female with recurred breast cancer. She first received two kinds of chemotherapy and then underwent surgery. She then also received 4 cycles of adjuvant chemotherapy. At a follow-up examination, she was informed of recurrent lesions on the right anterior chest wall. She started to receive TKM treatments together with a new chemotherapy. After about one month, the size of the recurred tumor in right chest wall had decreased. Her symptoms, such as shoulder pain, chest pain, and nausea induced by conventional therapy, were also improved. We suggest that a combination of TKM and chemotherapy is a promising treatment for breast cancer.
Abstract
The prevalence of breast cancer is very high in Korea. Although the patients receive standard treatments, such as surgery, chemotherapy, or radiotherapy, they frequently experience recurrence or metastasis of their tumors. In addition, many patients with breast cancer also suffer from side effect symptoms induced by these standard treatments. Therefore, increasing numbers of patients now want to undergo treatment with traditional Korean medicine (TKM) in addition to conventional treatment. We present a case of 46-year-old female with recurred breast cancer. She first received two kinds of chemotherapy and then underwent surgery. She then also received 4 cycles of adjuvant chemotherapy. At a follow-up examination, she was informed of recurrent lesions on the right anterior chest wall. She started to receive TKM treatments together with a new chemotherapy. After about one month, the size of the recurred tumor in right chest wall had decreased. Her symptoms, such as shoulder pain, chest pain, and nausea induced by conventional therapy, were also improved. We suggest that a combination of TKM and chemotherapy is a promising treatment for breast cancer.
참고문헌 (25)
- 이강욱, "유방암 치료에 대한 한의 임상 가이드라인 개발을 위한 기초연구", 대한한방부인과학회지, 29(2), pp.47~65 (2016), 대한한방부인과학회[DOI]
- Chen Z, "Furenliangfangdaiquan", pp.71~ (1993), Jungdam
- Siegel R, "Cancer statistics, 2014", CA Cancer J clin, 64(1), pp.9~29 (2014)
- Desantis C, "Breast cancer statistics 2013", CA Cancer J clin, 64(1), pp.52~62 (2014)
- Park B, "Cancer screening status in Korea, 2011: results from the Korean National Cancer Screening Survey", Asian Pac J Cancer Prev, 13(4), pp.1187~1191 (2012)
- den Hollander P, "Targeted Therapy for Breast Cancer Prevention", Front Oncol, 3(250), pp.1~15 (2013)
- 우희두, "한국 유방암 환자에서 TAC 보조항암화학요법의 독성 및 내성에 대한 연구", Journal of Breast Cancer, 14, pp.44~49 (2011), 한국유방암학회
- 서지영, "항암화학요법을 받는 암 환자의 디스트레스와 삶의 질", Asian Oncology Nursing, 15(1), pp.18~27 (2015), 대한종양간호학회
- 김지혜, "재발성 비소세포성 폐암환자의 Afatinib과 삼칠충초정 병용투여 경과관찰 1례", 대한한방내과학회지, 38(1), pp.72~80 (2017), 대한한방내과학회
- Jang AY, "Potentiation of natural killer(NK) cell activity by methanol extract of cultured cambial meristematic cells of wild ginseng and its mechanism", Life Sci, 135, pp.138~146 (2015)
- Wang W, "Natural product ginsenoside 25-OCH3-PPD inhibits breast cancer growth and metastasis through down-regulating MDM2", PLoS One, 7(7), pp.e41586~ (2012)
- Choi WC, "Study on the Safety and Antitumor Activity of Rhus Verniciflua Extract(Nexia)", pp.2006
- Eisenhauer EA, "New response evaluation criteria in solid tumours: Revised RECIST guideline(version 1.1)", Eur J Cancer, 45(2), pp.228~247 (2009)
- "Terminology Criteria for Adverse Events(CTCAE) v.4.0" (2010)[URL]
- Jang HJ, "Molecular mechanism by which Resina Toxicodendrii induces apoptosis and suppresses chemoresistance in MCF-7", DOX cells, Graduate School of Korean Medicine. Kyunghee University, 2017
- Song MS, "The literature review for Resina Toxicodendrii", J Korean Obstet Gynecol, 15(1), pp.60~76 (2002)
- Lee SH, "The literature review for inhibition of tumor metastasis and growth using ‘activate blood and resolve stasis’ method", Journal of Korean Oriental Medical Research Institute, Daejeon University, 7(1), pp.700~ (1998)
- Kaufman SH, "Apoptosis: Pharmacological Implication and Therapeutic Opportunities" (1997), Academic Press
- -Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells, "Exp Mol Pathol", 2017, 370~376
- Jiang K, "Astragaloside IV inhibits breast cancer cell invasion by suppressing Vav3 mediated Rac1", MAPK signaling, 2017, pp.42, 195~202
- 방선휘, "산삼약침 혈맥주입을 시행한 비소세포성폐암 환자 2례", Journal of Pharmacopuncture, 11(2), pp.13~20 (2008), 대한약침학회
- 조병준, "산삼약침의 자가치료능에 대한 제언", Journal of Pharmacopuncture, 14(2), pp.75~80 (2011), 대한약침학회
- 이경근, "삼중음성유방암과 비삼중음성유방암의 임상병리학적 특성의 비교", 대한외과학회지, 79(1), pp.14~19 (2010), 대한외과학회
- 한솔아, "유방암 환자의 항암 치료 부작용 및 한의학적 보완치료 경험에 관한 포커스 그룹 연구", 대한한방부인과학회지, 30(1), pp.85~94 (2017), 대한한방부인과학회[DOI]
- Greenlee H, "Hershman D. Clinical practice guidelines on the use of integrative therapies as supportive care in patients treated for breast cancer", J Natl Cancer Inst Monogr, 50, pp.346~358 (2014)
