노인에서 반복되는 저나트륨혈증이 삼일신기환 투여로 개선된 1례 : 증례보고
A Case of Recurrent Hyponatremia in the Elderly Improved by Samilsingi-hwan: A Case Report
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Objectives: This report aims to present the case of Korean medicine therapies including Samilsingi-hwan on recurrent hyponatremia in the elderly. Method: A laboratory test was conducted on a patient with general weakness, anorexia, and excess salivation. The patient was diagnosed with hyponatremia and so received intravenous fluid treatment. Results: We continued fluid treatment until electrolyte levels of sodium returned to normal, but the levels gradually dropped repeatedly when the fluid treatment was discontinued. After changing the herbal medicine to Samilsingi-hwan, recurrence of hyponatremia was not seen, even after stopping the fluid treatment. Clinical symptoms also improved during 35 days of hospitalization. Conclusion: This case demonstrates that Samilsingi-hwan may be effective in recurrent hyponatremia in the elderly. Further research is needed.
Abstract
Objectives: This report aims to present the case of Korean medicine therapies including Samilsingi-hwan on recurrent hyponatremia in the elderly. Method: A laboratory test was conducted on a patient with general weakness, anorexia, and excess salivation. The patient was diagnosed with hyponatremia and so received intravenous fluid treatment. Results: We continued fluid treatment until electrolyte levels of sodium returned to normal, but the levels gradually dropped repeatedly when the fluid treatment was discontinued. After changing the herbal medicine to Samilsingi-hwan, recurrence of hyponatremia was not seen, even after stopping the fluid treatment. Clinical symptoms also improved during 35 days of hospitalization. Conclusion: This case demonstrates that Samilsingi-hwan may be effective in recurrent hyponatremia in the elderly. Further research is needed.
참고문헌 (18)
- Department of Internal Medicine, Seoul National University College of Medicine, "SNUH Manual of Medicine", Korea Medical Books, 708~716 (2018)
- Verbalis JG, "Diagnosis, evaluation, and treatment of hyponatremia : expert panel recommendations", Am J Med, 126(10), pp.S1~S42 (2013)
- Siregar P, "The risk of hyponatremia in the elderly compared with younger in the hospital inpatient and outpatient", Acta Med Indones, 43(3), pp.158~161 (2011)
- Corona G, "Moderate Hyponatremia Is Associated with Increased Risk of Mortality : Evidence from a Meta-Analysis", PLOS ONE, 8(12), pp.1~11 (2013)
- Hoorn EJ, "Diagnosis and treatment of hyponatremia : compilation of the guidelines", J Am Soc Nephrol, 28(5), pp.1340~1349 (2017)
- Soiza RL, "Electrolyte and salt disturbances in older people : causes, management and implications", Rev Clin Gerontol, 18(2), pp.143~158 (2008)
- Cheong SJ, "The Effect of Polypharmacy on Mortality in Elderly", Korean J Fam Pract, 6(6), pp.643~650 (2016)
- Lee VW, "Medication adherence:Is it a hidden drug-related problem in hidden elderly?", Geriatr Gerontol Int, 13(4), pp.978~985 (2013)
- Chow KM, "Clinical studies of thiazide-induced hyponatremia", J Natl Med Assoc, 96(10), pp.1305~1308 (2004)
- Ushio-Yamana H, "Renin angiotensin antagonists normalize aberrant activation of epithelial sodium channels in sodium-sensitive hypertension", Nephron Exp Nephrol, 122(3-4), pp.95~102 (2012)
- Jacob S, "Hyponatremia associated with selective serotonin-reuptake inhibitors in older adults", Ann Pharmacother, 40(9), pp.1618~1622 (2006)
- Richard AH, "Lippincott's Illustrated Review: Pharmacology", pp.234~236 (2012), Lippincott Williams & Wilkins
- Park SY, "A Case of Hyponatremia Patient Treated with Hyungbangsabak-san", Korean J Intern Med, (fal), pp.290~298 (2013)
- Renneboog B, "Mild chronic hyponatremia is associated with falls, unsteadiness, and attention deficits", Am J Med, 119(1), pp.7.e1~7.e8 (2016)
- Heo J, "Dongeuibogam", pp.830~831 (2012), Beopin Munhwasa
- Shi SH, "Effects of Liuwei Dihuang tang on kidney Caspase-3 expression and activity in aged mice", Chinese Geriatrics Magazine, 33(2), pp.349~350 (2013)
- Qin X, "Inhibitory Effect of Liuwei Dihuang Decoction on Lymphocyte Apoptosis in Immune Organ of Glucocorticoid_induced Kidney_yin_deficiency Animal Model(II)", Journal of Guangzhou University of Traditional Chinese Medicine, 3 (2000)
- Liu JP, "Effect of ethanol-aqueous extract of Liuwe-idihuang broth on the Yin-deficiency models in mice", Northwest Pharmaceutical Journal, 26(4), pp.265~267 (2011)
