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장기간 NSAIDs를 복용한 섬유근육통 환자의 기능성 소화불량 치험 1례

A Case Report on Functional Dyspepsia in a Fibromyalgia Patient with a History of Long-Term Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Use

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초록

Objective: The purpose of this study was to report the effectiveness of Korean medicine in the treatment of functional dyspepsia in a fibromyalgia patient with a history of long-term NSAIDs use. Methods: The patient was diagnosed as a Soeumin, one of the four constitution types in Korean medicine, and treated with herbal medicines such as Seungyangikgibuja-tang and Pyeongjinsunjeom-san. Acupuncture and moxibustion treatment were also performed. The severity of symptoms was assessed using the Numerical Rating Scale (NRS) of epigastric pain, daily oral intake changes, the Korean Gastrointestinal Symptom Rating Scale (KGSRS), the Gastrointestinal Symptom Score (GIS), and the Functional Dyspepsia-Quality of Life (FD-QOL) score. Results: After treatment for 48 days, the severity of epigastric pain decreased from NRS 8 to NRS 0, and daily oral intake was increased. The KGSRS score decreased from 55 to 43, the GIS score was reduced from 18 to 10, and the FD-QOL score also decreased from 69 to 55. Conclusions: This study suggests that Korean medical treatment could be an effective option for treating functional dyspepsia in fibromyalgia patients with a history of long-term NSAIDs use.

Abstract

Objective: The purpose of this study was to report the effectiveness of Korean medicine in the treatment of functional dyspepsia in a fibromyalgia patient with a history of long-term NSAIDs use. Methods: The patient was diagnosed as a Soeumin, one of the four constitution types in Korean medicine, and treated with herbal medicines such as Seungyangikgibuja-tang and Pyeongjinsunjeom-san. Acupuncture and moxibustion treatment were also performed. The severity of symptoms was assessed using the Numerical Rating Scale (NRS) of epigastric pain, daily oral intake changes, the Korean Gastrointestinal Symptom Rating Scale (KGSRS), the Gastrointestinal Symptom Score (GIS), and the Functional Dyspepsia-Quality of Life (FD-QOL) score. Results: After treatment for 48 days, the severity of epigastric pain decreased from NRS 8 to NRS 0, and daily oral intake was increased. The KGSRS score decreased from 55 to 43, the GIS score was reduced from 18 to 10, and the FD-QOL score also decreased from 69 to 55. Conclusions: This study suggests that Korean medical treatment could be an effective option for treating functional dyspepsia in fibromyalgia patients with a history of long-term NSAIDs use.

참고문헌 (20)

  1. 신성재, "Non-steroidal anti-inflammatory drug-induced enteropathy", Intestinal research, 15(4), pp.446~455 (2017), 대한장연구학회
  2. Yap PRY, "Nonsteroidal Anti-inflammatory Drugs(NSAIDs)Induced Dyspepsia", Curr Pharm Des, 49(4), pp.5073~5081 (2015)
  3. Ofman JJ, "Meta-analysis of dyspepsia and nonsteroidal antiinflammatory drugs", Arthritis Rheum, 49(4), pp.508~518 (2003)
  4. Yasuhiro Fujiwara, "Overlap in Patients With Dyspepsia", Functional Dyspepsia, 2014, pp.20(4), 447~457[DOI]
  5. Derry S, "Oral nonsteroidal anti-inflammatory drugs for fibromyalgia in adults (Review)", Cochrane Database Syst Rev, (3), pp.1~45 (2017)
  6. Schatz RA, "Gastrointestinal and Hepatic Disease in Fibromyalgia", Rheum Dis Clin North Am, 44(1), pp.131~142 (2018)
  7. Kwon SS, "Diagnostic Validity of the Korean Gastrointestinal Symptom Rating Scale(KGSRS)in the Assessment of Gastro-Esophageal Reflux Disease", Ewha Med J, 31(2), pp.73~80 (2008)
  8. Adam B, "Validation of the gastrointestinal symptom score for the assessment of symptoms in patients with functional dyspepsia", Aliment. Pharmacol Ther, 22(4), pp.357~363 (2005)
  9. Lee EH, "Development and validation of a Functional Dyspepsia-Related Quality of Life(FD-QOL)scale in South Korea", J Gastroenterol Hepatol, 21(1), pp.268~274 (2006)
  10. Slim M, "An insight into the gastrointestinal component of fibromyalgia : clinical manifestations and potential underlying mechanisms", Rheumatol Int, 35(3), pp.433~444 (2015)
  11. Macfarlane GJ, "EULAR revised recommendations for the management of fibromyalgia", Ann Rheum Dis, 76(2), pp.318~328 (2017)
  12. Straus WL, "Do NSAIDs cause dyspepsia?A meta-analysis evaluating alternative dyspepsia definitions", Am J Gastroenterol, 97(8), pp.1951~1958 (2002)
  13. Hollenz M, "NSAID-associated dyspepsia and ulcers : A prospective cohort study in primary care", Dig Dis, 24(1-2), pp.189~194 (2006)
  14. Ford AC, "Global prevalence of, and risk factors for, uninvestigated dyspepsia : A meta-analysis", Gut, 64(7), pp.1049~1057 (2015)
  15. El-Serag HB, "Association of esophagitis and esophageal strictures with diseases treated with nonsteroidal anti-inflammatory drugs", Am J Gastroenterol, 92(1), pp.52~56 (1997)
  16. Wilhelmsen I, "Somatization, sensitization, and functional dyspepsia", Scand J Psychol, 43(2), pp.177~180 (2002)
  17. Wallace DJ, "Fibromyalgia : The gastrointestinal link", Curr Pain Headache Rep, 8(5), pp.364~368 (2004)
  18. Drossman DA, "Functional gastrointestinal disorders : History, pathophysiology, clinical features, and Rome IV", Gastroenterology, 150(6), pp.1262~1279 (2016)
  19. 주종천, "소음인체질병증 임상진료지침: 망양병", 사상체질의학회지, 26(1), pp.37~44 (2014), 사상체질의학회[DOI]
  20. Chang IK, "Experimental Studies on Efficacy of Pyungjinsujeomsan", J Kyung Hee Univ Med Cent, 3(4), pp.510~522 (1987)

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