Association of Three Polymorphisms in Porcine Ribosomal protein L27a(RPL27A) Gene with Meat-quality Traits
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
We identified molecular markers associated with meat-quality traits in the porcine RPL27A(ribosomal protein L27a) gene. Three single nucleotide polymorphisms(SNPs) were discovered in the porcine RPL27A gene: g.920T>C, g.1013T>C, and g.1046T>C. The g.920 T>C SNP was significantly associated with pH24(P<0.05) and collagen(P<0.05), while the g.1013T>C and g.1046T>C SNPs were significantly associated with moisture(P<0.05). Either the TTT or CCC haplotype was significantly associated with moisture, pH24 and collagen(P<0.05, respectively). The genotypes of RPL27A associated with meat-quality traits were all located in intron 2. The three SNPs of the RPL27A found in this study will provide useful information for genetic characterization or association studies of meat-quality traits in other populations. Additionally, these markers could potentially be applied in pig breeding programs to improve meat-quality traits after validation in other populations.
Abstract
We identified molecular markers associated with meat-quality traits in the porcine RPL27A(ribosomal protein L27a) gene. Three single nucleotide polymorphisms(SNPs) were discovered in the porcine RPL27A gene: g.920T>C, g.1013T>C, and g.1046T>C. The g.920 T>C SNP was significantly associated with pH24(P<0.05) and collagen(P<0.05), while the g.1013T>C and g.1046T>C SNPs were significantly associated with moisture(P<0.05). Either the TTT or CCC haplotype was significantly associated with moisture, pH24 and collagen(P<0.05, respectively). The genotypes of RPL27A associated with meat-quality traits were all located in intron 2. The three SNPs of the RPL27A found in this study will provide useful information for genetic characterization or association studies of meat-quality traits in other populations. Additionally, these markers could potentially be applied in pig breeding programs to improve meat-quality traits after validation in other populations.
참고문헌 (17)
- Arlington, V. A., "Official methods of analysis of the association of analytical chemists", AOAC, ~ (1980)
- Cho, K., "Association of genetic variants for FABP3 gene with back fat thickness and intramuscular fat content in pig", Mol. Biol. Rep, 38, pp.2161~2166 (2011)
- Fan, B., "Identification of genetic markers associated with residual feed intake and meat quality traits in the pig", Meat Sci, 84, pp.645~650 (2010)
- Gerbens, F., "Associations of heart and adipocyte fatty acid-binding protein gene expression with intramuscular fat content in pigs", J Anim. Sci, 79, pp.347~354 (2001)
- Grau, R., "Eine einfache Methode zur Bestimmung der Wasserbindung in Fleisch", Fleischwirtschaft, 4, pp.295~297 (1952)
- Grau, R., "Die Bestimmung der Wasserbindung des Fleisches mittels der Pressmethode", Fleischwirtschaft, 8, pp.733~736 (1956)
- Kusuda, J., "Genomic structure and chromosome location of RPL27A", Rpl27a, the genes encoding human and mouse ribosomal protein L27A, 1999, pp.85, 248~251
- Li, H., "Quantitative trait loci analysis of swine meat quality traits", J Anim. Sci, 88, pp.2904~2912 (2010)
- Markljung, E., "Genomewide identification of quantitative trait loci in a cross between Hampshire and Landrace II: meat quality traits", BMC genet, 9, pp.22~ (2008)
- Ovilo, C., "Association of MC4R gene variants with growth, fatness, carcass composition and meat and fat quality traits in heavy pigs", Meat Sci, 73, pp.42~47 (2006)
- Reardon, W., "Association of polymorphisms in candidate genes with colour, water-holding capacity, and composition traits in bovine M. longissimus and M. semimembranosus", Meat Sci, 86, pp.270~275 (2010)
- Ryu, Y., "Comparison of histochemical characteristics in various pork groups categorized by postmortem metabolic rate and pork quality", J Anim. Sci, 84, pp.894~901 (2006)
- Stephens, M., "A new statistical method for haplotype reconstruction from population data", Am. J. Hum. Genet, 68, pp.978~989 (2001)
- Stephens, M., "Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation", Am. J. Hum. Genet, 76, pp.449~462 (2005)
- Watanabe, N., "Distribution of allele frequencies at TTN g. 231054C> T, RPL27A g. 3109537C> T and AKIRIN2 c.* 188G> A between Japanese Black and four other cattle breeds with differing historical selection for marbling", BMC Res. Notes, 4, pp.10~ (2011)
- Yamada, T., "Association of a single nucleotide polymorphism in ribosomal protein L27a gene with marbling in Japanese Black beef cattle", Anim. Sci. J, 80, pp.631~635 (2009)
- Yang, H., "Association of 3 polymorphisms in porcine troponin I genes (TNNI1 and TNNI2) with meat quality traits", J. appl. genet, 51, pp.51~57 (2010)