양격산화탕 투여와 식이요법을 병행하여 호전된 공복혈당장애 증례 보고
Case Report of Impaired Fasting Glucose Improved with Korean Medicine Treatment and Dietetic Therapy
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Diabetes mellitus, commonly known as diabetes, comprises a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. Diabetes is classified into type 1 diabetes and type 2 diabetes, and the incidence and prevalence of diabetes, mostly type 2, have increased remarkably in recent decades. A diagnosis of type 2 diabetes is greatly influenced by heredity, and it is important to prevent diabetes in people with a family history by improving lifestyle and environmental factors. Controlling overeating, obesity, lack of exercise, and stress is effective to prevent diabetes. The patient in this case report had impaired fasting glucose and mild hyperlipidemia. The patient experienced improvements in these sequelae after the administration of herbal medicine (Yangkyuksanwha-tang) for 12 weeks and the implementation of a plant-based diet. The complete blood count, XXXX, fasting blood sugar, HbA1c, insulin, and C-peptide levels were measured, and the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) and HOMA-β were calculated according to the FBS and fasting insulin levels. Total cholesterol, triglyceride, FBS, and HbA1c levels all decreased after 12 weeks compared with baseline measures. There was no change in the insulin secretory ability; the C-peptide level did not change as a result of β-cell function; and the HOMA-β level reflected an improved insulin secretory ability.
Abstract
Diabetes mellitus, commonly known as diabetes, comprises a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. Diabetes is classified into type 1 diabetes and type 2 diabetes, and the incidence and prevalence of diabetes, mostly type 2, have increased remarkably in recent decades. A diagnosis of type 2 diabetes is greatly influenced by heredity, and it is important to prevent diabetes in people with a family history by improving lifestyle and environmental factors. Controlling overeating, obesity, lack of exercise, and stress is effective to prevent diabetes. The patient in this case report had impaired fasting glucose and mild hyperlipidemia. The patient experienced improvements in these sequelae after the administration of herbal medicine (Yangkyuksanwha-tang) for 12 weeks and the implementation of a plant-based diet. The complete blood count, XXXX, fasting blood sugar, HbA1c, insulin, and C-peptide levels were measured, and the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) and HOMA-β were calculated according to the FBS and fasting insulin levels. Total cholesterol, triglyceride, FBS, and HbA1c levels all decreased after 12 weeks compared with baseline measures. There was no change in the insulin secretory ability; the C-peptide level did not change as a result of β-cell function; and the HOMA-β level reflected an improved insulin secretory ability.
참고문헌 (29)
- 김도형, "당뇨병의 한의학적 치료에 대한 최신 연구 동향 - 2008년부터 2013년까지 국내 학술논문을 중심으로 -", 대한한방내과학회지, 34(3), pp.240~255 (2013), 대한한방내과학회
- World Health Organization, "10 facts about diabetes:diabetic programme", World Health Organization, ~ (2014)
- Munehiro Kitada, "SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential", Diabetes and Metabolism Journal, 37(5), pp.315~325 (2013), 대한당뇨병학회[DOI]
- Yoo JM, "Fasting Blood Glucose Disorder and Impaired Glucose Tolerance", A Monthly Diabetes Magazine, 11, pp.32~33 (2006)
- Type 2 diabetes clinical research center designated by the Ministry of Health and Welfare, "Instructional guidelines for diabetes treatment", pp.1~6 (2008), Gold Planning
- Association of Korean Medicine Professors for Nephro-Endocrine system, "Nephro-Endocrine system", pp.89~ (2011), Gunja
- Lee JM, "Dongeuisusebowon", pp.70~ (1964), Shinil Publishing Co
- McMacken M, "A plant-based diet for the prevention and treatment of type 2 diabetes", Journal of Geriatric Cardiology, 14(5), pp.342~354 (2017)
- Hong YH, "Analysis of domestic nursing research on diabetes", Journal of Basic Nursing, 8(3), pp.416~429 (2001)
- Statistical Office, "Cause of death statistics in 2019", Statistics Korea, ~ (2020)
- Choi CS, "Review :The mechanism of development of insulin resistance in type 2 diabetes mellitus", The Korean Journal of Medicine, 63(6), pp.613~625 (2002)
- 전기홍, "당뇨병 전단계 및 고위험군 관리와 과학적 근거", 대한의사협회지, 54(10), pp.1020~1027 (2011), 대한의사협회
- 김인수, "加味六味地黃湯이 공복혈당장애와 내당능장애를 가진 경증 당뇨병환자의 혈당조절에 미치는 영향 1례", 동의생리병리학회지, 27(5), pp.677~682 (2013), 한의병리학회
- 고희재, "케톤식이로 발생한 체중감소 및 내당능장애에 침치료 효과", Korean Journal of Acupuncture, 36(4), pp.274~280 (2019), 경락경혈학회[DOI]
- Campbell MK, "Biochemistry" (2015), Cengage Learning
- Borén J, "The central role of arterial retention of cho-lesterol-rich apolipoprotein-B- containing lipoproteins in thepathogenesis of atherosclerosis:a triumph of simplicity", Curr OpinLipidol, 27(5), pp.473~483 (2016)
- Turley SD, "Sterol absorption by the small intestine", Curr Opin Lipidol, 14(3), pp.233~240 (2003)
- Lally S, "Messenger RNA levels ofgenes involved in dysregulation of postprandial lipoproteins intype 2 diabetes:the role of Niemann-Pick C1-like 1. ATP-bindingcassette, transporters G5 and G8 and of microsomal triglyceridetransfer protein", Diabetologia, 49(5), pp.1008~1016 (2006)
- 심영제, "저탄수화물 고지방 식이", Journal of Obesity & Metabolic Syndrome, 25(4), pp.188~189 (2016), 대한비만학회
- Lee HJ, "Insulin Resistance and Visceral Fat Obesity in Hyperlipidemia", Korean Circulation J, 29(7), pp.673~679 (1999)
- 최철수, "인슐린저항성의 발생기전", 대한내과학회지, 77(2), pp.171~177 (2009), 대한내과학회
- Kim CH, "Nutritional Management of the Patients with Diabetes", Hanyang Medical Reviews, 31(4), pp.220~227 (2011)
- 정성일, "少陽人 당뇨병환자에 凉膈散火湯을 투여한 증례", 동의생리병리학회지, 16(6), pp.37~1313 (2002), 한의병리학회
- 김의종, "凉膈散火湯이 실험적 당뇨에 미치는 영향", 동의생리병리학회지, 21(2), pp.474~478 (2007), 한의병리학회
- Yates AP, "Age-related increase in haemoglobin A1c and fasting plasma glucose is accompanied by a decrease in beta cell function without change in insulin sensitivity:evidence from a cross-sectional study of hospital personnel", Diabet Med, 19(3), pp.254~258 (2002)
- 나은희, "건강검진자에서 혈중 당화혈색소(HbA1c)치와 대사증후군과의 관계", Laboratory Medicine Online, 1(1), pp.3~9 (2011), 대한진단검사의학회
- 심완섭, "한국인 제2형 당뇨병에서 식후 인슐린 분비능의 의미", Diabetes and Metabolism Journal, 29(4), pp.367~377 (2005), 대한당뇨병학회
- 김지훈, "인슐린 저항성의 측정 및 임상 적용", Endocrinology and Metabolism, 24(2), pp.75~83 (2009), 대한내분비학회
- 최은숙, "한국인 남성에서 Homeostasis Model Assessment 표지자로 측정한 인슐린저항성 및 인슐린분비능과 당뇨병 발생위험도", Diabetes and Metabolism Journal, 32(6), pp.498~505 (2008), 대한당뇨병학회
