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Selection of appropriate biomatrices for studies of chronic stress in animals: a review

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초록

Cortisol and corticosterone, hormones traditionally considered biomarkers of stress, can be measured in fluid biomatrices (e.g., blood, saliva) from live animals to evaluate conditions at sampling time, or in solid biomatrices (e.g., hair, feather) from live or dead animals to obtain information regarding long-term changes. Using these biomarkers to evaluate physiological stress responses in domestic animals may be challenging due to the diverse characteristics of biomatrices for potential measurement. Ideally, a single measurement from the biomatrix should be sufficient for evaluating chronic stress. The availability of appropriate and cost-effective immunoassay methods for detecting the biomarkers should also be considered. This review discusses the strengths and limitations of different biomatrices with regard to ensuring the highest possible reliability for chronic stress evaluation. Overall, solid biomatrices require less frequent sampling than other biomatrices, resulting in greater time- and cost-effectiveness, greater ease of use, and fewer errors. The multiplex immunoassay can be used to analyze interactions and correlations between cortisol and other stress biomarkers in the same biomatrix. In light of the lack of information regarding appropriate biomatrices for measuring chronic stress, this review may help investigators set experimental conditions or design biological research.

Abstract

Cortisol and corticosterone, hormones traditionally considered biomarkers of stress, can be measured in fluid biomatrices (e.g., blood, saliva) from live animals to evaluate conditions at sampling time, or in solid biomatrices (e.g., hair, feather) from live or dead animals to obtain information regarding long-term changes. Using these biomarkers to evaluate physiological stress responses in domestic animals may be challenging due to the diverse characteristics of biomatrices for potential measurement. Ideally, a single measurement from the biomatrix should be sufficient for evaluating chronic stress. The availability of appropriate and cost-effective immunoassay methods for detecting the biomarkers should also be considered. This review discusses the strengths and limitations of different biomatrices with regard to ensuring the highest possible reliability for chronic stress evaluation. Overall, solid biomatrices require less frequent sampling than other biomatrices, resulting in greater time- and cost-effectiveness, greater ease of use, and fewer errors. The multiplex immunoassay can be used to analyze interactions and correlations between cortisol and other stress biomarkers in the same biomatrix. In light of the lack of information regarding appropriate biomatrices for measuring chronic stress, this review may help investigators set experimental conditions or design biological research.

참고문헌 (111)

  1. Hirsch MS, "A comprehensive review of biomarker use in the gynecologic tract including differential diagnoses and diagnostic pitfalls", Adv Anat Pathol, 27, pp.164~192 (2020)[DOI]
  2. Dhama K, "Biomarkers in stress related diseases", disorders : diagnostic, prognostic, and therapeutic values, 2019, pp.6, 91~
  3. Moberg GP, "The biology of animal stress: basic principles and implications for animal welfare", pp.1~21 (2000), CABI
  4. Ewert A, "Levels of nature and stress response", Behav Sci, 8, pp.49~ (2018)[DOI]
  5. Takahashi A, "Aggression, social stress, and the immune system in humans and animal models", Front Behav Neurosci, 12, pp.56~ (2018)[DOI]
  6. Burdett S., "Exploring the relationships between behavioural responses to stress and performance, carcass composition, energy expenditure and macronutrient oxidation in restrict fed female Yorkshire pigs", Ph.D, pp.2019
  7. GHASSEMINEJAD JALIL, "Behavioral and physiological changes during heat stress in Corriedale ewes exposed to water deprivation", 한국축산학회지, 59(7), pp.1~6 (2017), 한국축산학회
  8. Moberg GP, "The biology of animal stress: basic principles and implications for animal welfare" (2000), CABI
  9. Victoria Sanz Fernandez M, "Effects of heat stress on carbohydrate and lipid metabolism in growing pigs", Physiol Rep, 3, pp.e12315~ (2015)[DOI]
  10. Meyer JS, "The international encyclopedia of primatology", pp.597~598 (2017), Wiley Blackwell
  11. Choe SJ, "Psychological stress deteriorates skin barrier function by activating 11β-hydroxysteroid dehydrogenase 1 and the HPA axis", Sci Rep, 8, pp.6334~ (2018)[DOI]
  12. Lin TK, "Association between stress and the HPA axis in the atopic dermatitis", Int J Mol Sci, 18, pp.2131~ (2017)
  13. Oster H, "The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids", Endocr Rev, 38, pp.3~45 (2017)[DOI]
  14. Hayashi H, "Effect of growth and parturition on hair cortisol in Holstein cattle", Anim Sci J, 92, pp.e13518~ (2021)[DOI]
  15. Kovács L, "Salivary cortisol as a non-invasive approach to assess stress in dystocic dairy calves", Sci Rep, 11, pp.6200~ (2021)[DOI]
  16. Pompa G, "Investigation of the origin of prednisolone in cow urine", Steroids, 76, pp.104~110 (2011)[DOI]
  17. Gellrich K, "Cortisol levels in skimmed milk during the first 22 weeks of lactation and response to short-term metabolic stress and lameness in dairy cows", J Anim Sci Biotechnol, 6, pp.31~ (2015)[DOI]
  18. Ebinghaus A, "Fecal cortisol metabolites in dairy cows : a cross-sectional exploration of associations with animal, stockperson, and farm characteristics", Animals, 10, pp.1787~ (2020)[DOI]
  19. Weaver SJ, "Chronic elevation of plasma cortisol causes differential expression of predominating glucocorticoid in plasma, saliva, fecal, and wool matrices in sheep", Domest Anim Endocrinol, 74, pp.106503~ (2021)[DOI]
  20. Asano K, "Effect of climatic factors on urinary cortisol and peripheral blood leukocytes in lambs grazing on a semi-natural grassland in the Hokuriku district of Japan", Anim Sci J, 92, pp.e13536~ (2021)[DOI]
  21. 최인학, "동물 복지 융합형 디지털 콘텐츠 제작을 위한 야외효력시험에서 이유 자돈의 혈중 Cortisol 분석", 한국환경과학회지, 29(5), pp.575~578 (2020), 한국환경과학회[DOI]
  22. Bahnsen I, "The effect of different feeding systems on salivary cortisol levels during gestation in sows on herd level", Animals, 11, pp.1074~ (2021)[DOI]
  23. Byeonghyeon Kim, "Effects of acute heat stress on salivary metabolites in growing pigs: an analysis using nuclear magnetic resonance-based metabolomics profiling", 한국축산학회지, 63(2), pp.319~331 (2021), 한국축산학회[DOI]
  24. Mohan NH, "Relationship between plasma, saliva, urinary and faecal cortisol levels in pigs", Indian J Anim Sci, 90, pp.768~772 (2020)
  25. Allwin B, "Evaluation of endogenous faecal cortisol as a non invasive assessment of stress in free ranging wild pigs(Sus scrofa)", Indian J Vet Anim Sci Res, 44, pp.89~92 (2015)
  26. Mohamed NA, "Physiological and ion changes of Nile tilapia(Oreochromis niloticus)under the effect of salinity stress", Aquac Rep, 19, pp.100567~ (2021)[DOI]
  27. Hudson JM, "Measurement of cortisol in blow samples collected from free-swimming beluga whales(Delphinapterus leucas)", Mar Mamm Sci, 37, pp.888~900 (2021)[DOI]
  28. Ataallahi M, "Effects of environmental changes during different seasons on hair cortisol concentration as a biomarker of chronic stress in Korean native cattle", Int J Agric Biol, 21, pp.1166~1172 (2019)[DOI]
  29. Comin A, "Hair cortisol level as a retrospective marker of hypothalamic-pituitary-adrenal axis activity in horse foals", Vet J, 194, pp.131~132 (2012)[DOI]
  30. Ghassemi Nejad J, "Wool cortisol is a better indicator of stress than blood cortisol in ewes exposed to heat stress and water restriction", Animal, 8, pp.128~132 (2014)[DOI]
  31. "Dietary fiber for gestating sows during heat stress: effects on reproductive performance and stress level" (2021)[URL]
  32. Weirup L, "Scale cortisol is positively correlated to fin injuries in rainbow trout(Oncorhynchus mykiss)reared in commercial flow through systems", Aquaculture, 543, pp.736924~ (2021)[DOI]
  33. Ghassemi Nejad J, "Measuring hair and blood cortisol in sheep and dairy cattle using RIA and ELISA assay : a comparison", Biol Rhythm Res, 51, pp.887~897 (2020)[DOI]
  34. Mormède P, "Exploration of the hypothalamic-pituitary-adrenal function as a tool to evaluate animal welfare", Physiol Behav, 92, pp.317~339 (2007)[DOI]
  35. Dong Gwon Yu, "Effects of stocking density and dietary vitamin C on performance, meat quality, intestinal permeability, and stress indicators in broiler chickens", 한국축산학회지, 63(4), pp.815~826 (2021), 한국축산학회[DOI]
  36. Thaxton JP, "Corticosterone in commercial broilers", J Appl Poult Res, 14, pp.745~749 (2005)[DOI]
  37. Nohara M, "Evaluation of response to restraint stress by salivary corticosterone levels in adult male mice", J Vet Med Sci, 78, pp.775~780 (2016)[DOI]
  38. Weimer SL, "An evaluation of methods for measuring stress in broiler chickens", Poult Sci, 97, pp.3381~3389 (2018)[DOI]
  39. Erickson RL, "Hair corticosterone measurement in mouse models of type 1 and type 2 diabetes mellitus", Physiol Behav, 178, pp.166~171 (2017)[DOI]
  40. Mohammad Ataallahi, "Effects of feather processing methods on quantity of extracted corticosterone in broiler chickens", 한국축산학회지, 62(6), pp.884~892 (2020), 한국축산학회[DOI]
  41. Hosseindoust A, "Muscle antioxidant activity and meat quality are altered by supplementation of astaxanthin in broilers exposed to high temperature", Antioxidants, 9, pp.1032~ (2020)[DOI]
  42. Lennartsson AK, "Prolactin in response to acute psychosocial stress in healthy men and women", Psychoneuroendocrinology, 36, pp.1530~1539 (2011)[DOI]
  43. Gutiérrez J, "Investigating the role of prolactin as a potential biomarker of stress in castrated male domestic dogs", Animals, 9, pp.676~ (2019)[DOI]
  44. Tothova C, "Acute phase proteins and their use in the diagnosis of diseases in ruminants : a review", Vet Med, 59, pp.163~180 (2014)
  45. García-Torres S, "Assessment of stress by serum biomarkers in calves and their relationship to ultimate pH as an indicator of meat quality", Animals, 11, pp.2291~ (2021)[DOI]
  46. Chen Y, "Models and methods to investigate acute stress responses in cattle", Animals, 5, pp.1268~1295 (2015)[DOI]
  47. Fernandez-Novo A, "The effect of stress on reproduction and reproductive technologies in beef cattle—a review", Animals, 10, pp.2096~ (2020)[DOI]
  48. Trevisi E, "Some physiological and biochemical methods for acute and chronic stress evaluationin dairy cows", Ital J Anim Sci, 8, pp.265~286 (2009)[DOI]
  49. Hughes HD, "Natural variations in the stress and acute phase responses of cattle", Innate Immun, 20, pp.888~896 (2014)[DOI]
  50. Phillips R, "Human nail cortisol as a retrospective biomarker of chronic stress : a systematic review", Psychoneuroendocrinology, 123, pp.104903~ (2021)[DOI]
  51. Mendoza SP, "The biology of animal stress: basic principles and implications for animal welfare", pp.227~247 (2000), CABI
  52. Burnard C, "Hair cortisol and its potential value as a physiological measure of stress response in human and non-human animals", Anim Prod Sci, 57, pp.401~414 (2016)[DOI]
  53. Romero LM, "Physiological stress in ecology : lessons from biomedical research", Trends Ecol Evol, 19, pp.249~255 (2004)[DOI]
  54. Dhabhar FS, "Enhancing versus suppressive effects of stress on immune function : implications for immunoprotection and immunopathology", Neuroimmunomodulation, 16, pp.300~317 (2009)[DOI]
  55. Meyer JS, "Minireview : Hair cortisol : a novel biomarker of hypothalamicpituitary-adrenocortical activity", Endocrinology, 153, pp.4120~4127 (2012)[DOI]
  56. Nedić S, "Cortisol concentrations in hair, blood and milk of Holstein and Busha cattle", Slov Vet Res, 54, pp.163~172 (2017)[DOI]
  57. Heimbürge S, "The use of hair cortisol for the assessment of stress in animals", Gen Comp Endocrinol, 270, pp.10~17 (2019)[DOI]
  58. Russell E, "Hair cortisol as a biological marker of chronic stress : current status, future directions and unanswered questions", Psychoneuroendocrinology, 37, pp.589~601 (2012)[DOI]
  59. "Heat stress in dairy animals: causes, consequences and possible solutions" (2008)[URL]
  60. Trajchev M, "Efficiency of installed cooling systems in dairy barns during hot season", J Agric Food Environ Sci, 71, pp.38~45 (2017)
  61. Herbut P, "Environmental parameters to assessing of heat stress in dairy cattle—a review", Int J Biometeorol, 62, pp.2089~2097 (2018)[DOI]
  62. ATAALLAHI MOHAMMAD, "Evaluation of Substitution of Meteorological Data from the Korea Meteorological Administration for Data from a Cattle Farm in Calculation of Temperature-Humidity Index", 한국기후변화학회지, 11(6), pp.669~678 (2020), 한국기후변화학회[DOI]
  63. Geun Woo Park, "Estimating milk production losses by heat stress and its impacts on greenhouse gas emissions in Korean dairy farms", 한국축산학회지, 64(4), pp.770~781 (2022), 한국축산학회
  64. West JW, "Effects of heat-stress on production in dairy cattle", J Dairy Sci, 86, pp.2131~2144 (2003)[DOI]
  65. Smyth N., "Cortisol secretion in saliva and hair: methodological considerations and relationships with state and trait well-being", Ph.D, pp.2013
  66. French D, "Advances in bioanalytical techniques to measure steroid hormones in serum", Bioanalysis, 8, pp.1203~1219 (2016)[DOI]
  67. Palme R, "Monitoring stress hormone metabolites as a useful, non-invasive tool for welfare assessment in farm animals", Anim Welf, 21, pp.331~337 (2012)[DOI]
  68. Inder WJ, "Measurement of salivary cortisol in 2012 – laboratory techniques and clinical indications", Clin Endocrinol, 77, pp.645~651 (2012)[DOI]
  69. SheriffMJ, "Measuring stress in wildlife : techniques for quantifying glucocorticoids", Oecologia, 166, pp.869~887 (2011)[DOI]
  70. Fukasawa M, "Effect of lactation stage, season and parity on milk cortisol concentration in Holstein cows", Livest Sci, 113, pp.280~284 (2008)[DOI]
  71. Gormally BMG, "What are you actually measuring? A review of techniques that integrate the stress response on distinct time-scales", Funct Ecol, 34, pp.2030~2044 (2020)[DOI]
  72. Genther DJ, "Assessing systemic stress in otolaryngology : methodology and feasibility of hair and salivary cortisol testing", J Nat Sci, 1, pp.e152~ (2015)
  73. "Physiology, cortisol" (2021)[URL]
  74. Hansen SH., "Bioanalysis of pharmaceuticals:sample preparation, separation techniques, and mass spectrometry", pp.23~30 (2015), John Wiley & Sons
  75. Fernández-Peralbo MA, "Preparation of urine samples prior to targeted or untargeted metabolomics mass-spectrometry analysis", TrAC Trends Analyt Chem, 41, pp.75~85 (2012)[DOI]
  76. Niu Z, "Recent advances in biological sample preparation methods coupled with chromatography, spectrometry and electrochemistry analysis techniques", TrAC Trends Analyt Chem, 102, pp.123~146 (2018)[DOI]
  77. Herane-Vives A, "Measuring Earwax Cortisol Concentration using a non-stressful sampling method", Heliyon, 6, pp.e05124~ (2020)[DOI]
  78. Palme R, "Measuring fecal steroids : guidelines for practical application", Ann N Y Acad Sci, 1046, pp.75~80 (2005)[DOI]
  79. Shokry E, "Earwax metabolomics : an innovative pilot metabolic profiling study for assessing metabolic changes in ewes during periparturition period", PLOS ONE, 12, pp.e0183538~ (2017)[DOI]
  80. Trumble SJ, "Blue whale earplug reveals lifetime contaminant exposure and hormone profiles", Proc Natl Acad Sci USA, 110, pp.16922~16926 (2013)[DOI]
  81. Zannoni A, "Non-invasive assessment of fecal stress biomarkers in hunting dogs during exercise and at rest", Front Vet Sci, 7, pp.126~ (2020)[DOI]
  82. Davenport MD, "Analysis of endogenous cortisol concentrations in the hair of rhesus macaques", Gen Comp Endocrinol, 147, pp.255~261 (2006)[DOI]
  83. Sauvé B, "Measurement of cortisol in human hair as a biomarker of systemic exposure", Clin Invest Med, 30, pp.E183~91 (2007)[DOI]
  84. Contreras ET, "Evaluation of hair and nail cortisol concentrations and associations with behavioral, physical, and environmental indicators of chronic stress in cats", J Vet Intern Med, 35, pp.2662~2672 (2021)[DOI]
  85. Aerts J, "Scales tell a story on the stress history of fish", PLOS ONE, 10, pp.e0123411~ (2015)[DOI]
  86. Bortolotti GR, "Corticosterone in feathers is a long-term, integrated measure of avian stress physiology", Funct Ecol, 22, pp.494~500 (2008)[DOI]
  87. Meyer J, "Extraction and analysis of cortisol from human and monkey hair", J Vis Exp, 83, pp.e50882~ (2014)[DOI]
  88. Meyer JS, "Assessment of prenatal stress-related cortisol exposure : focus on cortisol accumulation in hair and nails", Dev Psychobiol, 63, pp.409~436 (2021)[DOI]
  89. Cirimele V, "Identification of ten corticosteroids in human hair by liquid chromatography–ionspray mass spectrometry", Forensic Sci Int, 107, pp.381~388 (2000)[DOI]
  90. Koren L, "A novel method using hair for determining hormonal levels in wildlife", Anim Behav, 63, pp.403~406 (2002)[DOI]
  91. Evans MR, "Heritability of corticosterone response and changes in life history traits during selection in the zebra finch", J Evol Biol, 19, pp.343~352 (2006)[DOI]
  92. Azevedo A, "Age, sex and storage time influence hair cortisol levels in a wild mammal population", PLOS ONE, 14, pp.e0221124~ (2019)[DOI]
  93. Fourie NH, "Sources of variation in hair cortisol in wild and captive non-human primates", Zoology, 119, pp.119~125 (2016)[DOI]
  94. Lutz CK, "Hair cortisol in captive corral-housed baboons", Gen Comp Endocrinol, 302, pp.113692~ (2021)[DOI]
  95. Braun U, "Cortisol concentration of regrown hair and hair from a previously unshorn area in dairy cows", Res Vet Sci, 114, pp.412~415 (2017)[DOI]
  96. Baier F, "Evaluation of hair characteristics and animal age on the impact of hair cortisol concentration in feedlot steers", Front Vet Sci, 6, pp.323~ (2019)[DOI]
  97. Bortolotti GR, "Tracking stress : localisation, deposition and stability of corticosterone in feathers", J Exp Biol, 212, pp.1477~1482 (2009)[DOI]
  98. Won S, "Estimation of greenhouse gas emission from Hanwoo(Korean native cattle)manure management systems", Atmosphere, 11, pp.845~ (2020)[DOI]
  99. "Ross Technical Notes - a practical guide to managing feather cover in broiler breeder females" (2014)[URL]
  100. Freeman NE, "Quantifying corticosterone in feathers: validations for an emerging technique", Conserv Physiol, 6, pp.coy051~ (2018)[DOI]
  101. Jenni-Eiermann S, "Corticosterone : effects on feather quality and deposition into feathers", Methods Ecol Evol, 6, pp.237~246 (2015)[DOI]
  102. Carbajal A, "Feather corticosterone evaluated by ELISA in broilers : a potential tool to evaluate broiler welfare", Poult Sci, 93, pp.2884~2886 (2014)[DOI]
  103. Lattin CR, "Elevated corticosterone in feathers correlates with corticosterone-induced decreased feather quality : a validation study", J Avian Biol, 42, pp.247~252 (2011)[DOI]
  104. Fischer S, "Fingernail cortisol–state of research and future directions", Front Neuroendocrinol, 58, pp.100855~ (2020)[DOI]
  105. Binz TM, "Systematic investigations of endogenous cortisol and cortisone in nails by LC-MS", MS and correlation to hair, 2018, pp.410, 4895~4903
  106. Higashi T, "Methods for determination of fingernail steroids by LC", MS, Steroids, pp.2016, 109[DOI]
  107. Carbajal Brossa A., "Cortisol in skin mucus and scales as a measure of fish stress and habitat quality", Ph.D, pp.2018
  108. 박규현, "Methodological validation of measuring Hanwoo hair cortisol concentration using bead beater and surgical scissors", 한국축산학회지, 61(1), pp.41~46 (2019), 한국축산학회[DOI]
  109. Smrutirekha Mallick, "Development and validation of a simple, sensitive enzyme immunoassay for quantification of androstenedione in bull plasma", 한국축산학회지, 57(4), pp.1~5 (2015), 한국축산학회[DOI]
  110. Elshal MF, "Multiplex bead array assays : performance evaluation and comparison of sensitivity to ELISA", Methods, 38, pp.317~323 (2006)[DOI]
  111. Leng SX, "ELISA and multiplex technologies for cytokine measurement in inflammation and aging research", J Gerontol A Biol Sci Med Sci, 63, pp.879~884 (2008)[DOI]

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