한방병원 중증치료실 입원 중 항생제 연관성 설사를 진단받은 환자에 대한 임상적 고찰
Clinical Study of Antibiotic-associated Diarrhea Treatment in Intensive Care Unit Patients at an Oriental Hospital
1
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objectives : This study was designed to investigate the effectiveness of adjunctive herbal therapy combined with conventional therapy on antibiotic-associated diarrhea (AAD) treatment. Methods : The medical records of 25 patients admitted to the Intensive Care Unit at Kyunghee Oriental Medical Center between January 1, 2009 and January 30, 2010 were reviewed. The charts were analyzed for the general characteristics, site of infection, predominant bacteria, antibiotic treatment, herbal medicine treatment, effect on liver and kidney functions, and the effect of therapy on diarrheal duration. Results : 48% of the 25 patients were male while 52% were female. The average age was 67.2 years old. The most commonly used antibiotic was fluoroquinolone (40.0%) and the most commonly used herbal medicine was Samchulkunbi-tang (24.0%). The average diarrheal duration was 8.9 days. No significant change in hepatic and renal function was discovered before and after treatment with herbal medicine. Conclusions : The results suggest that herbal therapy would be a safe and effective treatment for AAD. Further study investigating the usage of herbal medicine in AAD treatment is anticipated.
Abstract
Objectives : This study was designed to investigate the effectiveness of adjunctive herbal therapy combined with conventional therapy on antibiotic-associated diarrhea (AAD) treatment. Methods : The medical records of 25 patients admitted to the Intensive Care Unit at Kyunghee Oriental Medical Center between January 1, 2009 and January 30, 2010 were reviewed. The charts were analyzed for the general characteristics, site of infection, predominant bacteria, antibiotic treatment, herbal medicine treatment, effect on liver and kidney functions, and the effect of therapy on diarrheal duration. Results : 48% of the 25 patients were male while 52% were female. The average age was 67.2 years old. The most commonly used antibiotic was fluoroquinolone (40.0%) and the most commonly used herbal medicine was Samchulkunbi-tang (24.0%). The average diarrheal duration was 8.9 days. No significant change in hepatic and renal function was discovered before and after treatment with herbal medicine. Conclusions : The results suggest that herbal therapy would be a safe and effective treatment for AAD. Further study investigating the usage of herbal medicine in AAD treatment is anticipated.
참고문헌 (27)
- 구자설, "설사", 대한소화기학회지, 49(4), pp.380~391 (2007)
- Gregory A Cote, "Antibiotic -associated diarrhoea", Expert Opin. Drug Saf, 5(3), pp.361~372 (2006)
- 박혜선, "항생제 연관 설사의 치료", 대한소화기학회지, 54(1), pp.5~12 (2009), 대한소화기학회
- A. Reintam, "Gastrointestinal symptoms in intensive care patients", Acta Anaesthesiol scand, 53, pp.318~324 (2009)
- Suzie Ferrie, "Managing diarrhoea in intensive care", Australian Clinical Care, 20, pp.7~13 (2007)
- 김우주, "중환자실에서의 내성 세균과 항생제 요법", 대한 중환자의학회지, 14(1), pp.14~20 (1999)
- Ana paula Marcon, "Nosocomial Diarrhea in the Intensive Care Unit", Braz J Infect Dis, 10(6), pp.384~389 (2006)
- Brian P. Dorman, "Bowel management in the intensive care unit", intensive and Critical Care Nursing, 20, pp.320~329 (2004)
- O'Connor JR, "Clostridium difficile infection caused by the epidemic BI", NAP1, Gastro-enterology, pp.2009, 136[DOI]
- 김홍재, "발열을 주소로 내원한 정상 면역 환자에서 초기 혈액 배양 검사의 유용성", 대한응급의학회지, 17(5), pp.463~470 (2006), 대한응급의학회
- 최혜숙, "다약제 내성 Acinetobacter baumannii에 의한 폐렴에서 Colistin 분무치료의 효과", Tuberculosis and Respiratory Diseases, 64(1), pp.8~14 (2008), 대한결핵및호흡기학회
- Archibald LK, "Secular trends in hospital-acquired Clostridium difficile disease in the United States, 1987-2001", J. Infect. Dis., 189, pp.1585~1589 (2004)
- Tarek Ali Rushdi, "Control of diarrhea by fiber-enriched diet in ICU patients on enteral nutrition: a prospective randomized controlled trial", Clinical nutrition, 23, pp.1344~1352 (2004)
- 최병철, "泄瀉의 病因病機에 관한 文獻的 考察", 대전대학교 한의학연구소 논문집, 16(1), pp.207~213 (2007)
- 안영상, "泄瀉의 舍岩鍼法 活用에 대한 文獻考察", 경락경혈학회지, 23(3), pp.17~27 (2006), 경락경혈학회
- 임중화, "비위관 급식환자에서의 설사 치험 2례", 대한한의학회지, 24(3), pp.622~628 (2003), 대한한의학회
- 한종현, "慢性泄瀉患者에 대한 藿香正氣散 치험2례 보고", 대한한방내과학회지, 26(4), pp.889~896 (2005), 대한한방내과학회
- 金璋顯, "小兒泄瀉에 대한 加減錢氏白朮散의 臨床效能에 관한 硏究", J Korean Oriental Pediatrics, 18(2), pp.1~9 (2004)
- 이미향, "최근 3년간(2003년~2005년) 건양대학교병원 중환자실에서 분리된 각종 병원성 세균의 항균제 내성양상", 건양의대 학술지, 6(1), pp.16~21 (2006)
- 김태균, "蔘朮健脾湯이 胃腸管에 미치는 影響에 關한 實驗的 硏究", 大韓韓方內科學會誌, 18(1), pp.1~14 (1997)
- 장인규, "過敏性 大腸症候群의 臨床的 考察", 대한한의학회지, 6(2), pp.30~33 (1985)
- 유진덕, "東醫寶鑑 中 平胃散連繫方의 活用에 대한 考察", 대한한의학 방제학회지, 12(1), pp.1~27 (2004)
- Lynne V. McFarland, "Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections", Anaerobe, 15, pp.274~280 (2009)
- 홍명호, "급성 설사의 치료 전략", J Korean Acad Farm Med., 22(12), pp.1697~1704 (2001)
- 김갑득, "급성 설사환자에서 대변 배양검사 시행 및 항생제 사용의 결정", 대한응급의학회지, 12(1), pp.64~73 (2001)
- 김슬지, "한방병원 중환자실에 입원한 뇌졸중에 병발된 폐렴환자에 대한 임상적 고찰", 대한한방내과학회 춘계학술대회지, pp.122~131 (2009)
- 한동하, "뇌졸중에 병발된 폐렴 환자 47례에 관한 임상적 고찰", 대한한의학회지, 13(2), pp.44~51 (1992)