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Effect of Phenanthrene on Gill Biotransformation in Olive Flounder (Paralichthys olivaceus)

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주제분류수산학

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Abstract

The potential of phenanthrene to induce xenobiotic responses was investigated. Olive flounder (Paralichthys olivaceus) was exposed to different levels of phenanthrene (0.5, 1 and 2μM) for 4 weeks. Gill CYP450 content and EROD (ethoxyresorufin O-deethylation) activity were found to be significant in the flounders treated with the higher concentration of phenanthrene (>1.0μM), however, there were no significant changes in gill PROD (penthoxyresorufin O-deethylation) activity in all treated groups compared to the controls. This study demonstrated that phenanthrene has potential to induce gill cytochrome P450 and EROD enzyme in olive flounder.

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