불현성 갑상선기능저하증에 대한 이선탕 가미 처방 투여 경과 : 증례보고
Subclinical Hypothyroidism Treated by Means of Modified Er-Xian Decoction
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Objectives: This study is the first report on a case of subclinical hypothyroidism treated with Modified Er-Xian Decoction, which is rarely used in Korea. Methods: Patients were treated for 3 months with Modified Er-Xian Decoction and their therapeutic effects were evaluated through thyroid function tests and Spleen-Kidney deficiency Questionnaire. Results: Initial improvement was apparent after the administration of Modified Er-Xian Decoction. After 3 months of treatment, the patient 's Spleen-Kidney deficiency index improved significantly, and thyroid hormone levels returned to normal. Conclusions: In this case report, symptoms and biochemical improvement were confirmed based on a single herbal medicine prescription for subclinical hypothyroidism. It is necessary to verify the effect of this prescription through well - established clinical trials.
Abstract
Objectives: This study is the first report on a case of subclinical hypothyroidism treated with Modified Er-Xian Decoction, which is rarely used in Korea. Methods: Patients were treated for 3 months with Modified Er-Xian Decoction and their therapeutic effects were evaluated through thyroid function tests and Spleen-Kidney deficiency Questionnaire. Results: Initial improvement was apparent after the administration of Modified Er-Xian Decoction. After 3 months of treatment, the patient 's Spleen-Kidney deficiency index improved significantly, and thyroid hormone levels returned to normal. Conclusions: In this case report, symptoms and biochemical improvement were confirmed based on a single herbal medicine prescription for subclinical hypothyroidism. It is necessary to verify the effect of this prescription through well - established clinical trials.
참고문헌 (29)
- Peeters RP, "Subclinical Hypothyroidism", N Engl J Med, 376(26), pp.2556~2565 (2017)
- Garber JR, "Clinical practice guidelines for hypothyroidism in adults : cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association", Endocr Pract, 18(6), pp.988~1028 (2012)
- Pearce SH, "2013 ETA guideline : management of subclinical hypothyroidism", Eur Thyroid J, 2(4), pp.215~228 (2013)
- Burns RB, "Should We Treat for Subclinical Hypothyroidism? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center", Ann Intern Med, 164(11), pp.764~770 (2016)
- Mancini A, "Thyroid Hormones, Oxidative Stress, and Inflammation", ediators of Inflammation, 2016, pp.6757154~ (2016)
- Zhong LL, "controlled trial of a Chinese herbal formula(Er-Xian decoction)for menopausal symptoms in Hong Kong perimenopausal women", Menopause, 20(7), pp.767~776 (2013)
- Sun XX, "Clinical Research on Hashimoto’s Hypothyroidism Women of childbearing age using Tonifying Kidney and Invigorating Spleen Decoction for the Pre Conditioning", Masters, pp.2017
- Zhen YJ, "Clinical study on Jianpi Yishen Huazhuo therapy for Hashimoto’s thyroiditis with hypothyroidism", Masters, pp.2017
- Kang KH, "A case report of Hashimoto's thyroiditis treated with Anjeonleejoong-tang", J Int Korean Med, 26(111), pp.103~110 (2005)
- 우성호, "불현성 갑상선기능저하증이 병발한 고령의 뇌졸중 환자의 호전 1례", 대한한방내과학회지, 28(3), pp.624~631 (2007), 대한한방내과학회
- 이민혜, "2000년 이후 갑상선 기능저하증에 대한 국내 한의학 실험연구 체계적 고찰", 대한한방내과학회지, 36(4), pp.570~581 (2015), 대한한방내과학회
- Sun XX, "Clinical reserach on Hashimoto's hypothyroidism women of childbearing age using tonifying kidney and invigorating spleen decoction for the pre conditioning", Master's, pp.2017
- Pearce SH, "2013 ETA Guideline : Management of Subclinical Hypothyroidism", Eur Thyroid J, 2(4), pp.215~228 (2013)
- Karachalios GN, "Subacute thyroiditis presenting as fever of unknown origin", Int J Clin Pract, 64(1), pp.97~98 (2010)
- Roos A, "Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects", J Clin Endocrinol Metab, 92(2), pp.491~496 (2007)
- Stanická S, "Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy", Clin Chem Lab Med, 43(7), pp.715~720 (2005)
- Diekman T, "Increased oxidizability of low-density lipoproteins in hypothyroidism", J Clin Endocrinol Metab, 83(5), pp.1752~1755 (1998)
- Klein I, "Thyroid disease and the heart", Circulation, 116(15), pp.1725~1735 (2007)
- Wang C, "A multiple-dimension liquid chromatography coupled with mass spectrometry data strategy for the rapid discovery and identification of unknown compounds from a Chinese herbal formula(Er-xian decoction)", J Chromatogr A, 1518, pp.59~69 (2017)
- Cheung HP, "Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals", Chin Med, 12, pp.1~ (2017)
- Santin AP, "Role of Estrogen in Thyroid Function and Growth Regulation", Journal of Thyroid Research, 2011, pp.875125~ (2011)
- 서부일, "仙茅 熱水 추출물의 Collagen 유발 관절염에 대한 약리 효능 연구", 대한본초학회지, 31(4), pp.1~10 (2016), 대한본초학회
- Sze SC, "Herba Epimedii : anti-oxidative properties and its medical implications", Molecules, 15(11), pp.7861~7870 (2010)
- Nie Y, "Medicinal plants of genus Curculigo : traditional uses and a phytochemical and ethnopharmacological review", J Ethnopharmacol, 147(3), pp.547~563 (2013)
- Ma H, "The genus Epimedium : an ethnopharmacological and phytochemical review", J Ethnopharmacol, 134(3), pp.519~541 (2011)
- Yang L, "Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase(CYP19)", J Ethnopharmacol, 145(3), pp.715~721 (2013)
- Stachenfeld NS, "Sex Hormone Effects on Body Fluid Regulation", Exercise and sport sciences reviews, 36(3), pp.152~159 (2008)
- Iwen KA, "Thyroid Hormones and the Metabolic Syndrome", European Thyroid Journal, 2(2), pp.83~92 (2013)
- Liu C, "Chinese Herbal Medicine on Cardiovascular Diseases and the Mechanisms of Action", Frontiers in Pharmacology, 7, pp.469~ (2016)
