본문 바로가기
KERD
논문KCI 등재

불현성 갑상선기능저하증에 대한 이선탕 가미 처방 투여 경과 : 증례보고

Subclinical Hypothyroidism Treated by Means of Modified Er-Xian Decoction

0

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류한의학

초록

Objectives: This study is the first report on a case of subclinical hypothyroidism treated with Modified Er-Xian Decoction, which is rarely used in Korea. Methods: Patients were treated for 3 months with Modified Er-Xian Decoction and their therapeutic effects were evaluated through thyroid function tests and Spleen-Kidney deficiency Questionnaire. Results: Initial improvement was apparent after the administration of Modified Er-Xian Decoction. After 3 months of treatment, the patient 's Spleen-Kidney deficiency index improved significantly, and thyroid hormone levels returned to normal. Conclusions: In this case report, symptoms and biochemical improvement were confirmed based on a single herbal medicine prescription for subclinical hypothyroidism. It is necessary to verify the effect of this prescription through well - established clinical trials.

Abstract

Objectives: This study is the first report on a case of subclinical hypothyroidism treated with Modified Er-Xian Decoction, which is rarely used in Korea. Methods: Patients were treated for 3 months with Modified Er-Xian Decoction and their therapeutic effects were evaluated through thyroid function tests and Spleen-Kidney deficiency Questionnaire. Results: Initial improvement was apparent after the administration of Modified Er-Xian Decoction. After 3 months of treatment, the patient 's Spleen-Kidney deficiency index improved significantly, and thyroid hormone levels returned to normal. Conclusions: In this case report, symptoms and biochemical improvement were confirmed based on a single herbal medicine prescription for subclinical hypothyroidism. It is necessary to verify the effect of this prescription through well - established clinical trials.

참고문헌 (29)

  1. Peeters RP, "Subclinical Hypothyroidism", N Engl J Med, 376(26), pp.2556~2565 (2017)
  2. Garber JR, "Clinical practice guidelines for hypothyroidism in adults : cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association", Endocr Pract, 18(6), pp.988~1028 (2012)
  3. Pearce SH, "2013 ETA guideline : management of subclinical hypothyroidism", Eur Thyroid J, 2(4), pp.215~228 (2013)
  4. Burns RB, "Should We Treat for Subclinical Hypothyroidism? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center", Ann Intern Med, 164(11), pp.764~770 (2016)
  5. Mancini A, "Thyroid Hormones, Oxidative Stress, and Inflammation", ediators of Inflammation, 2016, pp.6757154~ (2016)
  6. Zhong LL, "controlled trial of a Chinese herbal formula(Er-Xian decoction)for menopausal symptoms in Hong Kong perimenopausal women", Menopause, 20(7), pp.767~776 (2013)
  7. Sun XX, "Clinical Research on Hashimoto’s Hypothyroidism Women of childbearing age using Tonifying Kidney and Invigorating Spleen Decoction for the Pre Conditioning", Masters, pp.2017
  8. Zhen YJ, "Clinical study on Jianpi Yishen Huazhuo therapy for Hashimoto’s thyroiditis with hypothyroidism", Masters, pp.2017
  9. Kang KH, "A case report of Hashimoto's thyroiditis treated with Anjeonleejoong-tang", J Int Korean Med, 26(111), pp.103~110 (2005)
  10. 우성호, "불현성 갑상선기능저하증이 병발한 고령의 뇌졸중 환자의 호전 1례", 대한한방내과학회지, 28(3), pp.624~631 (2007), 대한한방내과학회
  11. 이민혜, "2000년 이후 갑상선 기능저하증에 대한 국내 한의학 실험연구 체계적 고찰", 대한한방내과학회지, 36(4), pp.570~581 (2015), 대한한방내과학회
  12. Sun XX, "Clinical reserach on Hashimoto's hypothyroidism women of childbearing age using tonifying kidney and invigorating spleen decoction for the pre conditioning", Master's, pp.2017
  13. Pearce SH, "2013 ETA Guideline : Management of Subclinical Hypothyroidism", Eur Thyroid J, 2(4), pp.215~228 (2013)
  14. Karachalios GN, "Subacute thyroiditis presenting as fever of unknown origin", Int J Clin Pract, 64(1), pp.97~98 (2010)
  15. Roos A, "Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects", J Clin Endocrinol Metab, 92(2), pp.491~496 (2007)
  16. Stanická S, "Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy", Clin Chem Lab Med, 43(7), pp.715~720 (2005)
  17. Diekman T, "Increased oxidizability of low-density lipoproteins in hypothyroidism", J Clin Endocrinol Metab, 83(5), pp.1752~1755 (1998)
  18. Klein I, "Thyroid disease and the heart", Circulation, 116(15), pp.1725~1735 (2007)
  19. Wang C, "A multiple-dimension liquid chromatography coupled with mass spectrometry data strategy for the rapid discovery and identification of unknown compounds from a Chinese herbal formula(Er-xian decoction)", J Chromatogr A, 1518, pp.59~69 (2017)
  20. Cheung HP, "Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals", Chin Med, 12, pp.1~ (2017)
  21. Santin AP, "Role of Estrogen in Thyroid Function and Growth Regulation", Journal of Thyroid Research, 2011, pp.875125~ (2011)
  22. 서부일, "仙茅 熱水 추출물의 Collagen 유발 관절염에 대한 약리 효능 연구", 대한본초학회지, 31(4), pp.1~10 (2016), 대한본초학회
  23. Sze SC, "Herba Epimedii : anti-oxidative properties and its medical implications", Molecules, 15(11), pp.7861~7870 (2010)
  24. Nie Y, "Medicinal plants of genus Curculigo : traditional uses and a phytochemical and ethnopharmacological review", J Ethnopharmacol, 147(3), pp.547~563 (2013)
  25. Ma H, "The genus Epimedium : an ethnopharmacological and phytochemical review", J Ethnopharmacol, 134(3), pp.519~541 (2011)
  26. Yang L, "Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase(CYP19)", J Ethnopharmacol, 145(3), pp.715~721 (2013)
  27. Stachenfeld NS, "Sex Hormone Effects on Body Fluid Regulation", Exercise and sport sciences reviews, 36(3), pp.152~159 (2008)
  28. Iwen KA, "Thyroid Hormones and the Metabolic Syndrome", European Thyroid Journal, 2(2), pp.83~92 (2013)
  29. Liu C, "Chinese Herbal Medicine on Cardiovascular Diseases and the Mechanisms of Action", Frontiers in Pharmacology, 7, pp.469~ (2016)

관련 논문AI추천

이 간행물의 다른 논문 (18건)