항암화학요법과 한방치료를 병행하여 전환수술이 가능하게 호전된 진행성 위암 환자 1례
A Case Report of an Advanced Gastric Cancer Patient Who Was Able to Undergo Conversion Surgery Treated with Chemotherapy and Korean Medicine
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Objectives: The purpose of this study was to report a case of a patient with advanced gastric cancer with peritoneal metastasis treated with chemotherapy and Korean medicine Methods: A patient with advanced gastric cancer with peritoneal metastasis was treated with Xeloda/cisplatin since April 2019. The cycle was repeated every three weeks for a total of 11 times. At the same time, the patient was treated with Korean medicine. The tumor size was measured by computed tomography (CT) and esophagogastroduodenoscopy (EGD). Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: After treatment with Xeloda/cisplatin and Korean medicine for nine months, the extent of the proximal portion of the primary tumor and the size and number of multiple nodules around the stomach decreased and the cancer cells with peritoneal metastasis disappeared. The symptoms of discomfort and physical activity were gradually improved. As a result, the patient underwent conversion surgery. Conclusions: This case study suggests that the combination of chemotherapy and Korean medicine may contribute to the reduction in tumor size as well as the improvement in the quality of life.
Abstract
Objectives: The purpose of this study was to report a case of a patient with advanced gastric cancer with peritoneal metastasis treated with chemotherapy and Korean medicine Methods: A patient with advanced gastric cancer with peritoneal metastasis was treated with Xeloda/cisplatin since April 2019. The cycle was repeated every three weeks for a total of 11 times. At the same time, the patient was treated with Korean medicine. The tumor size was measured by computed tomography (CT) and esophagogastroduodenoscopy (EGD). Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: After treatment with Xeloda/cisplatin and Korean medicine for nine months, the extent of the proximal portion of the primary tumor and the size and number of multiple nodules around the stomach decreased and the cancer cells with peritoneal metastasis disappeared. The symptoms of discomfort and physical activity were gradually improved. As a result, the patient underwent conversion surgery. Conclusions: This case study suggests that the combination of chemotherapy and Korean medicine may contribute to the reduction in tumor size as well as the improvement in the quality of life.
참고문헌 (35)
- "National Cancer Information Center" (2020)[URL]
- Katai H, "Early gastric cancer : concepts, diagnosis, and management", Int J Clin Oncol, 10(6), pp.375~383 (2005)
- Ono H, "Early gastric cancer : diagnosis, pathology, treatment techniques and treatment outcomes", Eur J Gastroenterol He-patol, 18(8), pp.863~866 (2006)
- "Gastric Cancer Treatment (PDQ®)–Patient Version" (2020)[URL]
- Registration Statistics-Statistical Information Report 2019, "Ministry of Health and Welfare", ~
- Morgagni P, "Conversion surgery for gastric cancer : A cohort study from a western center", International journal of surgery, 53, pp.360~365 (2018)
- 장성환, "한약치료와 표적항암요법(아피니토)을 병행하여 부분 관해 된 신세포암 간전이 환자 1례", 대한암한의학회지, 22(2), pp.13~24 (2017), 대한암한의학회[DOI]
- 이성재, "통합 의학적 암 치료", 식품기술, 20(3), pp.154~161 (2007)
- Smith TJ, "American Society of Clinical Oncology provisional clinical opinion:the integration of palliative care into standard oncology care", Journal of clinical oncology, 30(8), pp.880~887 (2012)
- National Comprehensive Cancer Network, "NCCN Guidelines for Patients-Stomach Cancer 2019", ~
- 김동희, "항암제(抗癌劑)부작용(副作 用)에 대한 한방요법(韓方療法)", 대전대학교 한의학 연구소 논문집, 2(1), pp.33~51 (1993)
- Sohaib A, "RECIST rules", Cancer Imaging, 12(2), pp.345~346 (2012)
- Watanabe H, "New Response Evaluation Criteria in Solid Tumours-Revised RECIST Guideline(version 1.1)", Cancer & chemotherapy, 36(13), pp.2495~2501 (2009)
- "Common Terminology Criteria for Adverse Events" (2020)[URL]
- 정희철, "위암의 맞춤 항암 요법의 최신 지견", 대한내과학회지, 77(1), pp.1~8 (2009), 대한내과학회
- 박중민, "Prognostic Factors for Advanced Gastric Cancer: Stagestratified Analysis of Patients w ho Underwent Curative Resection", Cancer Research and Treatment, 38(1), pp.13~18 (2006), 대한암학회
- Guideline Committee of the Korean Gastric Cancer Association, "Korean Practice Guideline for Gastric Cancer 2018; Evidence-based, Multi-disciplinary Approach", Journal of Gastric Cancer, 19(1), pp.1~48 (2019), 대한위암학회[DOI]
- 김효린, "위암 치료에 대한 한의 임상 가이드라인", 대한한방내과학회지, 37(1), pp.26~46 (2016), 대한한방내과학회
- Schmitz KH, "American College of Sports Medicine Roundtable on Exercise Guidelines for Cancer Survivors", Medicine and science in sports and exercise, 42(7), pp.1409~1426 (2010)
- Chen S, "Oral Chinese herbal medicine(CHM)as an adjuvant treatment during chemotherapy for non-small cell lung cancer : A systematic review", Lung cancer, 68(2), pp.137~145 (2010)
- 조종관, "면역에 관한 동양의학적 고찰", 동양의 학, 12(1), pp.19~23 (1986)
- 심범상, "A Literatural Study on Pattern Identification Type of Stomach Cancer", Korean Journal of Oriental Physiology & Pathology, 8(1), pp.295~303 (1993)
- Lee YW, "A study on the regimen for Gastroenteric disease", Journal of Hawhwa Medicine, 17(2), pp.1~15 (2008)
- 이혜연, "胃의 생리특성 및 胃氣와 眞藏脈과의 상관관계에 대한 연구", 대한한의학원전학회지, 24(4), pp.143~155 (2011), 대한한의학원전학회
- Lee DJ, "Experimental studies on anti-stress effects of Bohyulanshintang and Gamibohyulanshintang", Journal of oriental neuropsychiatry, 4(1), pp.77~97 (1993)
- 이성환, "알코올로 유발된 생쥐의 위점막손상에 대한 사물탕의 보호효과", 대한한의학회지, 25(3), pp.1~11 (2004), 대한한의학회
- Lee HS, "Network Pharmacology-Based Investigation of the System-Level Molecular Mechanisms of the Hematopoietic Activity of Samul-Tang, a Traditional Korean Herbal Formula", Evidence-based Complementary and Alternative Medicine (2020)
- 정종수, "Bojungikki-tang for cancer-related fatigue : a randomized, waiting list controlled trial", 석사, 내과학(한의학), pp.2010
- Kayo T, "Acupuncture for functional abdominal pain syndrome : a case report", Journal of the Japan society of acupuncture, 60(4), pp.744~751 (2010)
- Wong R, "Acupuncture treatment for chemotherapy-induced peripheral neuropathy-a case series", Acupuncture in medicine : journal of the British Medical Acupuncture Society, 24(2), pp.87~91 (2006)
- 임세영, "산삼약침이 Colon26-L5 암세포주를 이용한 간전이 모델의 항암 및 면역증진에 미치는 영향", Journal of Acupuncture Research, 23(1), pp.121~134 (2006), 대한침구의학회
- Toriyama-Baba H, "Organotropic Chemopreventive Effects of n-3 Unsaturated Fatty Acids in a Rat Multi-organ Carcinogenesis Model", Jpn J Cancer Res, 92(11), pp.1175~1183 (2001)
- Petrovich Z, "Radiotherapy in the management of locally advanced lung cancer of all cell types : final report of randomized trial", Cancer, 48(6), pp.1135~1140 (1981)
- Chen YM, "Update of epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancer", J Chin Med Assoc, 76(5), pp.249~257 (2013)
- Boku T, "Prognostic significance of serosal invasion and free intraperitoneal cancer cells in gastric cancer", British journal of surgery : BJS, 77(4), pp.436~439 (1990)