수술 및 항암 방사선 표준 치료 이후의 한양방 통합치료를 통해 5년 무병생존에 도달한 3기 직장암 환자 1례에 대한 보고
Case Report on the Five-year Survival of a Patient with Rectal Cancer Treated with Integrative Medicine After Resection and Chemoradiation Therapy
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Objectives: This is a five-year survival and complete response (CR) report on rectal cancer treated with western medicine and Korean traditional medicine. Method: A 25-year-old woman diagnosed with rectal cancer visited ⃝⃝ Korean traditional medicine hospital after neoadjuvant concurrent chemoradiation therapy, chemotherapy, and low anterior resection with regional lymph node dissection. She was treated with Korean traditional medicine, including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, and herbal medicine, which was based on integrated medicine therapy (IMT), from January 2018 to February 2022. The tumor size was measured by scanning with computed tomography (CT), magnetic resonance imaging, and positron-emission tomography/CT. Adverse events were evaluated using laboratory conclusion and National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0. Result: During four years of treatment, IMT maintained safety. The patient finally reached five-year survival without any recurrence or complication (CR) on March 11, 2022. Conclusion: We suggest that an integrative approach including Korean traditional medicine can be a meaningful treatment option for rectal cancer. Further studies should be performed to establish the proper treatment protocol of integrative medicine for rectal cancer.
Abstract
Objectives: This is a five-year survival and complete response (CR) report on rectal cancer treated with western medicine and Korean traditional medicine. Method: A 25-year-old woman diagnosed with rectal cancer visited ⃝⃝ Korean traditional medicine hospital after neoadjuvant concurrent chemoradiation therapy, chemotherapy, and low anterior resection with regional lymph node dissection. She was treated with Korean traditional medicine, including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, and herbal medicine, which was based on integrated medicine therapy (IMT), from January 2018 to February 2022. The tumor size was measured by scanning with computed tomography (CT), magnetic resonance imaging, and positron-emission tomography/CT. Adverse events were evaluated using laboratory conclusion and National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0. Result: During four years of treatment, IMT maintained safety. The patient finally reached five-year survival without any recurrence or complication (CR) on March 11, 2022. Conclusion: We suggest that an integrative approach including Korean traditional medicine can be a meaningful treatment option for rectal cancer. Further studies should be performed to establish the proper treatment protocol of integrative medicine for rectal cancer.
참고문헌 (16)
- "보건복지부 증앙암등록본부 2022년 12월 발표자료", ~ (2022)
- 대한의학회, "대장암진료권고안v1.0", ~ (2012)
- Wiggers T, "Surgery for loal recurrence of rectal carcinoma", Dis Colon Rectum, 39(3), pp.323~328 (1996)
- Gray R, "Adjuvant chemotherapy versus observation in patients with colorectal cancer : a randomized study", Lancet, 370(9604), pp.2020~2029 (2007)
- 방선휘, "A Clinical Observation of Oriental Medicine-Based Long Care for Terminal Rectal Cancer Patient with Multiple Metastasis", 대한한방내과학회지, 29(3), pp.567~573 (2008), 대한한방내과학회
- Garaci E, "Historical review on thymosin α1 in oncology : preclinical and clinical experiences", Expert Opin Biol Ther, 15(Suppl 1), pp.S31~S39 (2015)
- Fritz H, "Intravenous Vitamin C and cancer : A Systemic review", Intergr cancer Ther, 13(4), pp.280~300 (2014)
- Kienle GS, "Complementary cancer therapy : a systematic review of prospective clinical trials on anthroposophic mistletoe extracts", Eur J Med Res, 12(3), pp.103~119 (2007)
- 赵昌风, "针灸对结肠癌肝转移患者外周T淋巴细胞亚群NK细胞活性的影响", 中国针灸, 30(1), pp.10~12 (2010)
- Hosseinzade A, "Immunomodulatory Effects of Flavonoids : Possible Induction of T CD4+ Regulatory Cells Through Suppression of mTOR Pathway Signaling Activity", Front Immunol, 10, pp.51~ (2019)
- Dai D, "Ginseng on Cancer : Potential Role in Modulating Inflammation-mediated Angiogenesis", Am J Chin Med, 45(1), pp.13~22 (2017)
- Staib L, "Follow up in colorectal cancer : cost-effectiveness analysis of established and novel concepts", Langenbecks Arch Surg, 385(6), pp.412~420 (2000)
- 김남규, "대장 직장암의 근치적 절제술 후 재발양상과 생존율에 영향을 미치는 예후인자 분석", Annals of Surgical Treatment and Research, 62(5), pp.421~429 (2002), 대한외과학회
- Wong CS, "Combined radiation therapy, Mitomycin C, and 5-fluorouracil for locally recurrent rectal carcinoma. Results of a pilot study", Int J Radiat Oncol Biol Phys, 21(5), pp.1291~1296 (1991)
- Wong CS, "Treatment of locally recurrent rectal carcinoma-Results and Prognostic factors", Int J Radiat Oncol Biol Phys, 40(2), pp.427~435 (1998)
- Hocht S, "Recurrent rectal cancer within the pelvis : a multicenter analysis of 123 patients and recommendations for adjuvant radiotherapy", Strahlenther Onkol, 180(1), pp.15~20 (2004)