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Effect of Three Seaweed Extracts Prepared Using High Hydrostatic Pressure on Anti-Obesity Activity in Mice Fed a High-Fat Diet
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We examined the effects of three seaweed extracts prepared using high hydrostatic pressure (HHP) extraction on antiobesity activity in mice fed a high-fat diet. The extraction yields of LH (laver extract produced by HHP processes), SCH (sea cabbage extract produced by HHP processes) and SMH (sea mustard extract produced by HHP processes) from HHP treatment were 11.32%, 28.61%, and 12.05%, respectively, with desalinated sea cabbage exhibiting the highest extraction efficiency. The body weights of mice fed a high-fat diet supplemented with seaweed extracts were monitored, and after 5 weeks, the body weight of the SMH group was 18.95 g. The triglyceride levels in the SCH and SMH groups were 106.55 and 100.40 mg/dL respectively, while the SCC group showed the highest triglyceride and high-density lipoprotein cholesterol levels. The LH group had the lowest levels of low-density lipoprotein cholesterol levels among the extract-treated groups. The glucose levels in the SCC and SMH groups were 155.81 and 263.56 mg/ dL, respectively. Histological differences were observed in the liver and adipose tissues of mice fed a high-fat diet supplemented with seaweed extracts compared with those of mice fed only a high-fat diet.
Abstract
We examined the effects of three seaweed extracts prepared using high hydrostatic pressure (HHP) extraction on antiobesity activity in mice fed a high-fat diet. The extraction yields of LH (laver extract produced by HHP processes), SCH (sea cabbage extract produced by HHP processes) and SMH (sea mustard extract produced by HHP processes) from HHP treatment were 11.32%, 28.61%, and 12.05%, respectively, with desalinated sea cabbage exhibiting the highest extraction efficiency. The body weights of mice fed a high-fat diet supplemented with seaweed extracts were monitored, and after 5 weeks, the body weight of the SMH group was 18.95 g. The triglyceride levels in the SCH and SMH groups were 106.55 and 100.40 mg/dL respectively, while the SCC group showed the highest triglyceride and high-density lipoprotein cholesterol levels. The LH group had the lowest levels of low-density lipoprotein cholesterol levels among the extract-treated groups. The glucose levels in the SCC and SMH groups were 155.81 and 263.56 mg/ dL, respectively. Histological differences were observed in the liver and adipose tissues of mice fed a high-fat diet supplemented with seaweed extracts compared with those of mice fed only a high-fat diet.