본문 바로가기
KERD
논문KCI 등재

항암화학요법과 병행한 한의기반 통합암치료를 통한 전이성 비소세포폐암 환자의 암성 통증 호전 증례보고

A Case Report on the Improvement of Cancer Pain in a Patient with Metastatic Non-Small Cell Lung Cancer Through Herbal Medicine-based Integrative Cancer Treatment with Chemotherapy

3

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류한의학

초록

Objective: To demonstrate an improvement in metastatic cancer pain and a decrease in tumor size in a patient with non-small cell lung cancer. Method: A 53-year-old female patient diagnosed with metastatic non-small cell lung cancer in August 2022 underwent integrative cancer treatment (ICT) for two months to decrease the tumor size and improve back pain from bone metastasis. The patient underwent chemotherapy with ICT. Radiologic outcomes were assessed by chest, abdomen, and pelvis computed tomography based on the Response Evaluation Criteria in Solid Tumors (RECIST) protocol. Clinical outcomes were assessed using National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Eastern Cooperative Oncology Group (ECOG), and a numeric rating scale (NRS). Result: During the two months of treatment, the NRS scores for back pain were improved, and the ECOG score improved from grade 2 to 1. The size and metabolic activity of the primary lung tumor decreased and underwent partial remission based on RECIST. No serious side effects of grade 3 or higher were noted on the NCI-CTCAE test. Conclusion: This case suggests that ICT may have a therapeutic effect for cancer pain and a synergetic effect with chemotherapy for metastatic non-small cell lung cancer.

Abstract

Objective: To demonstrate an improvement in metastatic cancer pain and a decrease in tumor size in a patient with non-small cell lung cancer. Method: A 53-year-old female patient diagnosed with metastatic non-small cell lung cancer in August 2022 underwent integrative cancer treatment (ICT) for two months to decrease the tumor size and improve back pain from bone metastasis. The patient underwent chemotherapy with ICT. Radiologic outcomes were assessed by chest, abdomen, and pelvis computed tomography based on the Response Evaluation Criteria in Solid Tumors (RECIST) protocol. Clinical outcomes were assessed using National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Eastern Cooperative Oncology Group (ECOG), and a numeric rating scale (NRS). Result: During the two months of treatment, the NRS scores for back pain were improved, and the ECOG score improved from grade 2 to 1. The size and metabolic activity of the primary lung tumor decreased and underwent partial remission based on RECIST. No serious side effects of grade 3 or higher were noted on the NCI-CTCAE test. Conclusion: This case suggests that ICT may have a therapeutic effect for cancer pain and a synergetic effect with chemotherapy for metastatic non-small cell lung cancer.

참고문헌 (15)

  1. Annual report of cancer statistics in Korea in 2020, "Ministry of Health and Welfare", 1~57 (2020)
  2. "World Cancer Research Fund International" (2020)[URL]
  3. "National Cancer Information center"[URL]
  4. Subramanian J, "Lung cancer in never smokers : a review", J Clin Oncol, 25(5), pp.561~570 (2007)[DOI]
  5. SEER Incidence Data, "November 2022 Submission (1975-2020), SEER 22 registries (excluding Illinois and Massachusetts)", ~ (2022)
  6. Brouns A, "Non-Radiation Based Early Pain Relief Treatment Options for Patients with Non-Small Cell Lung Cancer and Cancer Induced Bone Pain : A Systematic Review", Front Oncol, 10, pp.509297~ (2020)[DOI]
  7. 곽상규, "논문 리뷰를 통한 암성통증에 대한 침을 이용한 양한방 통합치료 효과 연구", 한국데이터정보과학회지, 26(6), pp.1327~1334 (2015), 한국데이터정보과학회[DOI]
  8. Park BK, "Retrospective Cohort Analysis for Lung Cancer Patients Treated with Wheel Balance, Therapy (WBT)", J Int Korean Med, (spr), pp.45~56 (2008)
  9. Kim YW, "Early detection of lung cancer", Korean J Intern Med, 65(1), pp.4~9 (2003)
  10. Alessandro Del C, "Bone Metastasis and Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer(NSCLC) : Microenvironment and Possible Clinical Implications", Int J Mol Sci, 23(12), pp.6832~ (2022)[DOI]
  11. Gül G, "A comprehensive review of denosumab for bone metastasis in patients with solid tumors", Curr Med Res Opin, 32(1), pp.133~145 (2016)[DOI]
  12. Zhao LH, "Neuropharmacological effects of Aconiti Lateralis Radix Praeparata", Clin Exp Pharmacol Physiol, 47(4), pp.531~542 (2020)[DOI]
  13. Oriental medical schools Herbology Compilation Committee, "Herbology", pp.311~466 (2007), Yeongrimsa
  14. 윤미정, "비소세포성 폐암의 척추 전이로 발생한 암성통증에 대한 초오 약침을 포함한 한방 치료 1례", 대한암한의학회지, 24(2), pp.33~41 (2019), 대한암한의학회[DOI]
  15. Song SY, "Synergistic Effect of HAD-B1 and Afatinib Against Gefitinib Resistance of Non-Small Cell Lung Cancer", Integr Cancer Ther, 21, pp.15347354221144311~ (2022)[DOI]

관련 논문AI추천

전이성 4기 대장암 환자의 한의기반 통합암치료를 통한 증상 호전 증례보고김종희, 박소정, 박지혜, 오현묵, 유화승대한한방내과학회 · 대한한방내과학회지2020 · 제41권 제6호재발된 자궁경부암 환자의 한의 기반 통합 암 치료에 대한 증례보고박소정, 박지혜, 송시연, 유화승, 조영민, 주한음대한한방내과학회 · 대한한방내과학회지2022 · 제43권 제4호고령의 비소세포폐암(Non-small cell lung cancer) 환자를 대상으로 한 한양방 복합 치험 2례김관일, 이민준, 이범준, 정희재, 진수현, 진하윤, 최대준대한한방내과학회 · 대한한방내과학회지2025 · 제46권 제3호한의학적 치료로 호전된 전이성 대장암 환자의 복통에 대한 증례보고김경순, 김나연, 김승모, 윤미정, 최홍식대한한방내과학회 · 대한한방내과학회지2021 · 제42권 제4호한의기반 통합암치료를 통한 재발성 담낭암 환자의 증상 호전 증례보고고은주, 도성국, 박지혜, 송시연, 유화승, 이연월대한한방내과학회 · 대한한방내과학회지2022 · 제43권 제3호Pembrolizumab 면역치료를 시행 중인 비소세포성 폐암환자의 한방치료 증례보고이인, 이찬, 권정남, 김소연, 박성하, 서형범, 서희정, 심소현, 윤영주, 조임학, 최준용, 한창우, 홍진우대한한방내과학회 · 대한한방내과학회지2019 · 제40권 제4호

이 간행물의 다른 논문 (20건)