본문 바로가기
KERD
논문KCI 등재

급성 횡단성 척수염으로 의심된 길랑바레증후군 환자에 대한 한방 치료 증례보고 1례

A Case Report of a Guillain-Barre Syndrome Patient Suspected of Having Acute Transverse Myelitis Treated with Korean Medicine

1

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류한의학

초록

A 67-year-old female patient diagnosed with acute transverse myelitis visited our hospital in February 2023. Consultation papers indicated that she was diagnosed with acute transverse myelitis and that she complained of quadriparesis and numbness in both hands and feet. However, her spine magnetic resonance imaging (MRI) did not clearly indicate that she suffered from acute transverse myelitis. She was then sent to a high-level hospital and diagnosed with Guillain-Barre Syndrome through electromyography, cerebrospinal fluid test, and spine MRI. On March 2023, she visited our hospital again, still complaining about weakness in both hands and inability to walk. She was treated with Korean medicine, including acupuncture, electroacupuncture, pharmacopuncture, and herbal medicine such as Yanggyeoksanhwatang and Sipimijihwang-tanggami. After three months, she was discharged on cane walking. The manual muscle test (MMT) grade of her upper limbs increased from 3-/3-/3-/3- (shoulder/elbow/wrist/fingers) to 4/4/4/3+, and the MMT grade of her lower limbs increased from 2/2/2/2 (pelvis/knee/ankle/feet) to 4/4/4-/4-. Her numbness in both feet disappeared, and her numbness in both hands decreased from a numeric rating scale of 7 to 2. No adverse events were reported during treatment. This case implies the therapeutic potential of Korean medicine for Guillain-Barre Syndrome, especially for those who had delayed diagnosis and missed the opportunity to get plasma exchange.

Abstract

A 67-year-old female patient diagnosed with acute transverse myelitis visited our hospital in February 2023. Consultation papers indicated that she was diagnosed with acute transverse myelitis and that she complained of quadriparesis and numbness in both hands and feet. However, her spine magnetic resonance imaging (MRI) did not clearly indicate that she suffered from acute transverse myelitis. She was then sent to a high-level hospital and diagnosed with Guillain-Barre Syndrome through electromyography, cerebrospinal fluid test, and spine MRI. On March 2023, she visited our hospital again, still complaining about weakness in both hands and inability to walk. She was treated with Korean medicine, including acupuncture, electroacupuncture, pharmacopuncture, and herbal medicine such as Yanggyeoksanhwatang and Sipimijihwang-tanggami. After three months, she was discharged on cane walking. The manual muscle test (MMT) grade of her upper limbs increased from 3-/3-/3-/3- (shoulder/elbow/wrist/fingers) to 4/4/4/3+, and the MMT grade of her lower limbs increased from 2/2/2/2 (pelvis/knee/ankle/feet) to 4/4/4-/4-. Her numbness in both feet disappeared, and her numbness in both hands decreased from a numeric rating scale of 7 to 2. No adverse events were reported during treatment. This case implies the therapeutic potential of Korean medicine for Guillain-Barre Syndrome, especially for those who had delayed diagnosis and missed the opportunity to get plasma exchange.

참고문헌 (24)

  1. Guillain G, "Sur un syndrome de radiculo-nevrite avec hyperalbuminose du liquode cephalo-rachidien sans reaction cellulaire : remarques sur les caracteres cliniques et graphiques des reflexes tendineux", Bell Mem Soc Med Paris, 40, pp.1462~1470 (1916)
  2. Rho JK, "A Clinical Study on Guillain-Barr'e Syndrome", J Korean Neurol Assoc, 2(1), pp.3~13 (1984)
  3. Fauci A, "Harrison's Principles of Internal Medicine", pp.3203~3207 (2010), MIP
  4. Van Doorn PA, "Clinical features, pathogenesis, and treatment of Guillain-Barre syndrome", Lancet Neurol, 7(10), pp.939~950 (2008)
  5. 윤별아, "길랭-바레증후군의 최신 지견", 대한신경과학회지, 37(1), pp.8~19 (2019), 대한신경과학회[DOI]
  6. Kerr DA, "Immunopathogenesis of acute trans-verse myelitis", Curr Opin Neurol, 15(3), pp.339~347 (2002)
  7. Bhat A, "The epidemiology of transverse myelitis", Autoimmun Rev, 9(5), pp.A395~A399 (2010)
  8. Journal of Clinical Neurology, "Textbook of Neurology volume 3", pp.66~ (2011), panmuneducation
  9. Hartrick CT, "The numeric rating scale for clinical pain measurement: a ratio measure?", Pain Pract, 3(4), pp.310~316 (2003)
  10. 이보련, "소아기 급성 횡단성 척수염의 임상적 고찰", 대한소아신경학회지, 16(1), pp.50~61 (2008), 대한소아신경학회
  11. Park WK, "MRI Findings of Guillain-Barré Syndrome", J Korean Radiol Soc, 36, pp.561~565 (1997)
  12. Association of Korean Medicine College for Cardiology and Neurological Medicine, "Cardiovascular and Neurological Medicine in Korean Medicine", pp.289~304 (2020), Gunjapublisher
  13. 김형중, "길랑바레 증후군의 한방치료에 관한 고찰 –중의학 저널을 중심으로–", 대한한방소아과학회지, 29(3), pp.21~31 (2015), 대한한방소아과학회
  14. 김정열, "중풍환자의 胸中煩熱症에 대한 凉膈散火湯 투여 2例", 대한한방내과학회지, 23(2), pp.292~297 (2002), 대한한방내과학회
  15. 정다영, "소양인 양격산화탕의 면역 활성화 연구", 사상체질의학회지, 22(4), pp.77~84 (2010), 사상체질의학회
  16. Zhang XY, "Comparing steamed and wine-stewed Rehmanniae Radix in terms of Yin-nourishing effects via metabolomics and microbiome analysis", Journal of Ethnopharmacology, 311, pp.116424~ (2023)
  17. Ma JY, "Shibimijihwang-tang elevates intracellular ATP and choline content in the cerebral cortex of ovariectomized rats", J Ethnopharmacol, 72(1-2), pp.77~85 (2000)
  18. Liu SW, "Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula : A Randomized Controlled Trial", Chin J Integr Med, 25(1), pp.16~22 (2019)
  19. Wui YL, "Se-euideukhyobang", pp.307~ (1997), Shanghai Scientific & Technical Publishers
  20. 홍초영, "천왕보심단(天王補心丹)∘쌀발효추출물(GABAːgamma-aminobutyric acid 30%) 복합물의 抗스트레스에 대한 유효성 연구ː무작위 배정 및 이중맹검", 대한본초학회지, 38(2), pp.1~8 (2023), 대한본초학회
  21. 박만용, "痿證의 침구 치료에 대한 문헌 고찰", 동의생리병리학회지, 26(6), pp.842~848 (2012), 한의병리학회
  22. 김현지, "봉약침의 임상 응용에 대한 체계적 문헌 고찰", Journal of Acupuncture Research, 30(4), pp.151~159 (2013), 대한침구의학회[DOI]
  23. 최윤정, "척수염과 병발한 길랑-바레증후군 1예", 대한신경과학회지, 23(1), pp.124~127 (2005), 대한신경과학회
  24. 이동국, "급성 운동축삭성 길랑-바레 증후군과 동반된 급성 경수-상흉수 횡다성 척수염 1예", Annals of Clinical Neurophysiology, 3(2), pp.172~175 (2001), 대한임상신경생리학회

관련 논문AI추천

사지마비와 저림을 호소하는 길랑바레 증후군 환자의 한방치료 증례보고 1례김두리, 문병순, 백동기, 심상송, 윤종민, 이현승대한한방내과학회 · 대한한방내과학회지2019 · 제40권 제6호사지위약감과 안면마비를 주소로 하는 길랑바레 증후군 환자의 한방치료 증례보고 1례김윤식, 김정희, 김해융, 설인찬, 원서영, 유주영, 유호룡, 정은선대한한방내과학회 · 대한한방내과학회지2021 · 제42권 제4호사지마비와 식욕부진을 호소하는 길랑바레 증후군 환자의 한방치료 증례보고 1례정솔, 문병순, 신용진, 심상송, 안재윤, 윤종민대한한방내과학회 · 대한한방내과학회지2020 · 제41권 제5호사지마비를 주소로 하는 길랑바레 증후군 환자에 대한 증례보고 1례이인, 이찬, 강희경, 권정남, 김민화, 김소연, 박성하, 윤영주, 조임학, 최준용, 한창우, 허기윤, 홍진우대한한방내과학회 · 대한한방내과학회지2021 · 제42권 제5호침 치료 및 전침 치료로 호전된 길랑바레증후군 환자의 균형 및 보행 개선 : 증례보고강선이, 김지우, 김철현, 소영조, 이상관, 지상호대한한방내과학회 · 대한한방내과학회지2024 · 제45권 제2호길랑바레증후군으로 진단받은 환자의 한방치료 증례보고 1례김은지, 김재영, 박삼민, 황동규대한한방내과학회 · 대한한방내과학회지2016 · 제37권 제2호

이 간행물의 다른 논문 (17건)