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KERD
논문KCI 등재

Microarray Applications in Cancer Research

Jae-Gahb Park|Il-Jin Kim|Hio Chung Kang
대한암학회 (Korean Cancer Association)|2004.08|Cancer Research and Treatment|제36권 제4호|pp. 207-213

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초록

Abstract

DNA microarray technology permits simultaneous analysis of thousands of DNA sequences for genomic research and diagnostics applications. Microarray technology represents the most recent and exciting advance in the application of hybridization-based technology for biological sciences analysis. This review focuses on the classification (oligonucleotide vs. cDNA) and application (mutation-genotyping vs. gene expression) of microarrays. Oligonucleotide microarrays can be used both in mutation-genotyping and gene expression analysis, while cDNA microarrays can only be used in gene expression analysis. We review microarray mutation analysis,including examining the use of three oligonucleotide microarrays developed in our laboratory to determine mutations in RET, beta-catenin and K-ras genes. We also discuss the use of the Affymetrix GeneChip in mutation analysis. We review microarray gene expression analysis, including the classifying of such studies into four categories: class comparison, class prediction, class discovery and identification of biomarkers.(Cancer Res Treat. 2004;36:207-213)

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관련 논문AI추천

Role of Microarray in Cancer DiagnosisHoguen Kim대한암학회 · Cancer Research and Treatment2004 · 제36권 제1호Gene Expression Profiling of Non-Small Cell Lung CancerChoon Hee Son, Dae Cheol Kim, Hyo Jin Kim, Hyuk Chan Kwon, Jae Ik Lee, Jin Han Yoon, Jin Sook Jeong, Ki Nam Lee, Mee Sook Roh, Phil Jo Choi, Soo Keol Lee, Tae Ho Hwang대한암학회 · Cancer Research and Treatment2003 · 제35권 제2호cDNA Microarray Analysis of Differential Gene Expression in Gastric Cancer Cells Sensitive and Resistant to 5-Fluorouracil and Cisplatin안명주, 안준익, 오호석, 유동현, 유영도, 이기환, 이용성, 이혜숙, 최정혜대한암학회 · Cancer Research and Treatment2005 · 제37권 제1호The Differential Gene Expression Profiles between Sensitive and Resistant Breast Cancer Cells to Adriamycin by cDNA Microarray배준민, 안명주, 안준익, 유동현, 이기환, 이용성, 이혜숙, 장정순, 최정혜대한암학회 · Cancer Research and Treatment2004 · 제36권 제1호Medical Implementation of Microarray TechnologyJi Un Kang대한임상검사과학회 · 대한임상검사과학회지2020 · 제52권 제4호Evaluation of Microarray Sensitivity for DNA ProfilingJoo-Woon Lee대한화학회 · 대한화학회지2012 · 제56권 제4호

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