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Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer

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초록

We report on a patient with brain metastasis involving bilateral internal auditory canalfrom non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosedwith NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitusfor three months. The patient had refused all treatments, including surgery andchemotherapy; however, she sought alternative medicine. The patient’s hearing lossshowed rapid progression bilaterally, and rotatory vertigo with peripheral-type nystagmusdeveloped. Magnetic resonance imaging of the brain showed irregular nodularenhancement within both internal auditory canals with leptomeningeal enhancementand multiple intracranial metastasis. The patient was treated with epidermal growthfactor receptor􀀂tyrosine kinase inhibitor, and the tumor showed partial response. Thiswas a rare case of multiple brain metastases involving bilateral internal auditory canalfrom known NSCLC presenting with vertigo and hearing loss.

Abstract

We report on a patient with brain metastasis involving bilateral internal auditory canalfrom non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosedwith NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitusfor three months. The patient had refused all treatments, including surgery andchemotherapy; however, she sought alternative medicine. The patient’s hearing lossshowed rapid progression bilaterally, and rotatory vertigo with peripheral-type nystagmusdeveloped. Magnetic resonance imaging of the brain showed irregular nodularenhancement within both internal auditory canals with leptomeningeal enhancementand multiple intracranial metastasis. The patient was treated with epidermal growthfactor receptor􀀂tyrosine kinase inhibitor, and the tumor showed partial response. Thiswas a rare case of multiple brain metastases involving bilateral internal auditory canalfrom known NSCLC presenting with vertigo and hearing loss.

참고문헌 (13)

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