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Cancer Incidence and Survival among Adolescents and Young Adults in Korea: An Update for 2016

원영주|박현진|임지원|이준아|박병규|정규원|박미림
대한암학회 (Korean Cancer Association)|2021.01|Cancer Research and Treatment|제53권 제1호|pp. 32-44|DOI 10.4143/crt.2020.644

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키워드

KoreaIncidenceSurvivalNeoplasmsAdolescent and young adult
주제분류의학일반

초록

Purpose This study investigated the incidence and relative survival rates (RSRs) for cancers among adolescents and young adults (AYAs) aged 15-39 years between 1993 and 2016 in Korea. Materials and Methods Data from the Korea Central Cancer Registry were used to calculate percent distributions, age-specific incidence rates, age-standardized incidence rates (ASRs) per million, annual percent changes (APCs), average APCs, and RSRs for cancers diagnosed in AYAs. Results ASR of all cancers among AYAs was 654.5 per million. The largest diagnosed group of cancers was carcinomas (almost 80%). Crude incidence increased with age, from 170.4 per million for those aged 15-19 years to 1,639.8 per million for those aged 35-39 years. ASR increased from 414.8 per million to 820.4 per million, with an APC of 9.0%. The incidence of thyroid carcinoma showed the most rapid increment (APC, 14.0%), followed by non-Hodgkin lymphoma (APC, 13.4%). The 5-year RSR among AYAs significantly improved from 62.1% to 90.8%. Survival improvement in AYAs was higher than that in children but lower than that in older adults (APC, 2.1% vs. 1.9% vs. 3.1%). The most marked survival improvement was found for leukemia and lymphoma. Astrocytoma, rhabdomyosarcoma, and carcinoma of the trachea, bronchus, and lung had a 5-year RSR of < 50%. Conclusion There was an improvement in cancer survivals in AYAs, comparable to that achieved in children. However, survivals in several cancer types do not appear to be improving. Further research focusing on the epidemiology and therapeutic strategies for cancers in AYAs is needed.

Abstract

Purpose This study investigated the incidence and relative survival rates (RSRs) for cancers among adolescents and young adults (AYAs) aged 15-39 years between 1993 and 2016 in Korea. Materials and Methods Data from the Korea Central Cancer Registry were used to calculate percent distributions, age-specific incidence rates, age-standardized incidence rates (ASRs) per million, annual percent changes (APCs), average APCs, and RSRs for cancers diagnosed in AYAs. Results ASR of all cancers among AYAs was 654.5 per million. The largest diagnosed group of cancers was carcinomas (almost 80%). Crude incidence increased with age, from 170.4 per million for those aged 15-19 years to 1,639.8 per million for those aged 35-39 years. ASR increased from 414.8 per million to 820.4 per million, with an APC of 9.0%. The incidence of thyroid carcinoma showed the most rapid increment (APC, 14.0%), followed by non-Hodgkin lymphoma (APC, 13.4%). The 5-year RSR among AYAs significantly improved from 62.1% to 90.8%. Survival improvement in AYAs was higher than that in children but lower than that in older adults (APC, 2.1% vs. 1.9% vs. 3.1%). The most marked survival improvement was found for leukemia and lymphoma. Astrocytoma, rhabdomyosarcoma, and carcinoma of the trachea, bronchus, and lung had a 5-year RSR of < 50%. Conclusion There was an improvement in cancer survivals in AYAs, comparable to that achieved in children. However, survivals in several cancer types do not appear to be improving. Further research focusing on the epidemiology and therapeutic strategies for cancers in AYAs is needed.

참고문헌 (36)

  1. Arnett JJ, "Emerging adulthood. A theory of development from the late teens through the twenties", Am Psychol, 55, pp.469~480 (2000)
  2. U.S. Department of Health and Human Services, "Adolescent and Young Adult Oncology Progress Review Group: closing the gap: research and care imperatives for adolescents and young adults with cancer" (2006), National Cancer Institute
  3. Desandes E, "Epidemiology of adolescents and young adults with cancer in Europe", Prog Tumor Res, 43, pp.1~15 (2016)
  4. Bleyer A, "Young adult oncology : the patients and their survival challenges", CA Cancer J Clin, 57, pp.242~255 (2007)
  5. Burke ME, "Challenges in the recruitment of adolescents and young adults to cancer clinical trials", Cancer, 110, pp.2385~2393 (2007)
  6. Bleyer A, "Relative lack of conditional survival improvement in young adults with cancer", Semin Oncol, 36, pp.460~467 (2009)
  7. Gatta G, "Survival of European children and young adults with cancer diagnosed 1995-2002", Eur J Cancer, 45, pp.992~1005 (2009)
  8. Keegan TH, "Comparison of cancer survival trends in the United States of adolescents and young adults with those in children and older adults", Cancer, 122, pp.1009~1016 (2016)
  9. Bleyer A, "Global assessment of cancer incidence and survival in adolescents and young adults", Pediatr Blood Cancer, 64, pp.e26497~ (2017)
  10. 정규원, "Cancer Statistics in Korea: Incidence, Mortality, Survival and Prevalence in 2010", Cancer Research and Treatment, 45(1), pp.1~14 (2013), 대한암학회[DOI]
  11. Stark D, "Teenagers and young adults with cancer in Europe : from national programmes to a European integrated coordinated project", Eur J Cancer Care(Engl), 25, pp.419~427 (2016)
  12. Moon EK, "Cancer incidence and survival among adolescents and young adults in Korea", PLoS One, 9, pp.e96088~ (2014)
  13. Fritz A, "International Classification of Diseases for Oncology" (2000), World Health Organization
  14. Bleyer A, "Cancer epidemiology in older adolescents and young adults 15 to 29 years of age, including SEER incidece and survival: 1975-2000" (2006), National Cancer Institute
  15. Barr RD, "Classification schemes for tumors diagnosed in adolescents and young adults", Cancer, 106, pp.1425~1430 (2006)
  16. "SEER Cancer Statistics Review, 1975-2010" (2013)[URL]
  17. Brenner H, "Deriving more up-to-date estimates of long-term patient survival", J Clin Epidemiol, 50, pp.211~216 (1997)
  18. Kim HJ, "Permutation tests for joinpoint regression with applications to cancer rates", Stat Med, 19, pp.335~351 (2000)
  19. Barr RD, "Cancer in adolescents and young adults : a narrative review of the current status and a view of the future", JAMA Pediatr, 170, pp.495~501 (2016)
  20. Trama A, "Survival of European adolescents and young adults diagnosed with cancer in 2000-07 : population-based data from EUROCARE-5", Lancet Oncol, 17, pp.896~906 (2016)
  21. Alston RD, "Changes in cancer incidence in teenagers and young adults(ages 13 to 24 years)in England 1979-2003", Cancer, 113, pp.2807~2815 (2008)
  22. Marrett LD, "Cancer incidence in young adults in Canada: preliminary results of a cancer surveillance project", Chronic Dis Can, 23, pp.58~64 (2002)
  23. Hogan AR, "Pediatric thyroid carcinoma : incidence and outcomes in 1753patients", J Surg Res, 156, pp.167~172 (2009)
  24. Berkun L, "Cancer incidence and survival among adolescents in Israel during the years 1998 to 2009", Pediatr Blood Cancer, 60, pp.1848~1854 (2013)
  25. Lee JH, "Overdiagnosis and screening for thyroid cancer in Korea", Lancet, 384, pp.1848~ (2014)
  26. Cook MB, "Sex disparities in cancer mortality and survival", Cancer Epidemiol Biomarkers Prev, 20, pp.1629~1637 (2011)
  27. Derwahl M, "Estrogen and its role in thyroid cancer", Endocr Relat Cancer, 21, pp.T273~83 (2014)
  28. Rahbari R, "Thyroid cancer gender disparity", Future Oncol, 6, pp.1771~1779 (2010)
  29. Rebai M, "Association of polymorphisms in estrogen and thyroid hormone receptors with thyroid cancer risk", J Recept Signal Transduct Res, 29, pp.113~118 (2009)
  30. Rajoria S, "Metastatic phenotype is regulated by estrogen in thyroid cells", Thyroid, 20, pp.33~41 (2010)
  31. 박현진, "Incidence and Survival of Childhood Cancer in Korea", Cancer Research and Treatment, 48(3), pp.869~882 (2016), 대한암학회
  32. Tichy JR, "Breast cancer in adolescents and young adults : a review with a focus on biology", J Natl Compr Canc Netw, 11, pp.1060~1069 (2013)
  33. Johnson RH, "Breast cancer in adolescents and young adults", Pediatr Blood Cancer, 65, pp.e27397~ (2018)
  34. Gondos A, "Survival among adolescents and young adults with cancer in Germany and the United States : an international comparison", Int J Cancer, 133, pp.2207~2215 (2013)
  35. Bleyer A, "The distinctive biology of cancer in adolescents and young adults", Nat Rev Cancer, 8, pp.288~298 (2008)
  36. Ferreira CG, "The adolescent and young adult with cancer : state of the art : epithelial cancer", Curr Oncol Rep, 15, pp.287~295 (2013)

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