Relief of Postherpetic Neuralgia with Transforaminal Epidural Injection of Magnesium -A Case Report-
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Although postherpetic neuralgia (PHN) is a common chronic pain syndrome, the pathophysiology of this disorder is not well known and management is often very difficult. N-methyl-D-Aspartate (NMDA) receptor antagonists are known to be effective in PHN, and magnesium, a physiological blocker of NMDA receptors, is widely used to treat various chronic pain disorders. Here, we present a case of the PHN refractory to conventional treatment, which was treated successfully with transforaminal epidural injection of magnesium sulphate at the affected dermatome.
Abstract
Although postherpetic neuralgia (PHN) is a common chronic pain syndrome, the pathophysiology of this disorder is not well known and management is often very difficult. N-methyl-D-Aspartate (NMDA) receptor antagonists are known to be effective in PHN, and magnesium, a physiological blocker of NMDA receptors, is widely used to treat various chronic pain disorders. Here, we present a case of the PHN refractory to conventional treatment, which was treated successfully with transforaminal epidural injection of magnesium sulphate at the affected dermatome.
참고문헌 (17)
- Loeser JD, "Herpes zoster and postherpetic neuralgia", Pain, 25, pp.149~164 (1986)
- Kost RG, "Postherpetic neuralgia--pathogenesis, treatment, and prevention", N Engl J Med, 335, pp.32~42 (1996)
- Eide PK, "Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross- over comparison with morphine and placebo", Pain, 58, pp.347~354 (1994)
- Arcioni R, "Combined intrathecal and epidural magnesium sulfate supplementation of spinal anesthesia to reduce post-operative analgesic requirements: a prospective, randomized, double- blind, controlled trial in patients undergoing major orthopedic surgery", Acta Anaesthesiol Scand, 51, pp.482~489 (2007)
- Eide PK, "Central dysesthesia pain after traumatic spinal cord injury is dependent on N-methyl-D-aspartate receptor activation", Neurosurgery, 37, pp.1080~1087 (1995)
- Crosby V, "The safety and efficacy of a single dose (500 mg or 1 g) of intravenous magnesium sulfate in neuropathic pain poorly responsive to strong opioid analgesics in patients with cancer", J Pain Symptom Manage, 19, pp.35~39 (2000)
- Brill S, "Efficacy of intravenous magnesium in neuropathic pain", Br J Anaesth, 89, pp.711~714 (2002)
- Demirkaya S, "Efficacy of intravenous magnesium sulfate in the treatment of acute migraine attacks", Headache, 41, pp.171~177 (2001)
- Collins S, "Intravenous magnesium for complex regional pain syndrome type 1 (CRPS 1) patients: a pilot study", Pain Med, 10, pp.930~940 (2009)
- Oppelt WW, "Magnesium exchange between blood and cerebrospinal fluid", Am J Physiol, 205, pp.959~962 (1963)
- Felsby S, "NMDA receptor blockade in chronic neuropathic pain: a comparison of ketamine and magnesium chloride", Pain, 64, pp.283~291 (1996)
- Ko SH, "Magnesium sulfate does not reduce postoperative analgesic requirements", Anesthesiology, 95, pp.640~646 (2001)
- Saeki H, "Is intrathecal magnesium sulfate safe and protective against ischemic spinal cord injury in rabbits", Anesth Analg, 99, pp.1805~1812 (2004)
- Chanimov M, "Neurotoxicity after spinal anaesthesia induced by serial intrathecal injections of magnesium sulphate. An experimental study in a rat model", Anaesthesia, 52, pp.223~228 (1997)
- Bilir A, "Epidural magnesium reduces postoperative analgesic requirement", Br J Anaesth, 87, pp.519~523 (2007)
- Farouk S, "Pre-incisional epidural magnesium provides pre-emptive and preventive analgesia in patients undergoing abdominal hysterectomy", Br J Anaesth, 101, pp.694~699 (2008)
- Buvanendran A, "Intrathecal magnesium prolongs fentanyl analgesia: a prospective, randomized, controlled trial", Anesth Analg, 95, pp.661~666 (2002)
