Clinical effectiveness of combining platelet rich fibrin with alloplastic bone substitute for the management of combined endodontic periodontal lesion
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The term "endo-perio" lesion has been proposed to describe the destructivelesion resulting from inflammatory products found in varying degrees in both theperiodontium and the pulpal tissues. In most of the cases, clinical symptoms disappearfollowing successful endodontic therapy. However failure after conventional root canaltreatment calls for surgical intervention. A 35 year old male patient with endo-periolesion in right maxillary lateral incisor was treated with platelet rich fibrin (PRF) andalloplastic bone substitute after conventional endodontic therapy. At the end of 6months there was gain in clinical attachment, increased radiographic bone fill andreduction in probing depth which was maintained till 18 month follow-up. Presentcase report aims to evaluate the efficacy of PRF and alloplastic bone substitute inthe management of intrabony defect associated with endo-perio lesion in maxillarylateral incisor because the healing potential of PRF and bone graft has not beenwidely studied in endodontics. The use of PRF allows the clinician to optimize tissueremodelling, wound healing and angiogenesis by the local delivery of growth factorsand proteins. The novel technique described here enables the clinician to be benefitedfrom the full regenerative capacity of this autologous biologic material.
Abstract
The term "endo-perio" lesion has been proposed to describe the destructivelesion resulting from inflammatory products found in varying degrees in both theperiodontium and the pulpal tissues. In most of the cases, clinical symptoms disappearfollowing successful endodontic therapy. However failure after conventional root canaltreatment calls for surgical intervention. A 35 year old male patient with endo-periolesion in right maxillary lateral incisor was treated with platelet rich fibrin (PRF) andalloplastic bone substitute after conventional endodontic therapy. At the end of 6months there was gain in clinical attachment, increased radiographic bone fill andreduction in probing depth which was maintained till 18 month follow-up. Presentcase report aims to evaluate the efficacy of PRF and alloplastic bone substitute inthe management of intrabony defect associated with endo-perio lesion in maxillarylateral incisor because the healing potential of PRF and bone graft has not beenwidely studied in endodontics. The use of PRF allows the clinician to optimize tissueremodelling, wound healing and angiogenesis by the local delivery of growth factorsand proteins. The novel technique described here enables the clinician to be benefitedfrom the full regenerative capacity of this autologous biologic material.
참고문헌 (14)
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