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논문KCI 등재

화상 후 발생된 신경병증성 통증에서 Ketamine 근주에 의한 치료경험 증례 보고

Intramuscular Injection of Ketamine in the Treatment of Postburn Neuropathic Pain A case report

한태형|김현수|이수연|김광민|문성하|우철호
대한통증학회 (The Korean Pain Society)|2004.12|The Korean Journal of Pain|제17권 제2호|pp. 28-28

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Abstract

Abnormal return of cutaneous sensibility is common after burn injuries, with many patients complaining of neuropathic pain. Chronic neuropathic pain has been described in healed burns due to deficiencies in the reinnervation of the scar; abnormalities in newly regenerated nerve endings or possibly a more NMDA mediated central mechanism. Ketamine, a non-competitive NMDA receptor antagonist, has been used for analgesia in many cases of pain syndrome and it's routes of administration are variable. Blocking of the NMDA receptors abolishes the hypersensitivity in patients with neuropathic pain. Therefore, ketamine was tried in postburn neuropathic pain, with a similar antagonistic effect to that of a NMDA antagonist expected. A postburn neuropathic pain patient, who was successfully managed without any significant sign of side effects, using an intramuscular injection of ketamine, was experienced at our clinic.

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