Implant survival and risk factor analysis in regenerated bone: results from a 5-year retrospective study
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Purpose: The aims of this study were to evaluate the 5-year cumulative survival rate (CSR) of implants placed with guided bone regeneration (GBR) compared to implants placed in native bone, and to identify factors contributing to implant failure in regenerated bone. Methods: This retrospective cohort study included 240 patients who had implant placement either with a GBR procedure (regenerated bone group) or with pristine bone (native bone group). Data on demographic features (age, sex, smoking, and medical history), location of the implant, implant-specific features, and grafting procedures and materials were collected. The 5-year CSRs in both groups were estimated using Kaplan-Meier analysis. Risk factors for implant failure were analyzed with a Cox proportional hazards model. Results: In total, 264 implants in the native bone group and 133 implants in the regenerated bone group were analyzed. The 5-year CSRs were 96.4% in the regenerated bone group and 97.5% in the native bone group, which was not a significant difference. The multivariable analysis confirmed that bone status was not an independent risk factor for implant failure. However, smoking significantly increased the failure rate (hazard ratio, 10.7; P=0.002). Conclusions: The 5-year CSR of implants placed in regenerated bone using GBR was comparable to that of implants placed in native bone. Smoking significantly increased the risk of implant failure in both groups.
Abstract
Purpose: The aims of this study were to evaluate the 5-year cumulative survival rate (CSR) of implants placed with guided bone regeneration (GBR) compared to implants placed in native bone, and to identify factors contributing to implant failure in regenerated bone. Methods: This retrospective cohort study included 240 patients who had implant placement either with a GBR procedure (regenerated bone group) or with pristine bone (native bone group). Data on demographic features (age, sex, smoking, and medical history), location of the implant, implant-specific features, and grafting procedures and materials were collected. The 5-year CSRs in both groups were estimated using Kaplan-Meier analysis. Risk factors for implant failure were analyzed with a Cox proportional hazards model. Results: In total, 264 implants in the native bone group and 133 implants in the regenerated bone group were analyzed. The 5-year CSRs were 96.4% in the regenerated bone group and 97.5% in the native bone group, which was not a significant difference. The multivariable analysis confirmed that bone status was not an independent risk factor for implant failure. However, smoking significantly increased the failure rate (hazard ratio, 10.7; P=0.002). Conclusions: The 5-year CSR of implants placed in regenerated bone using GBR was comparable to that of implants placed in native bone. Smoking significantly increased the risk of implant failure in both groups.
참고문헌 (39)
- Aghaloo TL, "Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement", Int J Oral Maxillofac Implants, 22(Suppl), pp.49~70 (2007)
- Chiapasco M, "Augmentation procedures for the rehabilitation of deficient edentulous ridges with oral implants", Clin Oral Implants Res, 17(Suppl 2), pp.136~159 (2006)
- Nyman S, "Bone regeneration adjacent to titanium dental implants using guided tissue regeneration : a report of two cases", Int J Oral Maxillofac Implants, 5, pp.9~14 (1990)
- Benic GI, "Horizontal bone augmentation by means of guided bone regeneration", Periodontol 2000, 66, pp.13~40 (2014)
- Sanz-Sánchez I, "Effectiveness of lateral bone augmentation on the alveolar crest dimension : a systematic review and meta-analysis", J Dent Res, 94, pp.128S~142S (2015)
- Schenk RK, "Healing pattern of bone regeneration in membraneprotected defects : a histologic study in the canine mandible", Int J Oral Maxillofac Implants, 9, pp.13~29 (1994)
- Gher ME, "Bone grafting and guided bone regeneration for immediate dental implants in humans", J Periodontol, 65, pp.881~891 (1994)
- Dahlin C, "Treatment of fenestration and dehiscence bone defects around oral implants using the guided tissue regeneration technique : a prospective multicenter study", Int J Oral Maxillofac Implants, 10, pp.312~318 (1995)
- Buser D, "Surgical procedure in the mandible", Int J Periodontics Restorative Dent, 15, pp.10~29 (1995)
- Simion M, "Vertical ridge augmentation using a membrane technique associated with osseointegrated implants", Int J Periodontics Restorative Dent, 14, pp.496~511 (1994)
- Donos N, "Clinical outcomes of implants following lateral bone augmentation:systematic assessment of available options (barrier membranes, bone grafts, split osteotomy)", J Clin Periodontol, 35, pp.173~202 (2008)
- Chiapasco M, "Clinical outcomes of GBR procedures to correct peri-implant dehiscences and fenestrations : a systematic review", Clin Oral Implants Res, 20(Suppl 4), pp.113~123 (2009)
- Clementini M, "Success rate of dental implants inserted in horizontal and vertical guided bone regenerated areas : a systematic review", Int J Oral Maxillofac Surg, 41, pp.847~852 (2012)
- Milinkovic I, "Are there specific indications for the different alveolar bone augmentation procedures for implant placement? A systematic review", Int J Oral Maxillofac Surg, 43, pp.606~625 (2014)
- Rocchietta I, "Clinical outcomes of vertical bone augmentation to enable dental implant placement : a systematic review", J Clin Periodontol, 35, pp.203~215 (2008)
- Klinge B, "Tissue augmentation and esthetics (Working Group 3)", Clin Oral Implants Res, 20(Suppl 4), pp.166~170 (2009)
- Beretta M, "A restrospective evaluation of 192implants placed in augmented bone : long-term follow-up study", J Oral Implantol, 41, pp.669~674 (2015)
- Seibert JS, "Reconstruction of deformed, partially edentulous ridges, using full thickness onlay grafts. Part I. Technique and wound healing", Compend Contin Educ Dent, 4, pp.437~453 (1983)
- van Steenberghe D, "Naert I. Survival and success rates with oral endosseous implants", Proceedings of the 3rd European Workshop on Periodontology:Implant Dentistry, pp.242~254 (1999), Quintessence
- Kaplan EL, "Nonparametric estimation from incomplete observations", J Am Stat Assoc, 53, pp.457~481 (1958)
- Telleman G, "A systematic review of the prognosis of short(<10 mm)dental implants placed in the partially edentulous patient", J Clin Periodontol, 38, pp.667~676 (2011)
- Mezzomo LA, "Meta-analysis of single crowns supported by short(<10 mm)implants in the posterior region", J Clin Periodontol, 41, pp.191~213 (2014)
- Zitzmann NU, "Long-term results of implants treated with guided bone regeneration : a 5-year prospective study", Int J Oral Maxillofac Implants, 16, pp.355~366 (2001)
- Benić GI, "Clinical and radiographic comparison of implants in regenerated or native bone : 5-year results", Clin Oral Implants Res, 20, pp.507~513 (2009)
- Hämmerle CH, "A systematic review of the survival of implants in bone sites augmented with barrier membranes(guided bone regeneration)in partially edentulous patients", J Clin Periodontol, 29(Suppl 3), pp.226~231 (2002)
- Mayta-Tovalino F, "An 11-year retrospective research study of the predictive factors of peri-implantitis and implant failure : analytic-multicentric study of 1279 implants in Peru", Int J Dent, 2019, pp.3527872~ (2019)
- Sesma N, "Retrospective clinical study of 988 dual acid-etched implants placed in grafted and native bone for single-tooth replacement", Int J Oral Maxillofac Implants, 27, pp.1243~1248 (2012)
- Chuang SK, "Risk factors for dental implant failure : a strategy for the analysis of clustered failure-time observations", J Dent Res, 81, pp.572~577 (2002)
- Noda K, "A longitudinal retrospective study of the analysis of the risk factors of implant failure by the application of generalized estimating equations", J Prosthodont Res, 59, pp.178~184 (2015)
- Sánchez-Pérez A, "Tobacco as a risk factor for survival of dental implants", J Periodontol, 78, pp.351~359 (2007)
- Mesa F, "Multivariate study of factors influencing primary dental implant stability", Clin Oral Implants Res, 19, pp.196~200 (2008)
- 강대영, "Early implant failure: a retrospective analysis of contributing factors", Journal of Periodontal & Implant Science, 49(5), pp.287~298 (2019), 대한치주과학회[DOI]
- Chung DM, "Factors affecting late implant bone loss : a retrospective analysis", Int J Oral Maxillofac Implants, 22, pp.117~126 (2007)
- Strietzel FP, "Smoking interferes with the prognosis of dental implant treatment : a systematic review and meta-analysis", J Clin Periodontol, 34, pp.523~544 (2007)
- Tran DT, "Survival of dental Implants placed in grafted and nongrafted bone : a retrospective study in a university setting", Int J Oral Maxillofac Implants, 31, pp.310~317 (2016)
- Moy PK, "Dental implant failure rates and associated risk factors", Int J Oral Maxillofac Implants, 20, pp.569~577 (2005)
- Zinser MJ, "The predictors of implant failure after maxillary sinus floor augmentation and reconstruction : a retrospective study of 1045 consecutive implants", Oral Surg Oral Med Oral Pathol Oral Radiol, 115, pp.571~582 (2013)
- Al-Nawas B, "Augmentation procedures using bone substitute materials or autogenous bone-a systematic review and meta-analysis", Eur J Oral Implantology, 7(Suppl 2), pp.S219~S234 (2014)
- Machtei EE, "The effect of membrane exposure on the outcome of regenerative procedures in humans : a meta-analysis", J Periodontol, 72, pp.512~516 (2001)