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무기인산염이 골유도재생에 미치는 영향

Effect of inorganic polyphosphate on guided bone regeneration

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Abstract

This study was performed to evaluate the effect of inorganic polyphosphate on bone formation in the calvaria of rabbit in the procedure of guided bone regeneration with bovine cancellous bone graft and titanium reinforced expanded polytetrafluoroethylene(TR-ePTFE) membrane. The rabbits were divided into four groups. Control group I used only TR-ePTFE membrane, control group II used TR-ePTFE membrane and deproteinized bovine bone mineral soaked in saline, experimental group III and IV used TR-ePTFE membrane and deproteinized bovine bone mineral soaked in 1% or 2% inorganic polyphosphate respectively. After decortication in the calvaria, GBR procedure was performed on 12 rabbits with titanium reinforced ePTFE membrane filled with deproteinized bovine bone mineral soaked in saline or inorganic polyphosphate. The animals were sacrificed at 2 weeks, 4 weeks, and 8 weeks after the surgery. Decalcified and non-decalcified specimens were processed for histologic and immunohistochemistric analysis. 1. Titanium reinforced ePTFE(TR-ePTFE) membrane showed good spacemaking and cell occlusiveness capability, but it showed poor wound stabilization. 2. The deproteinized bovine bone mineral did not promote bone regeneration, but it acted as a space filler. 3. There was no complete resorption of the deproteinized bovine bone mineral within 8 weeks. 4. 1% inorganic polyphosphate did not promote bone formation, but 2% inorganic poly- phosphate promoted bone formation. Within the above results, 2% inorganic polyphosphate could be used effectively for bone regeneration.

참고문헌 (69)

  1. "Healing of bone defects by guided tissue regeneration", 81, pp.672~677 (1988)
  2. "Osteo- promotion for cranioplasty:An experimental study in rats using a membrane technique", 74, pp.487~497 (1991)
  3. "Bone augmentation at fenestrated implants by an osteopromotive membrane technique:A controlled clinical study", 2, pp.159~165 (1991)
  4. "Generation of new bone around titanium implants using a membrane technique:An experimental study in rabbits", 4, pp.19~25 (1989)
  5. "Healing of maxillary and mandibular bone defects using a membrane technique:An experimental study in monkeys", 24, pp.13~19 (1990)
  6. "The use of e-PTFE barrier membranes for bone promotion around titanium implants placed into extraction socket:A prospective multicenter study", 9, pp.31~40 (1994)
  7. "Localized ridge augmentation in dogs:A pilot study using membranes and hydroxyapatite", 61, pp.157~165 (1990)
  8. "Bone formation at dehisced dental implant sites treated with implant augmentation material:A pilot study in dogs", 10, pp.93~101 (1990)
  9. "Guided tissue regeneration of dental implants placed into extraction sockets:An experimental study in monkeys", 2, pp.166~171 (1991)
  10. "Bone regeneration around titanium implants in dehisced defect sites:A clinical study", 7, pp.233~245 (1992)
  11. "Guided tissue regeneration for implant placed into extraction sockets:A study in dogs", 62, pp.703~709 (1991)
  12. "Immediate transmucosal implants using the principle of guided tissue regeneration II:A cross-sectional study comparing the clinical outcome 1 year after immediate to standard implant placement", 7, pp.268~276 (1997)
  13. "Regeneration and enlargement of jaw bone using guided tissue regeneration", 1, pp.22~32 (1990)
  14. "Treatment of fenestration and dehiscence bone defects around oral implants using the guided tissue regenera- tion technique:A prospective multicenter study", 10, pp.312~318 (1995)
  15. "The biological effect of deproteinized bovine bone on bone neoformation on the rabbit skull", 8, pp.198~207 (1997)
  16. "Guided tissue regeneration in jaw bone defects prior to implant placement", 5, pp.92~97 (1994)
  17. "Augmentation of the rat jaw with autogenic cortico-cancellous bone grafts and guided tissue regeneration", 13, pp.192~202 (2002)
  18. "Augmentation of the mandible with GTR and onlay cortical bone grafting.An experimental study in the rat", 13, pp.175~184 (2002)
  19. "Lateral ridge augmentation using different bone fillers and barrier membrane application.A histologic and histomorphometric pilot study in the mandible", 12, pp.260~269 (2001)
  20. "Enhancement of the damaged edentulous ridge to receive dental implants a combination of allograft and the GORE- TEX", 12, pp.97~111 (1992)
  21. "Vertical ridge augmentation using a membrane technique associated with osseointegrated implants", 14, pp.496~511 (1994)
  22. "Supracrestal bone formation around dental implants:an experimen- tal dog study", 10, pp.23~31 (1995)
  23. "Bone formation utilizing titanium-reinforced barrier membranes", 15, pp.57~69 (1995)
  24. "The role of early versus late removal of GRAM membrane on bone formation at oral implants placed into immediate extraction sockets.An experimental study in dogs", 4, pp.121~129 (1993)
  25. "Alveolar ridge augmentation by combining autogenous mandibular bone grafts and nonresorbable membranes.An experimental study in the rat", 13, pp.185~191 (2002)
  26. "Rigid fixation by means of titanium mesh in edentulous ridge expansion for horizontal ridge augmentation in the maxilla", 13, pp.701~705 (1998)
  27. "Augmentation of calvarial tissue using non-permeable silicone domes and bovine bone mineral.An experimental study in the rat", 10, pp.468~476 (1999)
  28. "Comparison of bone regenera- tion with the use of mineralized and demineralized freezedried bone allografts:a histologic and histochemical study in man", 17, pp.1127~1131 (1996)
  29. "Implants in regenerated bone:long-term survival", 18, pp.35~45 (1998)
  30. "Freeze-dried bone for maxillary sinus augmentation in sheep", 13, pp.581~586 (2002)
  31. "Clinical and histologic evaluation of bone- replacement grafts in the treatment of localized alveolar ridge defects", 23, pp.29~35 (2003)
  32. "탈회동결건조골과 합성골이식재가 치조골 결손부 재생과정에 미치는 영향", 24, pp.671~684 (1994)
  33. "Bone grafting material for dental application:A practical guide", 18, pp.1013~1036 (1997)
  34. "Augmentation of calvarial tissue using non-permeable silicone domes and bovine bone mineral.An experimental study in the rat", 10, pp.468~476 (1999)
  35. "Analysis of the size of the specific surface area of bone regeneration materials by gas adsorption", g(th sh), pp.1~5 (2000)
  36. "Bone apposition onto oral implants in the sinus area filled with different grafting materials", 6, pp.155~163 (1995)
  37. "Bone reactions to anorganic bovine bone used in sinus augmentation procedure A histologic long term of 20 cases in humans", pp.835~840 (1999)
  38. "Osseous response to implanted natural bone mineral and synthetic hydroxyapatite ceramic in the repair of experimental skull bone defects", 50, pp.241~249 (1992)
  39. "Maxillary sinus augmentation using different grafting materials and dental implants in monkeys Evaluation of anorganic bovine-derived bone matrix", pp.476~486 (1997)
  40. "Healing around implants placed in bone defects treated with Bio-Oss.An experimental study in the dog", 8, pp.117~124 (1997)
  41. "Orthodontic movement in bone defects augmented with Bio-Oss.An experimental study in dogs", 28, pp.73~80 (2001)
  42. "The effect of a fibrin glue on the integration of Bio-Oss An experimental study in labrador dogs", carmag(la d), pp.377~383 (2002)
  43. "Healing of human extraction sockets filled with Bio-Oss", 14, pp.137~143 (2003)
  44. "arrest bone formation when used as an adjunct to guided tissue regenera- tion An experimental study in the rat", pp.636~643, Nyen- gaard
  45. "Augmentation of calvarial tissue using non-permeable silicone domes and bovine bone mineral.An experimental study in the rat", 10, pp.468~476 (1999)
  46. "Growth factors for bone growth and repair", pp.1~12 (1996)
  47. "Transforming growth factor beta in fracture repair", pp.124~131 (1998)
  48. "Final report on the safety assessment of sodium metaphosphate", pp.75~89
  49. "The United States Department of Agri- culture"
  50. "Inorganic polyphosphate:toward making a forgotten polymer un- forgettable", 177, pp.491~496 (1995)
  51. "Evidence for the occurrence and distribution of inorganic polyphosphate in vertebrae tissues", 18, pp.1229~1242 (1971)
  52. "Inorganic polyphosphate in mammalian cells and ti- ssues", 270, pp.5818~5822 (1995)
  53. "Mechanisms of action of the bisphosphonates", pp.65~75 (1997)
  54. "Inorganic polyphosphate in human osteoblast-like cells", 13, pp.803~812 (1998)
  55. "Modulation of mitogenic activity of fibroblast growth factors by inorganic polyphosphate", 278, pp.26788~26792 (2003)
  56. "Healing pattern of bone regeneration in membrane-protected defects.A histologic study in the canine mandible", 9, pp.13~29 (1994)
  57. "골유도재생술시 그물형 티타늄막의 천공수가 골형성에 미치는 영향", 34, pp.411~424 (2004)
  58. "Role of intramarrow penetration in osseous repair:A pilot study in the rabbit calvaria", 70, pp.1501~1510 (1999)
  59. "Augmentation of intramem- branous bone beyond the skeletal envelope using an occlusive titanium barrier", 6, pp.67~72 (1995)
  60. "Vertical ridge augmentation: what is the limit?", pp.220~229 (1996)
  61. "Expanded polytetrafluoroethylene titanium-reinforced membrane for regeneration of mucogingival recession defects:A 12-cases report", 65, pp.1088~1094 (1994)
  62. "골유도재생술시 탈단백우골이 세포증식에 미치는 영향", 34, pp.683~698 (2004)
  63. "Growth factors in bone", 22, pp.410~416 (1998)
  64. "Bone morphogenetic proteins:an update on basic biology and clinical rel- evance", 17, pp.269~278 (1999)
  65. "Stimulation of fracture healing by local application of humoral factors integrated in biodegradable implants", 8, pp.251~255 (1998)
  66. "Induction of calcification in MC3T3-E1 cells by inorganic polyphosphate", 83, pp.613~618 (2004)
  67. "무기인산염의 골재생 촉진효과에 관한 연구", 23, pp.219~228 (1999)
  68. "Initiation of fracture repair by bone morphogenetic proteins", pp.66~72
  69. "Initiation of fracture repair by bone morphogenetic proteins", pp.66~72

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