Palliative Sedation in End-of-Life Patients in Eastern Asia: A Narrative Review
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Although palliative sedation (PS) is a common practice in the palliative care of cancer patients in Western countries, there is little related research on the practice in Korea. PS can be classified into several categories according to sedation level and continuity. PS is clearly distinct from euthanasia. While euthanasia is illegal and regarded as unethical in Korea, there is little ethical and legal controversy about PS in terms of the doctrine of double effect. Most studies have asserted that PS does not shorten the survival of terminal cancer patients. Since preference for PS heavily depends on stakeholder value, it should be preceded by shared decision-making through full communication among the patient, family members, and medical team. This is a narrative review article analyzing previous studies, especially from the three Eastern Asian countries, Korea, Japan and Taiwan, which share similar cultures compared with Western countries. Practical issues concerning PS—for example, prevalence, type and dosage of medications, salvage medication, timing of its initiation, and assessment—are described in detail.
Abstract
Although palliative sedation (PS) is a common practice in the palliative care of cancer patients in Western countries, there is little related research on the practice in Korea. PS can be classified into several categories according to sedation level and continuity. PS is clearly distinct from euthanasia. While euthanasia is illegal and regarded as unethical in Korea, there is little ethical and legal controversy about PS in terms of the doctrine of double effect. Most studies have asserted that PS does not shorten the survival of terminal cancer patients. Since preference for PS heavily depends on stakeholder value, it should be preceded by shared decision-making through full communication among the patient, family members, and medical team. This is a narrative review article analyzing previous studies, especially from the three Eastern Asian countries, Korea, Japan and Taiwan, which share similar cultures compared with Western countries. Practical issues concerning PS—for example, prevalence, type and dosage of medications, salvage medication, timing of its initiation, and assessment—are described in detail.
참고문헌 (39)
- Teunissen SC, "Symptom prevalence in patients with incurable cancer : a systematic review", J Pain Symptom Manage, 34, pp.94~104 (2007)
- Maltoni M, "Palliative sedation in patients with cancer", Cancer Control, 22, pp.433~441 (2015)
- Gurschick L, "Palliative sedation : an analysis of International Guidelines and Position Statements", Am J Hosp Palliat Care, 32, pp.660~671 (2015)
- Korean Society of Critical Care Medicine, "Korean professional consensus for comfort care and withdrawing", withholding in the intensive care unit, 2019
- National Cancer Center, "Cancer pain management guideline" (2019), National Cancer Center
- 신진영, "Clinical Practice Guideline for Care in the Last Days of Life", Journal of Hospice and Palliative Care, 23(3), pp.103~113 (2020), 한국호스피스완화의료학회[DOI]
- Jackson WC, "Palliative sedation vs. terminal sedation: what’s in a name?", Am J Hosp Palliat Care, 19, pp.81~82 (2002)
- Twycross R, "Reflections on palliative sedation", Palliat Care, 12, pp.1178224218823511~ (2019)
- Lipuma SH, "Continuous sedation until death as physician-assisted suicide", euthanasia : a conceptual analysis, 2013, pp.38, 190~204
- Sheldon T, ""Terminal sedation"different from euthanasia, Dutch ministers agree", BMJ, 327, pp.465~ (2003)
- Kendall CE, "At the coalface : medical ethics in practice : a double dose of double effect", J Med Ethics, 26, pp.204~205 (2000)
- Maeda I, "Effect of continuous deep sedation on survival in patients with advanced cancer(J-Proval) : a propensity score-weighted analysis of a prospective cohort study", Lancet Oncol, 17, pp.115~122 (2016)
- Yokomichi N, "Effect of continuous deep sedation on survival in the last days of life of cancer patients : a multicenter prospective cohort study", Palliat Med, 36, pp.189~199 (2022)
- Schur S, "Sedation at the end of life : a nation-wide study in palliative care units in Austria", BMC Palliat Care, 15, pp.50~ (2016)
- Morita T, "Similarity and difference among standard medical care, palliative sedation therapy, and euthanasia : a multidimensional scaling analysis on physicians’ and the general population’s opinions", J Pain Symptom Manage, 25, pp.357~362 (2003)
- 한지희, "수정된 한글 연명의료계획서(Modified Korean Physician Order for Life-Sustaining Treatment, MK-POLST) 분석을 통한 호스피스 병동 환자의 의료 중재 항목별 선호도 및 충실도 조사", Journal of Hospice and Palliative Care, 22(4), pp.198~206 (2019), 한국호스피스완화의료학회[DOI]
- Morita T, "Concerns of family members of patients recei-ving palliative sedation therapy", Support Care Cancer, 12, pp.885~889 (2004)
- Shen HS, "Differential family experience of palliative sedation therapy in specialized palliative or critical care units", J Pain Symptom Manage, 55, pp.1531~1539 (2018)
- Morita T, "Family experience with palliative sedation the-rapy for terminally ill cancer patients", J Pain Symptom Manage, 28, pp.557~565 (2004)
- Eun Y, "Qualitative study on the perceptions of terminally ill cancer patients and their family members regarding end-of-life experiences focusing on palliative sedation", J Pain Symptom Manage, 53, pp.1010~1016 (2017)
- Belar A, "The decision-making process for palliative sedation for patients with advanced cancer-analysis from a systematic review of prospective studies", Cancers(Basel), 14, pp.301~ (2022)
- Morita T, "Palliative care physicians’ attitudes toward patient autonomy and a good death in East Asian countries", J Pain Symptom Manage, 50, pp.190~199 (2015)
- Yamaguchi T, "Communication and behavior of palliative care physicians of patients with cancer near end of life in three East Asian countries", J Pain Symptom Manage, 61, pp.315~322 (2021)
- Caraceni A, "Palliative sedation in terminal cancer patients admitted to hospice or home care programs : does the setting matter? Results from a national multicenter observational study", J Pain Symptom Manage, 56, pp.33~43 (2018)
- Kim YS, "Sedation for terminally ill cancer patients : a multicenter retrospective cohort study in South Korea", Medicine(Baltimore), 98, pp.e14278~ (2019)
- Won YW, "Clinical patterns of continuous and intermittent palliative sedation in patients with terminal cancer : a descriptive, observational study", J Pain Symptom Manage, 58, pp.65~71 (2019)
- van Deijck RH, "The practice of continuous palliative sedation in long-term care for frail patients with existential suffering", J Palliat Care, 31, pp.141~149 (2015)
- Rodrigues P, "Palliative sedation for existential suffering : a systematic review of argument-based ethics literature", J Pain Symptom Manage, 55, pp.1577~1590 (2018)
- Elwyn G, "A three-talk model for shared decision making : multistage consultation process", BMJ, 359, pp.j4891~ (2017)
- Bodnar J, "A review of agents for palliative sedation", continuous deep sedation : pharmacology and practical applications, 2017, pp.31, 16~37
- Morita T, "Efficacy and safety of palliative sedation therapy : a multicenter, prospective, observational study conducted on specialized palliative care units in Japan", J Pain Symptom Manage, 30, pp.320~328 (2005)
- Hui D, "Neuroleptics in the management of delirium in patients with advanced cancer", Curr Opin Support Palliat Care, 10, pp.316~323 (2016)
- Hui D, "Effect of lorazepam with haloperidol vs haloperidol alone on agitated delirium in patients with advanced cancer receiving palliative care : a randomized clinical trial", JAMA, 318, pp.1047~1056 (2017)
- Fredheim OM, "Clinical and ethical aspects of palliative sedation with propofol : a retrospective quantitative and qualitative study", Acta Anaesthesiol Scand, 64, pp.1319~1326 (2020)
- Setla J, "Home palliative sedation using phenobarbital suppositories : time to death, patient characteristics, and administration protocol", Am J Hosp Palliat Care, 36, pp.871~876 (2019)
- Belar A, "How to measure the effects and potential adverse events of palliative sedation? An integrative review", Palliat Med, 35, pp.295~314 (2021)
- Bruinsma S, "Palliative sedation : a focus group study on the experiences of relatives", J Palliat Med, 16, pp.349~355 (2013)
- Swart SJ, "Physicians’ and nurses’ experiences with continuous palliative sedation in the Netherlands", Arch Intern Med, 170, pp.1271~1274 (2010)
- Schildmann EK, "Medication and monitoring in palliative sedation therapy : a systematic review and quality assessment of published guidelines", J Pain Symptom Manage, 49, pp.734~746 (2015)
