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Descriptive Analysis of Gastric Cancer Mortality in Korea, 2000-2020

신애선|이지유|조수영|Tung Hoang|우형택|Sayada Zartasha Kazmi
대한암학회 (Korean Cancer Association)|2023.04|Cancer Research and Treatment|제55권 제2호|pp. 603-617|DOI 10.4143/crt.2022.307

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키워드

KoreaSpatial analysisAge-period-cohort analysisJoinpoint regressionGastric cancer mortality
주제분류의학일반

초록

Purpose This study aimed to examine secular trends, age-period-cohort effects, and geographical differences in gastric cancer (GC) mortality in Korea. Materials and Methods Using cause of death data from the Korean Statistical Information Service for GC from 2000 to 2020, we calculated average annual percentage changes (AAPCs) in the age-standardized mortality of GC in 17 cities and provinces through joinpoint regression. Decomposition of age, period, and cohort effects on GC mortality were elucidated by applying a log-linear model and an intrinsic estimate method. Spatial patterns and the degree of spatial clustering in 250 administrative regions were explored via Moran’s I statistics. Stratification by sex was performed for all analyses. Results The age-standardized mortality of GC per 100,000 persons declined from 29.0 in 2000 to 7.9 in 2020 (AAPC, –6.28%). Age-period-cohort analyses of GC mortality showed a downward trend among 5-year age groups from age 20-89 years across five-year periods from 2005-2020 and 5-year birth cohorts from 1920 to 2000. Overall, the younger birth cohort showed lower mortality rates than the older cohort within the same period. In 2020, clusters of high GC mortality were observed in the central area for men (Chungcheongbuk-do, Jeollabuk-do, Gyeongsangbuk-do, and Gyeongsangnam-do) and in the eastern area for women (Gyeongsangbuk-do). Conclusion This study identified a downward trend in GC mortality among men and women from 2000 to 2020 in Korea. This trend was mainly attributed to birth cohort rather than period effects. Spatial analysis showed high GC mortality in the Chungcheong-do and Gyeongsangbuk-do areas.

Abstract

Purpose This study aimed to examine secular trends, age-period-cohort effects, and geographical differences in gastric cancer (GC) mortality in Korea. Materials and Methods Using cause of death data from the Korean Statistical Information Service for GC from 2000 to 2020, we calculated average annual percentage changes (AAPCs) in the age-standardized mortality of GC in 17 cities and provinces through joinpoint regression. Decomposition of age, period, and cohort effects on GC mortality were elucidated by applying a log-linear model and an intrinsic estimate method. Spatial patterns and the degree of spatial clustering in 250 administrative regions were explored via Moran’s I statistics. Stratification by sex was performed for all analyses. Results The age-standardized mortality of GC per 100,000 persons declined from 29.0 in 2000 to 7.9 in 2020 (AAPC, –6.28%). Age-period-cohort analyses of GC mortality showed a downward trend among 5-year age groups from age 20-89 years across five-year periods from 2005-2020 and 5-year birth cohorts from 1920 to 2000. Overall, the younger birth cohort showed lower mortality rates than the older cohort within the same period. In 2020, clusters of high GC mortality were observed in the central area for men (Chungcheongbuk-do, Jeollabuk-do, Gyeongsangbuk-do, and Gyeongsangnam-do) and in the eastern area for women (Gyeongsangbuk-do). Conclusion This study identified a downward trend in GC mortality among men and women from 2000 to 2020 in Korea. This trend was mainly attributed to birth cohort rather than period effects. Spatial analysis showed high GC mortality in the Chungcheong-do and Gyeongsangbuk-do areas.

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관련 논문AI추천

Trends in Gastric Cancer Incidence According to the Clinicopathological Characteristics in Korea, 1999-2014김영우, 양한나, 엄방울, 원영주, 정규원대한암학회 · Cancer Research and Treatment2018 · 제50권 제4호Age-Period-Cohort Analysis of Female Breast Cancer Mortality in Korea김연주, 박수경, 신혜림, 유근영, 최윤희대한암학회 · Cancer Research and Treatment2016 · 제48권 제1호Regional disparities in major cancer incidence in Korea, 1999-2018서홍관, Choi Chang Kyun, Jeong-Soo Im, Jung Kyu-Won, Kang Mee Joo, Kim Hye-Jin, Kong Hyun-Joo, Park Eun Hye, Yun E Hwa한국역학회 · Epidemiology and Health2023 · 제45권 Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2020강미주, 공현주, 김혜진, 박은혜, 방소현, 서홍관, 윤이화, 임정수, 정규원, 최서현, The Community of Population-Based Regional Cancer Registries대한암학회 · Cancer Research and Treatment2023 · 제55권 제2호Long Term Trends and the Future Gastric Cancer Mortality in Korea: 1983～2013유근영, Jae-Kwan Jun, Jin Gwack, Jisuk Bae, Kwang-Pil Ko, Yeonju Kim, Yunhee Choi대한암학회 · Cancer Research and Treatment2006 · 제38권 제1호Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2018공현주, 서홍관, 원영주, 이재준, 임정수, 정규원, 홍세리, The Community of Population-Based Regional Cancer Registries대한암학회 · Cancer Research and Treatment2021 · 제53권 제2호

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