Clinical case report on treatment of generalized aggressive periodontitis
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
periodontitis (GAgP) diagnosed patients treated with non-surgical periodontal therapy accompanying systemic antibiotics administration. Methods: Two patients with GAgP were chosen for this study. Clinical indices were taken and a radiographic examination was performed at the baseline of the study and they were treated by periodontal therapy accompanying systemic antibiotics administration. Post-surgical visits were scheduled at regular intervals to check clinical and radiographic changes. Results: Through non-surgical periodontal therapy accompanying systemic antibiotics administration, GAgP patients showed decreased probing pocket depth, sulcus bleeding index, and increased attachment level and clinical index when comparing the initial and six month follow up data. In the six month follow-up radiographic examination after non-surgical periodontal therapy, resolution of the bony defect was observed. Conclusions: Non-surgical therapy combined with systemic antibiotics administration in GAgP patients is suggested to be an effective approach to enhance the periodontal health.
Abstract
periodontitis (GAgP) diagnosed patients treated with non-surgical periodontal therapy accompanying systemic antibiotics administration. Methods: Two patients with GAgP were chosen for this study. Clinical indices were taken and a radiographic examination was performed at the baseline of the study and they were treated by periodontal therapy accompanying systemic antibiotics administration. Post-surgical visits were scheduled at regular intervals to check clinical and radiographic changes. Results: Through non-surgical periodontal therapy accompanying systemic antibiotics administration, GAgP patients showed decreased probing pocket depth, sulcus bleeding index, and increased attachment level and clinical index when comparing the initial and six month follow up data. In the six month follow-up radiographic examination after non-surgical periodontal therapy, resolution of the bony defect was observed. Conclusions: Non-surgical therapy combined with systemic antibiotics administration in GAgP patients is suggested to be an effective approach to enhance the periodontal health.
참고문헌 (29)
- American Academy of Periodontology, "Parameter on aggressive periodontitis", J Periodontol, 71(5 Suppl), pp.867~869 (2000)
- Tonetti MS, "Early-onset periodontitis", Ann Periodontol, 4, pp.39~53 (1999)
- Guerrero A, "Adjunctive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: a randomized placebo-controlled clinical trial", J Clin Periodontol, 32, pp.1096~1107 (2005)
- Pavicic MJ, "Microbiological and clinical effects of metronidazole and amoxicillin in Actinobacillus actinomycetemcomitans-associated periodontitis. A 2-year evaluation", J Clin Periodontol, 21, pp.107~112 (1994)
- Fine DH, "Aggregatibacter actinomycetemcomitans and its relationship to initiation of localized aggressive periodontitis: longitudinal cohort study of initially healthy adolescents", J Clin Microbiol, 45, pp.3859~3869 (2007)
- Haraszthy VI, "Evidence for the role of highly leukotoxic Actinobacillus actinomycetemcomitans in the pathogenesis of localized juvenile and other forms of early-onset periodontitis", J Periodontol, 71, pp.912~922 (2000)
- DiRienzo JM, "Specific genetic variants of Actinobacillus actinomycetemcomitans correlate with disease and health in a regional population of families with localized juvenile periodontitis", Infect Immun, 62, pp.3058~3065 (1994)
- Page RC, "Abnormal leukocyte motility in patients with early-onset periodontitis", J Periodontal Res, 19, pp.591~594 (1984)
- Lavine WS, "Impaired neutrophil chemotaxis in patients with juvenile and rapidly progressing periodontitis", J Periodontal Res, 14, pp.10~19 (1979)
- Page RC, "Defective neutrophil and monocyte motility in patients with early onset periodontitis", Infect Immun, 47, pp.169~175 (1985)
- Hart TC, "Genetic factors in the pathogenesis of periodontitis", Periodontol 2000, 14, pp.202~215 (1997)
- Kinane DF, "The genetic basis of periodontitis", Periodontol 2000, 39, pp.91~117 (2005)
- Boughman JA, "Phenotypic assessment of early onset periodontitis in sibships", J Clin Periodontol, 19, pp.233~239 (1992)
- Beaty TH, "Genetic analysis of juvenile periodontitis in families ascertained through an affected proband", Am J Hum Genet, 40, pp.443~452 (1987)
- Saxen L, "Autosomal recessive inheritance of juvenile periodontitis: test of a hypothesis", Clin Genet, 25, pp.332~335 (1984)
- Hart TC, "Re-interpretation of the evidence for X-linked dominant inheri tance of juvenile periodontitis", J Periodontol, 63, pp.169~173 (1992)
- Melnick M, "Periodontosis: a phenotypic and genetic analysis", Oral Surg Oral Med Oral Pathol, 42, pp.32~41 (1976)
- Page RC, "Clinical and laboratory studies of a family with a high prevalence of juvenile periodontitis", J Periodontol, 56, pp.602~610 (1985)
- Buchmann R, "Aggressive periodontitis: 5-year follow-up of treatment", J Periodontol, 73, pp.675~683 (2002)
- Berglundh T, "The use of metronidazole and amoxicillin in the treatment of advanced periodontal disease. A prospective,controlled clinical trial", J Clin Periodontol, 25, pp.354~362 (1998)
- Winkel EG, "Additional clinical and microbiological effects of amoxicillin and metronidazole after initial periodontal therapy", J Clin Periodontol, 25, pp.857~864 (1998)
- Sigusch B, "A 2-step non-surgical procedure and systemic antibiotics in the treatment of rapidly progressive periodontitis", J Periodontol, 72, pp.275~283 (2001)
- Renvert S, "5-year follow up of periodontal intraosseous defects treated by root planing or flap surgery", J Clin Periodontol, 17, pp.356~363 (1990)
- Worch KP, "A multidisciplinary approach to the diagnosis and treatment of earlyonset periodontitis: a case report", J Periodontol, 72, pp.96~106 (2001)
- Passanezi E, "Interdisciplinary treatment of localized juvenile periodontitis: a new perspective to an old problem", Am J Orthod Dentofacial Orthop, 131, pp.268~276 (2007)
- Kamma JJ, "Five-year maintenance follow-up of early-onset periodontitis patients", J Clin Periodontol, 30, pp.562~572 (2003)
- van Winkelhoff AJ, "Microbiological and clinical results of metronidazole plus amoxicillin therapy in Actinobacillus actinomycetemcomitans-associated periodontitis", J Periodontol, 63, pp.52~57 (1992)
- Heitz-Mayfield L, "Microbial colonization patterns predict the outcomes of surgical treatment of intrabony defects", J Clin Periodontol, 33, pp.62~68 (2006)
- Cortellini P, "Periodontal regeneration of human infrabony defects (V). Effect of oral hygiene on long-term stability", J Clin Periodontol, 21, pp.606~610 (1994)