본문 바로가기
KERD
논문KCI 등재

Biologic response of local hemostatic agents used in endodontic microsurgery

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류치의학

초록

Appropriate use of local hemostatic agent is one of the important factors on the prognosis of endodontic microsurgery. However, most investigations to date focus on the hemostatic efficacy of the agents, whereas their biologic characteristics have not received enough attention. The purpose of this paper was to review the biologic response of local hemostatic agents, and to provide clinical guidelines on their use during endodontic microsurgery. Electronic database (PUBMED) was screened to search related studies from 1980 to 2013, and 8 clinical studies and 18 animal studies were identified. Among the materials used in these studies, most widely-investigated and used materials, epinephrine, ferric sulfate (FS) and calcium sulfate (CS), were thoroughly discussed. Influence of these materials on local tissue and systemic condition, such as inflammatory and foreign body reaction, local ischemia, dyspigmentation, delayed or enhanced bone and soft tissue healing, and potential cardiovascular complications were assessed. Additionally, biological property of their carrier materials, cotton pellet and absorbable collagen, were also discussed. Clinicians should be aware of the biologic properties of local hemostatic agents and their carrier materials, and should pay attention to the potential complications when using them in endodontic microsurgery.

Abstract

Appropriate use of local hemostatic agent is one of the important factors on the prognosis of endodontic microsurgery. However, most investigations to date focus on the hemostatic efficacy of the agents, whereas their biologic characteristics have not received enough attention. The purpose of this paper was to review the biologic response of local hemostatic agents, and to provide clinical guidelines on their use during endodontic microsurgery. Electronic database (PUBMED) was screened to search related studies from 1980 to 2013, and 8 clinical studies and 18 animal studies were identified. Among the materials used in these studies, most widely-investigated and used materials, epinephrine, ferric sulfate (FS) and calcium sulfate (CS), were thoroughly discussed. Influence of these materials on local tissue and systemic condition, such as inflammatory and foreign body reaction, local ischemia, dyspigmentation, delayed or enhanced bone and soft tissue healing, and potential cardiovascular complications were assessed. Additionally, biological property of their carrier materials, cotton pellet and absorbable collagen, were also discussed. Clinicians should be aware of the biologic properties of local hemostatic agents and their carrier materials, and should pay attention to the potential complications when using them in endodontic microsurgery.

참고문헌 (82)

  1. Kim S, "Hemostasis in endodontic microsurgery", Dent Clin North Am, 41, pp.499~511 (1997)
  2. Witherspoon DE, "Haemostasis in periradicular surgery", Int Endod J, 29, pp.135~149 (1996)
  3. 조용욱, "Is stopping of anticoagulant therapy really required in a minor dental surgery? - How about in an endodontic microsurgery?", Restorative Dentistry and Endodontics, 38(3), pp.113~118 (2013), 대한치과보존학회[DOI]
  4. Finn MD, "Osseous regeneration in the presence of four common hemostatic agents", J Oral Maxillofac Surg, 50, pp.608~612 (1992)
  5. Ibarrola JL, "Osseous reactions to three hemostatic agents", J Endod, 11, pp.75~83 (1985)
  6. Johnson P, "Effects of bone wax on bacterial clearance", Surgery, 89, pp.206~209 (1981)
  7. Papay FA, "Comparison of ossification of demineralized bone, hydroxyapatite, Gelfoam, and bone wax in cranial defect repair", J Craniofac Surg, 7, pp.347~351 (1996)
  8. Thaller SR, "Calvarial bone graft donor site: a histological study in a rabbit model.", Ann Plast Surg, 23, pp.390~395 (1989)
  9. Nappi JF, "The effects of Surgicel on bone formation", Cleft Palate J, 17, pp.291~296 (1980)
  10. Alkan A, "The effects of hemostatic agents on peripheral nerve function: an experimental study", J Oral Maxillofac Surg, 65, pp.630~634 (2007)
  11. Boyes-Varley JG, "Effect of a topical drug combination on the early healing of extraction sockets in the vervet monkey", Int J Oral Maxillofac Surg, 17, pp.138~141 (1988)
  12. Hjortdal O., "The fate of resorbable hemostatic implants in rats", Acta Odontol Scand, 28, pp.323~336 (1970)
  13. De Leonardis D, "Augmentation of the maxillary sinus with calcium sulfate: one-year clinical report from a prospective longitudinal study", Int J Oral Maxillofac Implants, 14, pp.869~878 (1999)
  14. Pecora G, "The use of calcium sulphate in the surgical treatment of a ‘through and through’ periradicular lesion", Int Endod J, 34, pp.189~197 (2001)
  15. Vickers FJ, "Hemostatic efficacy and cardiovascular effects of agents used during endodontic surgery", J Endod, 28, pp.322~323 (2002)
  16. Vy CH, "Cardiovascular effects and efficacy of a hemostatic agent in periradicular surgery", J Endod, 30, pp.379~383 (2004)
  17. Csillag M, "Dose-related effects of epinephrine on human gingival blood flow and crevicular fluid production used as a soaking solution for chemo-mechanical tissue retraction", J Prosthet Dent, 97, pp.6~11 (2007)
  18. Scarano A, "Application of calcium sulfate in surgical-orthodontic treatment of impacted teeth: a new procedure to control hemostasis", J Oral Maxillofac Surg, 68, pp.964~968 (2010)
  19. Scarano A, "Hemostasis control in endodontic surgery: a comparative study of calcium sulfate versus gauzes and versus ferric sulfate", J Endod, 38, pp.20~23 (2012)
  20. Lemon RR, "Ferric sulfate hemostasis: effect on osseous wound healing. Left in situ for maximum exposure", J Endod, 19, pp.170~173 (1993)
  21. Jeansonne BG, "Ferric sulfate hemostasis: effect on osseous wound healing. II. With curettage and irrigation", J Endod, 19, pp.174~176 (1993)
  22. Pecora G, "Bone regeneration with a calcium sulfate barrier", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 84, pp.424~429 (1997)
  23. Clokie CM, "Closure of critical sized defects with allogenic and alloplastic bone substitutes", J Craniofac Surg, 13, pp.111~121 (2002)
  24. Miller Q, "The effect of topical epinephrine on peripheral nerve conduction", Laryngoscope, 112, pp.1888~1891 (2002)
  25. Murashima Y, "Calcium sulphate as a bone substitute for various osseous defects in conjunction with apicectomy", Int Endod J, 35, pp.768~774 (2002)
  26. Strocchi R, "Bone regeneration with calcium sulfate: evidence for increased angiogenesis in rabbits", J Oral Implantol, 28, pp.273~278 (2002)
  27. Walsh WR, "Response of a calcium sulfate bone graft substitute in a confined cancellous defect", Clin Orthop Relat Res, 406, pp.228~236 (2003)
  28. Apaydin ES, "Torabinejad M. The effect of calcium sulfate on hard-tissue healing after periradicular surgery", J Endod, 30, pp.17~20 (2004)
  29. Orsini G, "Bone-defect healing with calcium-sulfate particles and cement: an experimental study in rabbit", J Biomed Mater Res B Appl Biomater, 68, pp.199~208 (2004)
  30. von Arx T, "Haemostatic agents used in periradicular surgery: an experimental study of their efficacy and tissue reactions", Int Endod J, 39, pp.800~808 (2006)
  31. Jensen SS, "Haemostatic effect and tissue reactions of methods and agents used for haemorrhage control in apical surgery", Int Endod J, 43, pp.57~63 (2010)
  32. Azargoon H, "Assessment of hemostatic efficacy and osseous wound healing using HemCon dental dressing", J Endod, 37, pp.807~811 (2011)
  33. Katzung BG, "Basic and clinical pharmacology", pp.129~149 (2011), McGraw-Hill Education
  34. Kim S, "Modern endodontic surgery concepts and practice: a review", J Endod, 32, pp.601~623 (2006)
  35. 추완식, "기계적으로 자극 받은 치아에서 국소마취가 치수혈류에 미치는 영향", Restorative Dentistry and Endodontics, 31(4), pp.257~262 (2006), 대한치과보존학회
  36. 이재상, "국소마취제에 함유된 에피네프린의 농도가 치수 및 치은 혈류에 미치는 영향", Restorative Dentistry and Endodontics, 28(6), pp.475~484 (2003), 대한치과보존학회
  37. Kim E, "Prospective clinical study evaluating endodontic microsurgery outcomes for cases with lesions of endodontic origin compared with cases with lesions of combined periodontal-endodontic origin", Journal Of Endodontics, 34, pp.546~551 (2008)
  38. Song M, "Prognostic factors for clinical outcomes in endodontic microsurgery:a retrospective study", J Endod, 37, pp.927~933 (2011)
  39. Chowdhry S, "Do not use epinephrine in digital blocks:myth or truth? Part II. A retrospective review of 1111cases", Plast Reconstr Surg, 126, pp.2031~2034 (2010)
  40. Häfner HM, "Epinephrinesupplemented local anesthetics for ear and nose surgery: clinical use without complications in more than 10,000 surgical procedures", J Dtsch Dermatol Ges, 3, pp.195~199 (2005)
  41. Lalonde D, "A multicenter prospective study of 3,110consecutive cases of elective epinephrine use in the fingers and hand: the Dalhousie Project clinical phase", J Hand Surg Am, 30, pp.1061~1067 (2005)
  42. Sylaidis P, "Digital blocks with adrenaline. An old dogma refuted", J Hand Surg Br, 23, pp.17~19 (1998)
  43. Denkler K., "A comprehensive review of epinephrine in the finger: to do or not to do", Plast Reconstr Surg, 108, pp.114~124 (2001)
  44. 김의성, "Cardiovascular effect of epinephrine in endodontic microsurgery: a review", Restorative Dentistry and Endodontics, 38(4), pp.187~193 (2013), 대한치과보존학회
  45. Troullos ES, "Plasma epinephrine levels and cardiovascular response to high administered doses of epinephrine contained in local anesthesia", Anesth Prog, 34, pp.10~13 (1987)
  46. Gogerty JH, "Vasopressor effects of topical epinephrine in certain dental procedures", Oral Surg Oral Med Oral Pathol, 10, pp.614~622 (1957)
  47. Wood M, "Comparison of intraosseous and infiltration injections for venous lidocaine blood concentrations and heart rate changes after injection of 2% lidocaine with 1:100,000 epinephrine", J Endod, 31, pp.435~438 (2005)
  48. Besner E., "Systemic effects of racemic epinephrine when applied to the bone cavity during periapical surgery", Va Dent J, 49, pp.9~12 (1972)
  49. Ferry DR, "Epinephrine-induced myocardial infarction in a patient with angiographically normal coronary arteries", Am Heart J, 111, pp.1193~1195 (1986)
  50. Foster CA, "Aston SJ. Propranolol-epinephrine interaction: a potential disaster", Plast Reconstr Surg, 72, pp.74~78 (1983)
  51. Lee JY, "Cardiac arrest induced by submucosal injection of epinephrine in a patient with variant angina", Rhinology, 48, pp.251~253 (2010)
  52. Umino M, "Unexpected atrial fibrillation during tooth extraction in a sedated elderly patient", Anesth Prog, 41, pp.77~80 (1994)
  53. Monsel L., "Proprieté hémostatique du sulfate de peroxyde de Fer", Rec Mem Med Milit, 17, pp.424~ (1856)
  54. Fischer DE., , Gen Dent, 35, pp.178~182 (1987)
  55. Smith NL, "Ferric sulfate pulpotomy in primary molars: a retrospective study", Pediatr Dent, 22, pp.192~199 (2000)
  56. von Arx T, "Clinical and radiographic assessment of various predictors for healing outcome 1year after periapical surgery", J Endod, 33, pp.123~128 (2007)
  57. von Arx T, "Five-year longitudinal assessment of the prognosis of apical microsurgery", J Endod, 38, pp.570~579 (2012)
  58. Evans BE., "Local hemostatic agents", N Y J Dent, 47, pp.109~114 (1977)
  59. Davis JR, "Effects of Monsel’s solution in uterine cervix", Am J Clin Pathol, 82, pp.332~335 (1984)
  60. Sawchuk WS, "Delayed healing in full-thickness wounds treated with aluminum chloride solution. A histologic study with evaporimetry correlation", J Am Acad Dermatol, 15, pp.982~989 (1986)
  61. Armstrong RB, "Punch biopsy wounds treated with Monsel’s solution or a collagen matrix", A comparison of healing. Arch Dermatol, 122, pp.546~549 (1986)
  62. Amazon K, "Ferrugination caused by Monsel’s solution. Clinical observations and experimentations", Am J Dermatopathol, 2, pp.197~205 (1980)
  63. Duray PH, "Recurrent dysplastic nevus following shave excision", J Dermatol Surg Oncol, 10, pp.811~815 (1984)
  64. Horbett TA., "Principles underlying the role of adsorbed plasma proteins in blood interactions with foreign materials", Cardiovasc Pathol, (Supplement 2), pp.137~148 (1993)
  65. Ziats NP, "Adsorption of Hageman factor (factor XII) and other human plasma proteins to biomedical polymers", J Lab Clin Med, 116, pp.687~696 (1990)
  66. Thomas MV, "Calcium sulfate: properties and clinical applications", J Biomed Mater Res B Appl Biomater, 88, pp.597~610 (2009)
  67. Payne JM, "Migration of human gingival fibroblasts over guided tissue regeneration barrier materials", J Periodontol, 67, pp.236~244 (1996)
  68. Guarnieri R, "Medical grade calcium sulfate hemihydrate in healing of human extraction sockets:clinical and histological observations at 3 months", J Periodontol, 75, pp.902~908 (2004)
  69. Larson PO., "Topical hemostatic agents for dermatologic surgery", J Dermatol Surg Oncol, 14, pp.623~632 (1988)
  70. Palm MD, "Topical hemostatic agents: a review", Dermatol Surg, 34, pp.431~445 (2008)
  71. Scarano A, "Maxillary sinus augmentation with different biomaterials: a comparative histologic and histomorphometric study in man", Implant Dent, 15, pp.197~207 (2006)
  72. Orsini M, "Comparison of calcium sulfate and autogenous bone graft to bioabsorbable membranes plus autogenous bone graft in the treatment of intrabony periodontal defects: a split-mouth study", J Periodontol, 72, pp.296~302 (2001)
  73. Aichelmann-Reidy ME, "Clinical evaluation of calcium sulfate in combination with demineralized freeze-dried bone allograft for the treatment of human intraosseous defects", J Periodontol, 75, pp.340~347 (2004)
  74. Kim CK, "Periodontal repair in intrabony defects treated with a calcium sulfate implant and calcium sulfate barrier", J Periodontol, 69, pp.1317~1324 (1998)
  75. Shaffer CD, "The use of plaster of paris in treating infrabony periodontal defects in humans", J Periodontol, 42, pp.685~690 (1971)
  76. Kalbermatten DF, "Cottoninduced pseudotumor of the femur", Skeletal Radiol, 30, pp.415~417 (2001)
  77. Sexton CC, "Case report 174:‘Cottonballoma’ of femur (due to retained surgical sponge with foreign body giant cell reaction)", Skeletal Radiol, 7, pp.211~213 (1981)
  78. Petrino JA, "Challenges in regenerative endodontics:a case series", J Endod, 36, pp.536~541 (2010)
  79. Ferris DM, "Perforation repair comparing two types of mineral trioxide aggregate", J Endod, 30, pp.422~424 (2004)
  80. Stein MD, "Collagen sponge as a topical hemostatic agent in mucogingival surgery", J Periodontol, 56, pp.35~38 (1985)
  81. Chvapil M., "Collagen sponge: theory and practice of medical applications", J Biomed Mater Res, 11, pp.721~741 (1977)
  82. Mannai C, "Histological evaluation of purified bovine tendon collagen sponge in tooth extraction sites in dogs", Oral Surg Oral Med Oral Pathol, 61, pp.315~323 (1986)

관련 논문AI추천

이 간행물의 다른 논문 (11건)