본문 바로가기
KERD
논문KCI 등재

Post-COVID-19 pain syndrome: a descriptive study in Turkish population

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

Background: The new type of corona virus has a wide range of symptoms. Some people who have COVID-19 can experience long-term effects from their infection, known as post-COVID conditions. The authors aimed to investigate prolonged musculoskeletal pain as a symptom of the post-COVID-19 condition. Methods: This is a descriptive study on the patients who were diagnosed with COVID-19 in a university hospital, between March 2020 and March 2021. Patient records and an extensive questionnaire were used to obtain relevant demographic and clinical characteristics, including hospitalization history, comorbidities, smoking history, duration of the pain, the area of pain, and the presence of accompanying neuropathic symptoms. Results: Of the diagnosed patients, 501 agreed to participate in the study. Among the participants, 318 had musculoskeletal pain during COVID-19 infection, and 69 of them reported prolonged pain symptoms as part of their a post-COVID condition which could not be attributed to any other cause. The mean duration of pain was 4.38 ± 1.73 months, and the mean pain level was 7.2 ± 4.3. Neuropathic pain symptoms such as burning sensation (n = 16, 23.2%), numbness (n = 15, 21.7%), tingling (n = 10, 14.5%), stinging (n = 4, 5.8%), freezing (n = 1, 1.4%) were accompanied in patients with prolonged musculoskeletal pain. Conclusions: Patients with COVID-19 may develop prolonged musculoskeletal pain. In some patients, neuropathic pain accompanies it. Awareness of prolonged post- COVID-19 pain is crucial for its early detection and management.

Abstract

Background: The new type of corona virus has a wide range of symptoms. Some people who have COVID-19 can experience long-term effects from their infection, known as post-COVID conditions. The authors aimed to investigate prolonged musculoskeletal pain as a symptom of the post-COVID-19 condition. Methods: This is a descriptive study on the patients who were diagnosed with COVID-19 in a university hospital, between March 2020 and March 2021. Patient records and an extensive questionnaire were used to obtain relevant demographic and clinical characteristics, including hospitalization history, comorbidities, smoking history, duration of the pain, the area of pain, and the presence of accompanying neuropathic symptoms. Results: Of the diagnosed patients, 501 agreed to participate in the study. Among the participants, 318 had musculoskeletal pain during COVID-19 infection, and 69 of them reported prolonged pain symptoms as part of their a post-COVID condition which could not be attributed to any other cause. The mean duration of pain was 4.38 ± 1.73 months, and the mean pain level was 7.2 ± 4.3. Neuropathic pain symptoms such as burning sensation (n = 16, 23.2%), numbness (n = 15, 21.7%), tingling (n = 10, 14.5%), stinging (n = 4, 5.8%), freezing (n = 1, 1.4%) were accompanied in patients with prolonged musculoskeletal pain. Conclusions: Patients with COVID-19 may develop prolonged musculoskeletal pain. In some patients, neuropathic pain accompanies it. Awareness of prolonged post- COVID-19 pain is crucial for its early detection and management.

참고문헌 (28)

  1. Wu Z, "Characteristics of and important lessons from the coronavirus disease 2019(COVID-19)outbreak in China : summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention", JAMA, 323, pp.1239~1242 (2020)
  2. Cucinotta D, "WHO declares COVID-19 a pandemic", Acta Biomed, 91, pp.157~160 (2020)
  3. Broderick G, "A formal analysis of cytokine networks in chronic fatigue syndrome", Brain Behav Immun, 24, pp.1209~1217 (2010)
  4. Ackermann M, "Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19", N Engl J Med, 383, pp.120~128 (2020)
  5. Garg P, "The “post-COVID” syndrome:how deep is the damage?", J Med Virol, 93, pp.673~674 (2021)
  6. Yalcin HC, "Do changes in ACE-2 expression affect SARS-CoV-2 virulence and related complications : a closer look into membranebound and soluble forms", Int J Mol Sci, 22, pp.6703~ (2021)
  7. Pons S, "The vascular endothelium : the cornerstone of organ dysfunction in severe SARSCoV-2 infection", Crit Care, 24, pp.353~ (2020)
  8. Paliwal VK, "Neuromuscular presentations in patients with COVID-19", Neurol Sci, 41, pp.3039~3056 (2020)
  9. To KF, "Exploring the pathogenesis of severe acute respiratory syndrome(SARS) : the tissue distribution of the coronavirus(SARS-CoV)and its putative receptor, angiotensin-converting enzyme 2(ACE2)", J Pathol, 203, pp.740~743 (2004)
  10. Grichnik KP, "The difference between acute and chronic pain", Mt Sinai J Med, 58, pp.217~220 (1991)
  11. Treede RD, "A classification of chronic pain for ICD-11", Pain, 156, pp.1003~1007 (2015)
  12. Trouvin AP, "New concepts of pain", Best Pract Res Clin Rheumatol, 33, pp.101415~ (2019)
  13. Campbell WI, "Visual analogue measurement of pain", Ulster Med J, 59, pp.149~154 (1990)
  14. Li LQ, "COVID-19 patients’ clinical characteristics, discharge rate, and fatality rate of meta-analysis", J Med Virol, 92, pp.577~583 (2020)
  15. Zhu J, "Clinicopathological characteristics of 8697 patients with COVID-19 in China : a meta-analysis", Fam Med Community Health, 8, pp.e000406~ (2020)
  16. Lechien JR, "Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease(COVID-19) : a multicenter European study", Eur Arch Otorhinolaryngol, 277, pp.2251~2261 (2020)
  17. Lechien JR, "Clinical and epidemiological characteristics of 1420 European patients with mild-to-moderate coronavirus disease 2019", J Intern Med, 288, pp.335~344 (2020)
  18. Corsini Campioli C, "Clinical predictors and timing of cessation of viral RNA shedding in patients with COVID-19", J Clin Virol, 130, pp.104577~ (2020)
  19. Attal N, "Potential for increased prevalence of neuropathic pain after the COVID-19 pandemic", Pain Rep, 6, pp.e884~ (2021)
  20. Gan EY, "Management of herpes zoster and post-herpetic neuralgia", Am J Clin Dermatol, 14, pp.77~85 (2013)
  21. Aksan F, "A COVID-19 patient with intense burning pain", J Neurovirol, 26, pp.800~801 (2020)
  22. Agyeman AA, "Smell and taste dysfunction in patients with COVID-19 : a systematic review and meta-analysis", Mayo Clin Proc, 95, pp.1621~1631 (2020)
  23. Chung TW, "Olfactory dysfunction in coronavirus disease 2019patients: observational cohort study and systematic review", Open Forum Infect Dis, 7, pp.ofaa199~ (2019)
  24. Bolay H, "COVID-19 is a real headache!Headache", 60, pp.1415~1421 (2020)
  25. Varga Z, "Endothelial cell infection and endotheliitis in COVID-19", Lancet, 395, pp.1417~1418 (2020)
  26. Pinzon RT, "Neurologic characteristics in coronavirus disease 2019(COVID-19) : a systematic review and meta-analysis", Front Neurol, 11, pp.565~ (2020)
  27. Uygun Ö, "Headache characteristics in COVID-19 pandemic-a survey study", J Headache Pain, 21, pp.121~ (2020)

관련 논문AI추천

이 간행물의 다른 논문 (13건)