Comparison of the effects of transcutaneous electrical nerve stimulation and interferential current therapies in central sensitization in patients with knee osteoarthritis
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background: This study is primarily aimed to determine whether transcutaneous electrical nerve stimulation (TENS) and interferential current (IFC) treatments have any effect on central sensitization (CS) in patients with knee osteoarthritis (OA) and to investigate which treatment is more effective. Methods: In this randomized controlled trial, 80 patients were randomized into four treatment groups: TENS, Plasebo-TENS, IFC, and Plasebo-IFC. All interventions were applied 5 times a week for 2 weeks. Primary outcome was pressure pain threshold (PPT), which is accepted as the objective indicator of CS, at the painful knee and at the shoulder as a painless distant point. Other outcome measures were the visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index, Timed Up and Go Test, pain catastrophizing scale, Beck Depression Inventory, and Tampa Scale of Kinesiophobia. Results: All assessment parameters were improved, without a significant difference among the groups except PPT. PPT scores were significantly improved in TENS and IFC groups when compared with the sham groups at 2 weeks and 3 months. In addition, this improvement was even more pronounced in the TENS group. Multivariable logistic regression analysis showed that the patient’s inclusion in the TENS group, an initial high PPT, and an initial low VAS score were independent risk factors for improvement in the PPT. Conclusions: This study shows that TENS and IFC reduced pain sensitivity as compared to placebo groups in patients with knee OA. This effect was more pronounced in the TENS group.
Abstract
Background: This study is primarily aimed to determine whether transcutaneous electrical nerve stimulation (TENS) and interferential current (IFC) treatments have any effect on central sensitization (CS) in patients with knee osteoarthritis (OA) and to investigate which treatment is more effective. Methods: In this randomized controlled trial, 80 patients were randomized into four treatment groups: TENS, Plasebo-TENS, IFC, and Plasebo-IFC. All interventions were applied 5 times a week for 2 weeks. Primary outcome was pressure pain threshold (PPT), which is accepted as the objective indicator of CS, at the painful knee and at the shoulder as a painless distant point. Other outcome measures were the visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index, Timed Up and Go Test, pain catastrophizing scale, Beck Depression Inventory, and Tampa Scale of Kinesiophobia. Results: All assessment parameters were improved, without a significant difference among the groups except PPT. PPT scores were significantly improved in TENS and IFC groups when compared with the sham groups at 2 weeks and 3 months. In addition, this improvement was even more pronounced in the TENS group. Multivariable logistic regression analysis showed that the patient’s inclusion in the TENS group, an initial high PPT, and an initial low VAS score were independent risk factors for improvement in the PPT. Conclusions: This study shows that TENS and IFC reduced pain sensitivity as compared to placebo groups in patients with knee OA. This effect was more pronounced in the TENS group.
참고문헌 (45)
- Lohmander LS, "Clinical update : treating osteoarthritis", Lancet, 370, pp.2082~2084 (2007)
- Perrot S, "Osteoarthritis pain", Best Pract Res Clin Rheumatol, 29, pp.90~97 (2015)
- Fingleton C, "Pain sensitization in people with knee osteoarthritis : a systematic review and meta-analysis", Osteoarthritis Cartilage, 23, pp.1043~1056 (2015)
- Bannuru RR, "OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis", Osteoarthritis Cartilage, 27, pp.1578~1589 (2019)
- Lluch E, "Clinical descriptors for the recognition of central sensitization pain in patients with knee osteoarthritis", Disabil Rehabil, 40, pp.2836~2845 (2018)
- Moore RL, "The relationship between clinical and quantitative measures of pain sensitization in knee osteoarthritis", Clin J Pain, 36, pp.336~343 (2020)
- Arendt-Nielsen L, "Altered central sensitization and pain modulation in the CNS in chronic joint pain", Curr Osteoporos Rep, 13, pp.225~234 (2015)
- Akin-Akinyosoye K, "Traits associated with central pain augmentation in the Knee Pain In the Community(KPIC)cohort", Pain, 159, pp.1035~1044 (2018)
- Neblett R, "The Central Sensitization Inventory(CSI) : establishing clinically significant values for identifying central sensitivity syndromes in an outpatient chronic pain sample", J Pain, 14, pp.438~445 (2013)
- Jeong Y, "Mechanism of hyperalgesia following cutaneous inflammation by complete Freund adjuvant", Korean J Pain, 13, pp.164~174 (2000)
- Cherian JJ, "The effects of various physical non-operative modalities on the pain in osteoarthritis of the knee", Bone Joint J, 98-B(1 Suppl A), pp.89~94 (2016)
- Tuncer T, "2017 update of the Turkish League Against Rheumatism(TLAR)evidence-based recommendations for the management of knee osteoarthritis", Rheumatol Int, 38, pp.1315~1331 (2018)
- Hochberg MC, "American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee", Arthritis Care Res (Hoboken), 64, pp.465~474 (2012)
- Vance CGT, "Using TENS for pain control:update on the state of the evidence", Medicina (Kaunas), 58, pp.1332~ (2022)
- Rampazo ÉP, "Analgesic effects of interferential current therapy : a narrative review", Medicina (Kaunas), 58, pp.141~ (2022)
- Beckwée D, "Effect of tens on pain in relation to central sensitization in patients with osteoarthritis of the knee : study protocol of a randomized controlled trial", Trials, 13, pp.21~ (2012)
- Chen HL, "Effectiveness of interferential current therapy in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials", Sci Rep, 12, pp.9694~ (2022)
- Atamaz FC, "Comparison of the efficacy of transcutaneous electrical nerve stimulation, interferential currents, and shortwave diathermy in knee osteoarthritis : a double-blind, randomized, controlled, multicenter study", Arch Phys Med Rehabil, 93, pp.748~756 (2012)
- Kawasaki T, "Assessment of the American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the knee", Ryumachi, 38, pp.2~5 (1998)
- Kellgren JH, "Radiological assessment of osteo-arthrosis", Ann Rheum Dis, 16, pp.494~502 (1957)
- "A review on transcutaneous electrical nerve stimulation and its applications" (2020)[URL]
- Heller GZ, "How to analyze the visual analogue scale : myths, truths and clinical relevance", Scand J Pain, 13, pp.67~75 (2016)
- Podsiadlo D, "The timed"Up & Go" : a test of basic functional mobility for frail elderly persons", J Am Geriatr Soc, 39, pp.142~148 (1991)
- Tüzün EH, "Acceptability, reliability, validity and responsiveness of the Turkish version of WOMAC osteoarthritis index", Osteoarthritis Cartilage, 13, pp.28~33 (2005)
- İlçin N, "Cross-cultural adaptation and validation of the Turkish version of the pain catastrophizing scale among patients with ankylosing spondylitis", J Phys Ther Sci, 28, pp.298~303 (2016)
- Sullivan MJ, "The pain catastrophizing scale : development and validation", Psychol Assess, 7, pp.524~532 (1995)
- Hisli N, "Use of the Beck Depression Inventory with Turkish university students : reliability, validity and factor analysis", Turk J Psychol, 7, pp.3~13 (1989)
- Tunca Yılmaz Ö, "Turkish version of the Tampa Scale for Kinesiophobia and its test-retest reliability", Fizyoter Rehabil, 22, pp.44~49 (2011)
- Vlaeyen JW, "The role of fear of movement", (re)injury in pain disability, 1995, pp.5, 235~252
- Suokas AK, "Quantitative sensory testing in painful osteoarthritis : a systematic review and meta-analysis", Osteoarthritis Cartilage, 20, pp.1075~1085 (2012)
- Walton DM, "Clinical pressure pain threshold testing in neck pain : comparing protocols, responsiveness, and association with psychological variables", Phys Ther, 94, pp.827~837 (2014)
- Wu Y, "Effects of transcutaneous electrical nerve stimulation(TENS)in people with knee osteoarthritis : A systematic review and meta-analysis", Clin Rehabil, 36, pp.472~485 (2022)
- Palmer S, "Transcutaneous electrical nerve stimulation as an adjunct to education and exercise for knee osteoarthritis : a randomized controlled trial", Arthritis Care Res (Hoboken), 66, pp.387~394 (2014)
- Rakel BA, "Transcutaneous electrical nerve stimulation for the control of pain during rehabilitation after total knee arthroplasty : a randomized, blinded, placebo-controlled trial", Pain, 155, pp.2599~2611 (2014)
- Kim JH, "Effects of localized heating on pain, skin perfusion, and wound healing after lumbar decompression", J Neurosci Nurs, 52, pp.251~256 (2020)
- Doménech J, "Changes in catastrophizing and kinesiophobia are predictive of changes in disability and pain after treatment in patients with anterior knee pain", Knee Surg Sports Traumatol Arthrosc, 22, pp.2295~2300 (2014)
- Wade JB, "Is pain catastrophizing a stable trait or dynamic state in patients scheduled for knee arthroplasty?", Clin J Pain, 28, pp.122~128 (2012)
- Carlesso LC, "Pain susceptibility phenotypes in those free of knee pain with or at risk of knee osteoarthritis : the multicenter osteoarthritis study", Arthritis Rheumatol, 71, pp.542~549 (2019)
- Alfieri FM, "Cutaneous temperature and pressure pain threshold in individuals with knee osteoarthritis", Reumatologia, 58, pp.272~276 (2020)
- Hahm SC, "Transcutaneous electrical nerve stimulation reduces knee osteoarthritic pain by inhibiting spinal glial cells in rats", Phys Ther, 99, pp.1211~1223 (2019)
- Vance CG, "Effects of transcutaneous electrical nerve stimulation on pain, pain sensitivity, and function in people with knee osteoarthritis : a randomized controlled trial", Phys Ther, 92, pp.898~910 (2012)
- Hou CR, "Immediate effects of various physical therapeutic modalities on cervical myofascial pain and triggerpoint sensitivity", Arch Phys Med Rehabil, 83, pp.1406~1414 (2002)
- Moss P, "Subjects with knee osteoarthritis exhibit widespread hyperalgesia to pressure and cold", PLoS One, 11, pp.e0147526~ (2016)
- Arendt-Nielsen L, "Pain and sensitization after total knee replacement or nonsurgical treatment in patients with knee osteoarthritis : Identifying potential predictors of outcome at 12 months", Eur J Pain, 22, pp.1088~1102 (2018)
- O’Leary H, "Pain sensitization associated with nonresponse after physiotherapy in people with knee osteoarthritis", Pain, 159, pp.1877~1886 (2018)