The current status of fibromyalgia in Korea: an electronic population health data study in Korea
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Background: Fibromyalgia (FM) is a complex disorder characterized by widespread chronic pain and tenderness in the muscles, ligaments, and soft tissues. It is a chronic pain condition often accompanied by other symptoms and comorbidities. To effectively manage FM, it is crucial to obtain fundamental epidemiological data pertaining to the target population. Therefore, this study was conducted to elucidate the epidemiological characteristics of FM in the Korean population. Methods: Population-based medical data of 51,276,314 subscribers to the National Health Insurance Service of Korea from 2014 to 2018 were used in this study. Results: The overall incidence of FM ranged from 441 (2014) to 541 (2018) cases per 100,000 person-years, with a higher prevalence observed among female patients compared to male patients. The incidence gradually increased until middle age, followed by a decrease. The highest incidence rates were observed in the fifth decade of life for females and the sixth decade of life for males. When categorizing the affected parts of the body, the shoulder region was observed to be the most frequently affected. A comparison of the drug prescriptions based on medical specialty showed that antidepressants were the most commonly prescribed medications. The management of FM leads to consistent increases in medical expenses, regional disparities, and variations in prescription patterns across different medical specialties. Conclusions: The findings of this study will not only contribute to the understanding of FM characteristics but also provide a vital foundation for efficient management of FM in Korea.
Abstract
Background: Fibromyalgia (FM) is a complex disorder characterized by widespread chronic pain and tenderness in the muscles, ligaments, and soft tissues. It is a chronic pain condition often accompanied by other symptoms and comorbidities. To effectively manage FM, it is crucial to obtain fundamental epidemiological data pertaining to the target population. Therefore, this study was conducted to elucidate the epidemiological characteristics of FM in the Korean population. Methods: Population-based medical data of 51,276,314 subscribers to the National Health Insurance Service of Korea from 2014 to 2018 were used in this study. Results: The overall incidence of FM ranged from 441 (2014) to 541 (2018) cases per 100,000 person-years, with a higher prevalence observed among female patients compared to male patients. The incidence gradually increased until middle age, followed by a decrease. The highest incidence rates were observed in the fifth decade of life for females and the sixth decade of life for males. When categorizing the affected parts of the body, the shoulder region was observed to be the most frequently affected. A comparison of the drug prescriptions based on medical specialty showed that antidepressants were the most commonly prescribed medications. The management of FM leads to consistent increases in medical expenses, regional disparities, and variations in prescription patterns across different medical specialties. Conclusions: The findings of this study will not only contribute to the understanding of FM characteristics but also provide a vital foundation for efficient management of FM in Korea.
참고문헌 (24)
- Chinn S, "Fibromyalgia pathogenesis and treatment options update", Curr Pain Headache Rep, 20, pp.25~ (2016)
- Arzu Yagiz On, "Relationships of autonomic dysfunction with disease severity and neuropathic pain features in fibromyalgia: is it really a sympathetically maintained neuropathic pain?", The Korean Journal of Pain, 35(3), pp.327~335 (2022), 대한통증학회[DOI]
- Wolfe F, "The American College of Rheumatology 1990 criteria for the classification of fibromyalgia Report of the multicenter criteria committee", Arthritis Rheum, 33, pp.160~172 (1990)
- Banafsheh Ghavidel-Parsa, "Fibromyalgia diagnostic model derived from combination of American College of Rheumatology 1990 and 2011 criteria", The Korean Journal of Pain, 32(2), pp.120~128 (2019), 대한통증학회[DOI]
- Clauw DJ, "Chronic widespread pain and fibromyalgia : what we know, and what we need to know", Best Pract Res Clin Rheumatol, 17, pp.685~701 (2003)
- Carville SF, "EULAR evidence-based recommendations for the management of fibromyalgia syndrome", Ann Rheum Dis, 67, pp.536~541 (2008)
- Arnold LM, "Improving the recognition and diagnosis of fibromyalgia", Mayo Clin Proc, 86, pp.457~464 (2011)
- Ali Bidari, "Challenges in fibromyalgia diagnosis: from meaning of symptoms to fibromyalgia labeling", The Korean Journal of Pain, 31(3), pp.147~154 (2018), 대한통증학회
- 이영숙, "국내 허가된 해열·진통·소염제의 치료중복 주의 가이드라인 개발", 한국임상약학회지, 20(3), pp.213~220 (2010), 한국임상약학회
- 김성호, "한국의 두 지역사회에서 섬유근통 증후군과만성 광범위 통증의 유병률과 위험요인", 대한류마티스학회지, 13(1), pp.18~25 (2006), 대한류마티스학회
- Lee HJ, "Prevalence of fibromyalgia in fourteen Korean tertiary care university hospital pain clinics", J Pain Res, 11, pp.2417~2423 (2018)
- Forseth KO, "A population study of the incidence of fibromyalgia among women aged 26-55 yr", Br J Rheumatol, 36, pp.1318~1323 (1997)
- Weir PT, "The incidence of fibromyalgia and its associated comorbidities : a populationbased retrospective cohort study based on International Classification of Diseases, 9th Revision codes", J Clin Rheumatol, 12, pp.124~128 (2006)
- Wolfe F, "Fibromyalgia diagnosis and biased assessment : sex, prevalence and bias", PLoS One, 13, pp.e0203755~ (2018)
- Hadker N, "Primary care physicians’ perceptions of the challenges and barriers in the timely diagnosis, treatment and management of fibromyalgia", Pain Res Manag, 16, pp.440~444 (2011)
- Sommer C, "Drug therapy of fibromyalgia syndrome Systematic review, meta-analysis and guideline", Schmerz, 26, pp.297~310 (2012)
- Fitzcharles MA, "2012 Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: executive summary", Pain Res Manag, 18, pp.119~126 (2013)
- Macfarlane GJ, "EULAR revised recommendations for the management of fibromyalgia", Ann Rheum Dis, 76, pp.318~328 (2017)
- Sarzi-Puttini P, "Fibromyalgia syndrome: the pharmacological treatment options", Reumatismo, 60(Suppl 1), pp.50~58 (2008)
- Harris RE, "Decreased central mu-opioid receptor availability in fibromyalgia", J Neurosci, 27, pp.10000~10006 (2007)
- Brummett CM, "Survey criteria for fibromyalgia independently predict increased postoperative opioid consumption after lower-extremity joint arthroplasty : a prospective, observational cohort study", Anesthesiology, 119, pp.1434~1443 (2013)
- Joon-Ho Lee, "Still a threatening opioid wave: it is time for the protagonist to step up!", The Korean Journal of Pain, 36(1), pp.1~3 (2023), 대한통증학회[DOI]
- Goldenberg DL, "Management of fibromyalgia syndrome", JAMA, 292, pp.2388~2395 (2004)
- McNett M, "Treatment patterns among physician specialties in the management of fibromyalgia : results of a cross-sectional study in the United States", Curr Med Res Opin, 27, pp.673~683 (2011)